Vyborna, Yuliia; Häner, Robert (15 September 2016). DNA-grafted supramolecular polymers: self-assembly, dynamics and potential applications (Unpublished). In: SCS Fall Meeting 2016. Zurich.
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The unique self-recognition properties of oligonucleotides laid the foundation of modern DNA nanotechnology. Over the last two decades, man-made DNA assemblies led to the development of numerous biocompatible functional materials, including drug carriers, nanorobots, and scaffolding platforms. A standard toolbox of building blocks used by chemists in the field is largely limited to four units – A, G, C, T. To further develop the functional potential of synthetic DNA systems, the use of DNA-chromophore conjugates emerges as an exciting approach. Following our previous findings, we demonstrate herein the pathway complexity in a temperature-induced self-assembly of the DNA-pyrene oligomers. Thermodynamically favoured DNA-grafted supramolecular polymers assemble into metastable networks through hybridization between DNA sticky ends followed by the subsequent re-assembly into individual DNA-grafted polymers through monomer exchange. Such systems become increasingly important for the creation of dynamic and stimuli-responsible materials targeting various applications such as delivery and precise scaffolding.
Item Type: |
Conference or Workshop Item (Poster) |
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Division/Institute: |
08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Vyborna, Yuliia, Häner, Robert |
Subjects: |
500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
Language: |
English |
Submitter: |
Yuliia Vyborna |
Date Deposited: |
30 Sep 2016 13:16 |
Last Modified: |
05 Dec 2022 14:59 |
BORIS DOI: |
10.7892/boris.88802 |
URI: |
https://boris.unibe.ch/id/eprint/88802 |
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