Mamisch, TC; Menzel, MI; Welsch, GH; Bittersohl, B; Salomonowitz, E; Szomolanyi, P; Kordelle, J; Marlovits, S; Trattnig, S (2008). Steady-state diffusion imaging for MR in-vivo evaluation of reparative cartilage after matrix-associated autologous chondrocyte transplantation at 3 tesla--preliminary results. European journal of radiology, 65(1), pp. 72-9. Stuttgart: Thieme 10.1016/j.ejrad.2007.09.015
Full text not available from this repository. (Request a copy)OBJECTIVES: To demonstrate the feasibility of time-reversed fast imaging with steady-state precession (FISP) called PSIF for diffusion-weighted imaging of cartilage and cartilage transplants in a clinical study. MATERIAL AND METHODS: In a cross-sectional study 15 patients underwent MRI using a 3D partially balanced steady-state gradient echo pulse sequence with and without diffusion weighting at two different time points after matrix-associated autologous cartilage transplantation (MACT). Mean diffusion quotients (signal intensity without diffusion-weighting divided by signal intensity with diffusion weighting) within the cartilage transplants were compared to diffusion quotients found in normal cartilage. RESULTS: The global diffusion quotient found in repair cartilage was significantly higher than diffusion values in normal cartilage (p<0.05). There was a decrease between the earlier and the later time point after surgery. CONCLUSIONS: In-vivo diffusion-weighted imaging based on the PSIF technique is possible. Our preliminary results show follow-up of cartilage transplant maturation in patients may provide additional information to morphological assessment.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Orthopaedic Surgery |
UniBE Contributor: |
Mamisch, Tallal Charles, Bittersohl, Bernd |
ISSN: |
0720-048X |
ISBN: |
17977685 |
Publisher: |
Thieme |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:03 |
Last Modified: |
05 Dec 2022 14:19 |
Publisher DOI: |
10.1016/j.ejrad.2007.09.015 |
PubMed ID: |
17977685 |
Web of Science ID: |
000253086400009 |
URI: |
https://boris.unibe.ch/id/eprint/27441 (FactScience: 107635) |
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