Treatment of fibrostenotic and fistulizing Crohn's disease

Schoepfer, Alain M; Safroneeva, Ekaterina; Vavricka, Stephan R; Peyrin-Biroulet, Laurent; Mottet, Christian (2012). Treatment of fibrostenotic and fistulizing Crohn's disease. Digestion, 86(Sup 1), pp. 23-27. Basel: Karger 10.1159/000341961

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The majority of Crohn's disease patients will develop a complicated disease course over time which is characterized by the occurrence of stricturing and penetrating disease. Penetrating disease comprises internal fistulas (e.g. enteroenteric) and perianal disease. A complicated disease course may be associated with considerable morbidity and professional and personal disabilities. Treatment options for fibrostenotic Crohn's disease comprise endoscopic balloon dilation, stricturoplasties and surgical resection. Treatment of symptomatic perianal fistulizing disease is based on antibiotics, immunomodulators and anti-TNF drugs. Surgical measures include fistula drainage by means of setons, temporary ileostomy or a proctectomy. The presence of internal fistulas often necessitates surgical measures. A close collaboration between the gastroenterologist and the surgeon is mandatory to solve these interdisciplinary challenges.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Safroneeva, Ekaterina

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0012-2823

Publisher:

Karger

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:35

Last Modified:

21 Jun 2023 12:29

Publisher DOI:

10.1159/000341961

PubMed ID:

23051723

Web of Science ID:

000309695600006

BORIS DOI:

10.7892/boris.14033

URI:

https://boris.unibe.ch/id/eprint/14033 (FactScience: 220832)

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