Zuidema, Xander; Dünser, Martin W; Wenzel, Volker; Rozendaal, Frans W; de Jager, Cornelis P C (2006). Terlipressin as an adjunct vasopressor in refractory hypotension after tricyclic antidepressant intoxication. Resuscitation, 72(2), pp. 319-23. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2006.07.005
Full text not available from this repository. (Request a copy)AIM OF STUDY: To report the management of cardiovascular failure refractory to standard catecholamine therapy with terlipressin in a patient with tricyclic antidepressant (TCA) intoxication. CASE REPORT: A 41-year-old woman, with suicidal ingestion of 11.25 g amitriptyline and 1500 mg diclofenac, was admitted to the emergency department. After 30 min in ventricular fibrillation, with ongoing CPR, she regained a potentially perfusing rhythm, but with hypotension refractory to standard catecholamine therapy with adrenaline, 2 microg/kg/min (norepinephrine); adrenaline, 1 microg/kg/min (epinephrine) until 55 min after admission. An injection of 1 mg terlipressin restored mean arterial blood pressure >65 mmHg within 10 min. Ten hours after admission to the intensive care unit, catecholamine support could be withdrawn because of a stable haemodynamic state. Within 7 days, all organ function recovered, and the patient regained full neurological function. CONCLUSIONS: Successful management of cardiovascular failure with terlipressin after TCA intoxication refractory to catecholamines suggests a potential role for terlipressin as an adjunct vasopressor in severely hypotensive patients.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care |
UniBE Contributor: |
Dünser, Martin Wolfgang |
ISSN: |
0300-9572 |
ISBN: |
17123689 |
Publisher: |
Elsevier Science Ireland |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:49 |
Last Modified: |
05 Dec 2022 14:15 |
Publisher DOI: |
10.1016/j.resuscitation.2006.07.005 |
PubMed ID: |
17123689 |
Web of Science ID: |
000244022400022 |
URI: |
https://boris.unibe.ch/id/eprint/20419 (FactScience: 3710) |
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