Giers, G; Wenzel, F; Fischer, J; Stockschläder, M; Riethmacher, R; Lorenz, H; Tutschek, B (2010). Retrospective comparison of maternal vs. HPA-matched donor platelets for treatment of fetal alloimmune thrombocytopenia. Vox sanguinis, 98(3 Pt 2), pp. 423-30. Oxford: Wiley-Blackwell 10.1111/j.1423-0410.2009.01268.x
Full text not available from this repository. (Request a copy)In fetal alloimmune thrombocytopenia (FAIT), transplacental maternal antibodies cause destruction of fetal platelets. FAIT is similar to fetal Rhesus haemolytic disease, but half of the affected fetuses are born to primiparous women. In 10-20% of cases, prenatal and perinatal intracranial haemorrhages are reported. Different therapeutic approaches have been described, including maternally administered high-dose intravenous immunoglobulin (high dose IVIG) without or with steroids or intrauterine transfusion (IUT) of compatible platelets. For the latter, the use of plasma-free maternal and donor platelets has been described, but a comparison of these two sources of platelets has not been reported.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Tutschek, Boris |
ISSN: |
0042-9007 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:07 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.1111/j.1423-0410.2009.01268.x |
PubMed ID: |
19874573 |
Web of Science ID: |
000275530800005 |
URI: |
https://boris.unibe.ch/id/eprint/123 (FactScience: 196228) |
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