Independence Day for IgA

Macpherson, Andrew; McCoy, Kathleen (2015). Independence Day for IgA. Immunity, 43(3), pp. 416-418. Cell Press 10.1016/j.immuni.2015.08.024

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IgA is induced through T-cell-dependent and -independent pathways. In this issue, Bunker et al. (2015) now show that the T-cell-independent pathway is sufficient to coat most small intestinal microbes specifically, and Fransen et al. (2015) find that IgA coating promotes uptake of microbes into Peyer's patches and drives further induction in a positive-feedback loop.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie

UniBE Contributor:

Macpherson, Andrew, McCoy, Kathleen

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1074-7613

Publisher:

Cell Press

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

30 Mar 2016 09:22

Last Modified:

05 Dec 2022 14:52

Publisher DOI:

10.1016/j.immuni.2015.08.024

PubMed ID:

26377894

BORIS DOI:

10.7892/boris.77490

URI:

https://boris.unibe.ch/id/eprint/77490

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