Di Mario, Carlo; Serruys, Patrick W; Silber, Sigmund; Lu, Shuzheng; Wang, Weimin; Widimský, Petr; Xu, Bo; Windecker, Stephan (2016). Long-term outcomes after Resolute zotarolimus-eluting stent implantation in patients with ST-segment elevation acute myocardial infarction: insights from the RESOLUTE All Comers Trial and the RESOLUTE Global Clinical Trial Program. EuroIntervention, 12(10), pp. 1207-1214. Europa Digital & Publishing 10.4244/EIJV12I10A199
Full text not available from this repository. (Request a copy)AIMS
We examined long-term outcomes after implantation of the Resolute zotarolimus-eluting stent (R-ZES) in ST-segment elevation acute myocardial infarction (STEMI) patients.
METHODS AND RESULTS
We compared long-term outcomes of STEMI patients undergoing primary angioplasty <12 hours from symptom onset who were randomised to the R-ZES (n=122) or the everolimus-eluting stent (EES, n=158) in the RESOLUTE All Comers Trial after propensity score adjustment. The five-year cumulative incidence of target lesion failure (TLF) was 7.6% versus 10.4% among patients treated with R-ZES versus EES, respectively, (adjusted p=0.304), and comprised clinically driven target lesion revascularisation (TLR, 2.5% versus 2.0%, adjusted p=0.766) and cardiac death/target vessel MI (5.1% versus 9.1%, adjusted p=0.123). The five-year cumulative incidence of stent thrombosis was 0.8% for R-ZES patients versus 1.3% for EES patients (adjusted p=0.868). In the RESOLUTE Global Clinical Trial Program, excluding RESOLUTE All Comers, the three-year cumulative incidence of TLF with R-ZES was 9.8% and comprised 7.0% clinically driven TLR and 4.5% cardiac death/target vessel MI.
CONCLUSIONS
Patients with STEMI who received R-ZES had excellent long-term clinical outcomes which were similar to those of patients who received EES.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Windecker, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1774-024X |
Publisher: |
Europa Digital & Publishing |
Language: |
English |
Submitter: |
Judith Liniger |
Date Deposited: |
19 Dec 2016 14:53 |
Last Modified: |
05 Dec 2022 15:00 |
Publisher DOI: |
10.4244/EIJV12I10A199 |
PubMed ID: |
27866129 |
URI: |
https://boris.unibe.ch/id/eprint/91068 |
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