[Unusual pulmonary presentation of systemic Langerhans cell histiocytosis]

Lega, J-C; Cottin, V; Schuller, A; Lazor, R; Jullien, D; Cordier, J F (2008). [Unusual pulmonary presentation of systemic Langerhans cell histiocytosis]. Revue de médecine interne, 29(8), pp. 669-72. Issy-les-Moulineaux (F): Elsevier Masson 10.1016/j.revmed.2007.12.017

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An 80-year-old nonsmoking man was referred to our hospital with bilateral perihilar pulmonary opacities. He had a history of epilepsy, sclerosing cholangitis, cutaneous lesions previously diagnosed as localised Langerhans cell histiocytosis. Symptoms included dry cough and dyspnea. Chest CT showed bilateral perihilar alveolar consolidation with bronchiectasis. Histological examination of a lung biopsy showed typical features of Langerhans cell granulomatosis. Investigations revealed anterior and posterior hypopituitarism. An important improvement occurred with corticosteroid and vinblastine treatment.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology

UniBE Contributor:

Lazor, Romain

ISSN:

0248-8663

ISBN:

18281129

Publisher:

Elsevier Masson

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:04

Last Modified:

05 Dec 2022 14:19

Publisher DOI:

10.1016/j.revmed.2007.12.017

PubMed ID:

18281129

Web of Science ID:

000259055500012

URI:

https://boris.unibe.ch/id/eprint/28054 (FactScience: 116218)

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