Nisa, Lluis; Khanfir, Kaouthar; Giger, Roland (2013). Recurrence due to neoplastic seeding in head and neck cancer: report of two cases and review of the literature. Tumori, 99(4), e144-e147. Il Pensiero Scientifico Editore 10.1700/1361.15112
Full text not available from this repository. (Request a copy)AIMS AND BACKGROUND
Tumor progression due to seeding of tumor cells after definitive treatment for squamous cell carcinomas of the head and neck is an uncommon condition that can considerably worsen the outcome of patients with head and neck cancer.
METHODS AND STUDY DESIGN
We report two cases of recurrence due to neoplastic seeding from oropharyngeal and oral cancer, respectively. We performed a literature review with MEDLINE as the main search engine.
RESULTS
Seeding was found to occur most often in tracheotomy scars and gastrostomy sites. The oral cavity, hypopharynx and oropharynx were the primary sites in most cases, and advanced tumor stage seemed to be a risk factor for seeding. Treatment options include salvage surgery, which requires thorough resections, radiotherapy when possible, and palliative management. The prognosis of such events is poor.
CONCLUSION
Although neoplastic seeding is a well-known phenomenon in cancer surgery, many questions remain unanswered, especially regarding preventive measures and management strategies.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) |
UniBE Contributor: |
Nisa, Lluis, Giger, Roland |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2038-2529 |
Publisher: |
Il Pensiero Scientifico Editore |
Language: |
Italiano |
Submitter: |
Lilian Tschan |
Date Deposited: |
07 Mar 2014 12:09 |
Last Modified: |
05 Dec 2022 14:29 |
Publisher DOI: |
10.1700/1361.15112 |
PubMed ID: |
24326849 |
URI: |
https://boris.unibe.ch/id/eprint/43448 |
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