Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients

Kreutziger, Janett; Wenzel, Volker; Kurz, Andrea; Constantinescu, Mihai Adrian (2009). Admission blood glucose is an independent predictive factor for hospital mortality in polytraumatised patients. Intensive care medicine, 35(7), pp. 1234-9. Berlin: Springer 10.1007/s00134-009-1446-z

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PURPOSE: The goal of this study was to analyse a possible association of admission blood glucose with hospital mortality of polytraumatised patients and to develop an outcome prediction model for this patient group. METHODS: The outcome of adult polytraumatised patients admitted to the University Hospital of Berne, Switzerland, between 2002 and 2004 with an ISS > or = 17, and more than one severely injured organ system was retrospectively analysed. RESULTS: The inclusion criteria were met by 555 patients, of which 108 (19.5%) died. Hyperglycaemia proved to be an independent predictor for hospital mortality (P < 0.0001), following multiple regression analysis. After inclusion of admission blood glucose, the calculated mortality prediction model performed better than currently described models (P < 0.0001, AUC 0.924). CONCLUSION: In this retrospective, single-centre study in polytraumatised patients, admission blood glucose proved to be an independent predictor of hospital mortality following regression analysis controlling for age, gender, injury severity and other laboratory parameters. A reliable admission blood glucose-based mortality prediction model for polytraumatised patients could be established. This observation may be helpful in improving the precision of future outcome prediction models for polytraumatised patients. These observations warrant further prospective evaluation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery

UniBE Contributor:

Constantinescu, Mihai Adrian

ISSN:

0342-4642

Publisher:

Springer

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 15:11

Last Modified:

05 Dec 2022 14:22

Publisher DOI:

10.1007/s00134-009-1446-z

PubMed ID:

19238355

Web of Science ID:

000267220800011

BORIS DOI:

10.48350/31450

URI:

https://boris.unibe.ch/id/eprint/31450 (FactScience: 196015)

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