Verstappen, Jochem; Katsaros, Christos; Torensma, Ruurd; Von den Hoff, Johannes W (2009). A functional model for adult stem cells in epithelial tissues. Wound repair and regeneration, 17(3), pp. 296-305. Hoboken, N.J.: Wiley-Blackwell 10.1111/j.1524-475X.2009.00497.x
Full text not available from this repository. (Request a copy)Tissue turnover, regeneration, and repair take place throughout life. Stem cells are key players in these processes. The characteristics and niches of the stem cell populations in different tissues, and even in related tissues, vary extensively. In this review, stem cell differentiation and stem cell contribution to tissue maintenance and regeneration is compared in the epithelia of the skin, the cornea, the lung, and the intestine. A hierarchical model for adult stem cells is proposed, based on the potency of stem cell subpopulations in a specific tissue. The potency is defined in terms of the maintenance, the repair, and the regeneration of the tissue. The niche supplies cues to maintain the specific stem cell potency.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Orthodontics |
UniBE Contributor: |
Katsaros, Christos |
ISSN: |
1067-1927 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Eveline Carmen Schuler |
Date Deposited: |
04 Oct 2013 15:11 |
Last Modified: |
05 Dec 2022 14:21 |
Publisher DOI: |
10.1111/j.1524-475X.2009.00497.x |
PubMed ID: |
19660036 |
Web of Science ID: |
000266244600003 |
URI: |
https://boris.unibe.ch/id/eprint/31059 (FactScience: 195459) |
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