Fux, Christoph A; Christen, Anna; Zgraggen, Susanne; Mohaupt, Markus G; Furrer, Hansjakob (2007). Effect of tenofovir on renal glomerular and tubular function. AIDS, 21(11), pp. 1483-5. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/QAD.0b013e328216f15b
Full text not available from this repository. (Request a copy)To evaluate tenofovir-related nephropathy, we quantified calculated glomerular filtration rates (GFR) and renal tubular function in 46 tenofovir-treated patients and 25 without tenofovir. We also analysed patients who stopped tenofovir for drug-related nephrotoxicity at our clinic. Tenofovir use combined with non-nucleoside reverse transcriptase inhibitors, but not with protease inhibitors, resulted in a significant increase in calculated GFR. Tenofovir use was associated with significantly lower phosphatemia and a marginally increased fractional excretion of uric acid, but no other signs of tubulopathy.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology 04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension |
UniBE Contributor: |
Fux, Christoph Andreas, Mohaupt, Markus, Furrer, Hansjakob |
ISSN: |
0269-9370 |
ISBN: |
17589197 |
Publisher: |
Lippincott Williams & Wilkins |
Language: |
English |
Submitter: |
Markus Georg Mohaupt |
Date Deposited: |
04 Oct 2013 14:54 |
Last Modified: |
05 Dec 2022 14:16 |
Publisher DOI: |
10.1097/QAD.0b013e328216f15b |
PubMed ID: |
17589197 |
Web of Science ID: |
000248093600014 |
URI: |
https://boris.unibe.ch/id/eprint/23026 (FactScience: 38650) |
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