Schaub, A; von Gunten, S; Vogel, M; Wymann, S; Rüegsegger, M; Stadler, B M; Spycher, M; Simon, H-U; Miescher, S (2011). Dimeric IVIG contains natural anti-Siglec-9 autoantibodies and their anti-idiotypes. Allergy, 66(8), pp. 1030-7. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02579.x
Full text not available from this repository. (Request a copy)Intravenous immunoglobulin (IVIG) preparations are increasingly used for the treatment of autoimmune and chronic inflammatory diseases. Naturally occurring autoantibodies against Siglec-9 and Fas are thought to contribute to the anti-inflammatory effects of IVIG via cell death regulation of leukocytes and tissue cells. Dimeric IVIG fractions are suspected to contain idiotypic (Id)-anti-idiotypic complexes of antibodies, which might also include anti-Siglec-9 and anti-Fas autoantibodies.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute for Immunology [discontinued] 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
von Gunten, Stephan, Vogel, Monique, Rüegsegger, Michael, Stadler, Beda Martin, Simon, Hans-Uwe |
ISSN: |
0105-4538 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:12 |
Last Modified: |
05 Dec 2022 14:02 |
Publisher DOI: |
10.1111/j.1398-9995.2011.02579.x |
PubMed ID: |
21385183 |
Web of Science ID: |
000292457700007 |
URI: |
https://boris.unibe.ch/id/eprint/2665 (FactScience: 205511) |
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