Méan, M; Limacher, A; Kahn, S R; Aujesky, D (2014). The VEINES-QOL/Sym questionnaire is a reliable and valid disease-specific quality of life measure for deep vein thrombosis in elderly patients. Quality of life research, 23(9), pp. 2463-2471. Springer 10.1007/s11136-014-0704-x
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PURPOSE
To prospectively evaluate the psychometric properties of the Venous Insufficiency Epidemiological and Economic Study (VEINES-QOL/Sym) questionnaire, an instrument to measure disease-specific quality of life and symptoms in elderly patients with deep vein thrombosis (DVT), and to validate a German version of the questionnaire.
METHODS
In a prospective multicenter cohort study of patients aged ≥ 65 years with acute venous thromboembolism, we used standard psychometric tests and criteria to evaluate the reliability, validity, and responsiveness of the VEINES-QOL/Sym in patients with acute symptomatic DVT. We also performed an exploratory factor analysis.
RESULTS
Overall, 352 French- and German-speaking patients were enrolled (response rate of 87 %). Both language versions of the VEINES-QOL/Sym showed good acceptability (missing data, floor and ceiling effects), reliability (internal consistency, item-total and inter-item correlations), validity (convergent, discriminant, known-groups differences), and responsiveness to clinical change over time in elderly patients with DVT. The exploratory factor analysis of the VEINES-QOL/Sym suggested three underlying dimensions: limitations in daily activities, DVT-related symptoms, and psychological impact.
CONCLUSIONS
The VEINES-QOL/Sym questionnaire is a practical, reliable, valid, and responsive instrument to measure quality of life and symptoms in elderly patients with DVT and can be used with confidence in prospective studies to measure outcomes in such patients.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine 04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR) |
UniBE Contributor: |
Méan Pascual, Marie, Limacher, Andreas, Aujesky, Drahomir |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0962-9343 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Doris Kopp Heim |
Date Deposited: |
03 Feb 2015 14:05 |
Last Modified: |
20 Feb 2024 14:17 |
Publisher DOI: |
10.1007/s11136-014-0704-x |
PubMed ID: |
24791928 |
BORIS DOI: |
10.7892/boris.62336 |
URI: |
https://boris.unibe.ch/id/eprint/62336 |
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