Novak, Urban; Basso, Katia; Pasqualucci, Laura; Dalla-Favera, Riccardo; Bhagat, Govind (2011). Genomic analysis of non-splenic marginal zone lymphomas (MZL) indicates similarities between nodal and extranodal MZL and supports their derivation from memory B-cells. British journal of haematology, 155(3), pp. 362-5. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2011.08841.x
Full text not available from this repository. (Request a copy)Three distinct categories of marginal zone lymphomas (MZLs) are currently recognized, principally based on their site of occurrence. They are thought to represent unique entities, but the relationship of one subtype with another is poorly understood. We investigated 17 non-splenic MZLs (seven nodal, 10 extranodal) by gene expression profiling to distinguish between subtypes and determine their cell of origin. Our findings suggest biological inter-relatedness of these entities despite occurrence at different locations and associations with possibly different aetiologies. Furthermore, the expression profiles of non-splenic MZL were similar to memory B cells.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology |
UniBE Contributor: |
Novak, Urban |
ISSN: |
0007-1048 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:20 |
Last Modified: |
05 Dec 2022 14:05 |
Publisher DOI: |
10.1111/j.1365-2141.2011.08841.x |
PubMed ID: |
21883140 |
Web of Science ID: |
000296063700008 |
URI: |
https://boris.unibe.ch/id/eprint/6480 (FactScience: 211452) |
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