Ocak, Meltem; Helbok, Anna; Rangger, Christine; Peitl, Petra Kolenc; Nock, Berthold A; Morelli, Giancarlo; Eek, Annemarie; Sosabowski, Jane K; Breeman, Wout A P; Reubi, Jean-Claude; Decristoforo, Clemens (2011). Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1426-35. Berlin: Springer 10.1007/s00259-011-1818-9
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Ocak2011_Article_ComparisonOfBiologicalStabilit.pdf - Published Version Available under License Publisher holds Copyright. Download (1MB) | Preview |
Stability of radiolabelled cholecystokinin 2 (CCK2) receptor targeting peptides has been a major limitation in the use of such radiopharmaceuticals especially for targeted radionuclide therapy applications, e.g. for treatment of medullary thyroid carcinoma (MTC). The purpose of this study was to compare the in vitro stability of a series of peptides binding to the CCK2 receptor [selected as part of the COST Action on Targeted Radionuclide Therapy (BM0607)] and to identify major cleavage sites.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Reubi-Kattenbusch, Jean-Claude |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1619-7070 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:18 |
Last Modified: |
05 Dec 2022 14:05 |
Publisher DOI: |
10.1007/s00259-011-1818-9 |
PubMed ID: |
21528387 |
Web of Science ID: |
000292272700004 |
BORIS DOI: |
10.48350/5559 |
URI: |
https://boris.unibe.ch/id/eprint/5559 (FactScience: 210313) |
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