[White sponge naevus. Report of a family with respect to histopathologic, cytopathologic and DNA-cytometric aspects]

Harnisch, Hendrik; Paredes, Bruno E; Spieler, Peter; Bornstein, Michael M (2006). [White sponge naevus. Report of a family with respect to histopathologic, cytopathologic and DNA-cytometric aspects]. Schweizerische Monatsschrift für Zahnmedizin, 116(11), pp. 1130-44. Bern: Schweizerische Zahnärzte-Gesellschaft

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The white sponge naevus is a rare benign, hereditary autosomal dominant disorder of the mucosa. The oral mucosa is most often affected, but vaginal and anal mucosal surfaces may also be involved. Clinically, a whitish-grey, ragged, and folded surface that has no clear demarcation and appears sponge-like is characteristic, often creating problems in differential diagnosis. A potential risk for malignant transformation of white sponge naevus lesions has not been reported. The therapy for this benign hereditary disorder is unknown, however does not appear to be necessary. In the present report of a family with known white sponge naevus in three different generations, clinical, histopathologic, cytopathologic, DNA-cytomertric, and genetic aspects are described and discussed.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology
UniBE Contributor:	Bornstein, Michael
ISSN:	0256-2855
Publisher:	Schweizerische Zahnärzte-Gesellschaft
Language:	English
Submitter:	Eveline Carmen Schuler
Date Deposited:	04 Oct 2013 14:51
Last Modified:	05 Dec 2022 14:15
PubMed ID:	17144625
URI:	https://boris.unibe.ch/id/eprint/21601 (FactScience: 8277)