Detection and Differentiation of Intraretinal Hemorrhage in Spectral Domain Optical Coherence Tomography.

Munk, Marion R; Dunavoelgyi, Roman; Baratsits, Magdalena; Matt, Gerlinde; Montuoro, Alessio; Buehl, Wolf; Schmidt-Erfurth, Ursula; Sacu, Stefan (2014). Detection and Differentiation of Intraretinal Hemorrhage in Spectral Domain Optical Coherence Tomography. Current eye research, 40(10), pp. 1046-1054. Informa Healthcare 10.3109/02713683.2014.971931

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PURPOSE

The purpose of this study was to classify and detect intraretinal hemorrhage (IRH) in spectral domain optical coherence tomography (SD-OCT).

METHODS

Initially the presentation of IRH in BRVO-patients in SD-OCT was described by one reader comparing color-fundus (CF) and SD-OCT using dedicated software. Based on these established characteristics, the presence and the severity of IRH in SD-OCT and CF were assessed by two other masked readers and the inter-device and the inter-observer agreement were evaluated. Further the area of IRH was compared.

RESULTS

About 895 single B-scans of 24 eyes were analyzed. About 61% of SD-OCT scans and 46% of the CF-images were graded for the presence of IRH (concordance: 73%, inter-device agreement: k = 0.5). However, subdivided into previously established severity levels of dense (CF: 21.3% versus SD-OCT: 34.7%, k = 0.2), flame-like (CF: 15.5% versus SD-OCT: 45.5%, k = 0.3), and dot-like (CF: 32% versus SD-OCT: 24.4%, k = 0.2) IRH, the inter-device agreement was weak. The inter-observer agreement was strong with k = 0.9 for SD-OCT and k = 0.8 for CF. The mean area of IRH detected on SD-OCT was significantly greater than on CF (SD-OCT: 11.5 ± 4.3 mm(2) versus CF: 8.1 ± 5.5 mm(2), p = 0.008).

CONCLUSIONS

IRH seems to be detectable on SD-OCT; however, the previously established severity grading agreed weakly with that assessed by CF.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0271-3683

Publisher:

Informa Healthcare

Language:

English

Submitter:

Marion Munk

Date Deposited:

22 Jun 2016 18:00

Last Modified:

22 Jun 2016 18:00

Publisher DOI:

10.3109/02713683.2014.971931

PubMed ID:

25329527

Uncontrolled Keywords:

Imaging, intraretinal blood, intraretinal hemorrhage, multimodal imaging, optical coherence tomography, retinal vein occlusion

URI:

https://boris.unibe.ch/id/eprint/83445

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