Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review

Hutter, Damian; Kingdom, John; Jaeggi, Edgar (2010). Causes and mechanisms of intrauterine hypoxia and its impact on the fetal cardiovascular system: a review. International journal of pediatrics, 2010, pp. 1-9. New York, N.Y.: Hindawi 10.1155/2010/401323

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Until today the role of oxygen in the development of the fetus remains controversially discussed. It is still believed that lack of oxygen in utero might be responsible for some of the known congenital cardiovascular malformations. Over the last two decades detailed research has given us new insights and a better understanding of embryogenesis and fetal growth. But most importantly it has repeatedly demonstrated that oxygen only plays a minor role in the early intrauterine development. After organogenesis has taken place hypoxia becomes more important during the second and third trimester of pregnancy when fetal growth occurs. This review will briefly adress causes and mechanisms leading to intrauterine hypoxia and their impact on the fetal cardiovascular system.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Hutter, Damian Marco

ISSN:

1687-9740

Publisher:

Hindawi

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

04 Oct 2013 14:13

Last Modified:

02 Mar 2023 23:20

Publisher DOI:

10.1155/2010/401323

BORIS DOI:

10.7892/boris.2829

URI:

https://boris.unibe.ch/id/eprint/2829 (FactScience: 205749)

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