Kindler, Eveline Patricia; Thiel, Volker Earl (2016). SARS-CoV and IFN: Too Little, Too Late. Cell host & microbe, 19(2), pp. 139-141. Cell Press 10.1016/j.chom.2016.01.012
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Dysregulated type I interferon (IFN-I) expression can lead to severe pathology and disease. In this issue of Cell Host & Microbe, Channappanavar et al. (2016) use a SARS-coronavirus animal model to describe how rapid and robust virus replication with delayed IFN-I can lead to lung immunopathology, with fatal outcomes.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Virology and Immunology 05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) |
UniBE Contributor: |
Kindler, Eveline Patricia, Thiel, Volker Earl |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 630 Agriculture |
ISSN: |
1931-3128 |
Publisher: |
Cell Press |
Language: |
English |
Submitter: |
Pamela Schumacher |
Date Deposited: |
21 Jul 2017 12:45 |
Last Modified: |
05 Dec 2022 15:03 |
Publisher DOI: |
10.1016/j.chom.2016.01.012 |
PubMed ID: |
26867172 |
BORIS DOI: |
10.7892/boris.96176 |
URI: |
https://boris.unibe.ch/id/eprint/96176 |
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