Demertzis, S; Ringe, B; Gulba, D; Rosenthal, H; Pichlmayr, R (1994). Treatment of portal vein thrombosis by thrombectomy and regional thrombolysis. Surgery, 3(115), pp. 389-93. New York, N.Y.: Elsevier
Full text not available from this repository. (Request a copy)BACKGROUND. Portal vein thrombosis is a rare disorder. The prognosis of both the acute and the chronic forms is determined by the resulting acute or chronic portal hypertension. The therapeutic approach of choice is controversial. METHODS. A case of etiologically unclear thrombosis of the portal vein system in a young man is reported, which was treated successfully by means of portal vein thrombectomy combined with intraoperative and postoperative thrombolysis with recombinant tissue plasminogen activator (rTPA). RESULTS. Initial thrombectomy established sufficient venous return. However, rethrombosis of the portal vein occurred 2 days later. In a second operation rethrombectomy was followed by intraoperative regional application of rTPA, which was continued after operation during a period of 48 hours through a catheter inserted in a mesenteric vein. Patency of the portal system was confirmed 1 week after the procedure. The 1-year follow-up reconfirmed this result (through indirect portography and Doppler sonography). The patient received the anticoagulant phenprocoumon. CONCLUSIONS. The combination of surgical thrombectomy and regional thrombolysis with rTPA could offer a feasible therapeutic option for selected patients with acute prehepatic portal vein thrombosis.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Faculty Institutions > Teaching Staff, Faculty of Medicine |
UniBE Contributor: |
Demertzis, Stefanos |
ISSN: |
0039-6060 |
ISBN: |
8128363 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 15:08 |
Last Modified: |
05 Dec 2022 14:20 |
PubMed ID: |
8128363 |
Web of Science ID: |
A1994NA20600017 |
URI: |
https://boris.unibe.ch/id/eprint/29696 (FactScience: 157860) |
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