Deutsch, Urban

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Broggini, Thomas; Czabanka, Marcus; Piffko, Andras; Harms, Christoph; Hoffmann, Christian; Mrowka, Ralf; Wenke, Frank; Deutsch, Urban; Grötzinger, Carsten; Vajkoczy, Peter (2015). ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome. European spine journal, 24(10), pp. 2173-2181. Springer 10.1007/s00586-015-3811-7

Abadier, Michael Magdy Labib; Haghayegh Jahromi, Neda; Cardoso Alves, Ludmila; Boscacci, Rémy; Vestweber, Dietmar; Barnum, Scott; Deutsch, Urban; Engelhardt, Britta; Lyck, Ruth (2015). Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier. European journal of immunology, 45(4), pp. 1043-1058. Wiley-VCH 10.1002/eji.201445125


Liu, Ju; Deutsch, Urban; Fung, Iris; Lobe, Corrinne G (2014). Conditional and inducible transgene expression in endothelial and hematopoietic cells using Cre/loxP and tetracycline-off systems. Experimental and therapeutic medicine, 8(5), pp. 1351-1356. Spandidos Publ. 10.3892/etm.2014.1965

Liu, Ju; Dong, Fengyun; Fung, Iris; Chen, Edwin; Allen, Thaddeus D; Deutsch, Urban; Lobe, Corrinne G (2014). Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models. International journal of oncology, 45(5), pp. 1997-2004. Spandidos Publications 10.3892/ijo.2014.2626

Liu, Ju; Deutsch, Urban; Jeong, James; Lobe, Corrinne G (2014). Constitutive notch signaling in adult transgenic mice inhibits bFGF-induced angiogenesis and blocks ovarian follicle development. Genesis, 52(9), pp. 809-816. Wiley-Liss 10.1002/dvg.22790

Sathiyanadan, Karthik; Coisne, Caroline Marie; Enzmann, Gaby; Deutsch, Urban; Engelhardt, Britta (2014). PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE. European journal of immunology, 44(8), pp. 2287-2294. Wiley-VCH 10.1002/eji.201344214

Minten, Carsten; Alt, Carsten; Gentner, Melanie; Frei, Elisabeth; Deutsch, Urban; Lyck, Ruth; Schaeren-Wiemers, Nicole; Rot, Antal; Engelhardt, Britta (2014). DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation. Brain, 137(Pt 5), pp. 1454-1469. Oxford University Press 10.1093/brain/awu045


Ziegler, Tilman; Horstkotte, Jan; Schwab, Claudia; Pfetsch, Vanessa; Weinmann, Karolina; Dietzel, Steffen; Rohwedder, Ina; Hinkel, Rabea; Gross, Lisa; Lee, Seungmin; Hu, Junhao; Soehnlein, Oliver; Franz, Wolfgang M.; Sperandio, Markus; Pohl, Ulrich; Thomas, Markus; Weber, Christian; Augustin, Hellmut G.; Fässler, Reinhard; Deutsch, Urban; ... (2013). Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis. Journal of clinical investigation, 123(8), pp. 3436-3445. American Society for Clinical Investigation 10.1172/JCI66549


Wyss, Lena; Schäfer, Julia; Liebner, Stefan; Mittelbronn, Michel; Deutsch, Urban; Enzmann, Gaby; Adams, Ralf H.; Aurrand-Lions, Michel; Plate, Karl H.; Imhof, Beat A.; Engelhardt, Britta (2012). Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus. PLoS ONE, 7(9), e45619. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045619


Bill, Ruben; Döring, Axinia; Deutsch, Urban; Engelhardt, Britta (2011). PSGL-1 is dispensible for the development of active experimental autoimmune encephalomyelitis in SJL/J mice. Journal of neuroimmunology, 232(1-2), pp. 207-8. Amsterdam: Elsevier 10.1016/j.jneuroim.2010.10.008

Pfeiffer, Friederike; Schäfer, Julia; Lyck, Ruth; Makrides, Victoria; Brunner, Sarah; Schaeren-Wiemers, Nicole; Deutsch, Urban; Engelhardt, Britta (2011). Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis. Acta neuropathologica, 122(5), pp. 601-14. Berlin: Springer 10.1007/s00401-011-0883-2

Döring, Axinia; Pfeiffer, Friederike; Meier, Matthias; Dehouck, Bénédicte; Tauber, Silke; Deutsch, Urban; Engelhardt, Britta (2011). TET inducible expression of the α4β7-integrin ligand MAdCAM-1 on the blood-brain barrier does not influence the immunopathogenesis of experimental autoimmune encephalomyelitis. European journal of immunology, 41(3), pp. 813-21. Weinheim: Wiley-VCH 10.1002/eji.201040912


Chadjichristos, C E; Scheckenbach, K E L; van Veen, T A B; Richani Sarieddine, M Z; de Wit, C; Yang, Z; Roth, I; Bacchetta, M; Viswambharan, H; Foglia, B; Dudez, T; van Kempen, M J A; Coenjaerts, F E J; Miquerol, L; Deutsch, U; Jongsma, H J; Chanson, M; Kwak, B R (2010). Endothelial-specific deletion of connexin40 promotes atherosclerosis by increasing CD73-dependent leukocyte adhesion. Circulation, 121(1), pp. 123-31. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCULATIONAHA.109.867176

Pfister, Frederick; Wang, Yumei; Schreiter, Kay; vom Hagen, Franziska; Altvater, Karin; Hoffmann, Sigrid; Deutsch, Urban; Hammes, Hans-Peter; Feng, Yuxi (2010). Retinal overexpression of angiopoietin-2 mimics diabetic retinopathy and enhances vascular damages in hyperglycemia. Acta diabetologica, 47(1), pp. 59-64. Milano: Springer 10.1007/s00592-009-0099-2

Boscacci, Rémy T; Pfeiffer, Friederike; Gollmer, Kathrin; Checa Sevilla, Ana Isabel; Martin, Ana Maria; Soriano, Silvia Fernandez; Natale, Daniela; Henrickson, Sarah; von Andrian, Ulrich H; Fukui, Yoshinori; Mellado, Mario; Deutsch, Urban; Engelhardt, Britta; Stein, Jens V (2010). Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing. Blood, 116(6), pp. 915-25. Washington, D.C.: American Society of Hematology 10.1182/blood-2009-11-254334

Steiner, Oliver; Coisne, Caroline; Cecchelli, Roméo; Boscacci, Rémy; Deutsch, Urban; Engelhardt, Britta; Lyck, Ruth (2010). Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium. Journal of immunology, 185(8), pp. 4846-55. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0903732

Wang, Yingdi; Nakayama, Masanori; Pitulescu, Mara E; Schmidt, Tim S; Bochenek, Magdalena L; Sakakibara, Akira; Adams, Susanne; Davy, Alice; Deutsch, Urban; Lüthi, Urs; Barberis, Alcide; Benjamin, Laura E; Mäkinen, Taija; Nobes, Catherine D; Adams, Ralf H (2010). Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature, 465(7297), pp. 483-6. London: Macmillan Journals Ltd. 10.1038/nature09002


Feng, Yuxi; Vom Hagen, Franziska; Wang, Yumei; Beck, Susanne; Schreiter, Kay; Pfister, Frederick; Hoffmann, Sigrid; Wagner, Patrick; Seeliger, Mathias; Molema, Grietje; Deutsch, Urban; Hammes, Hans-Peter (2009). The absence of angiopoietin-2 leads to abnormal vascular maturation and persistent proliferative retinopathy. Thrombosis and haemostasis, 102(1), pp. 120-30. Stuttgart: Schattauer 10.1160/TH08-09-0567

Feng, Yuxi; Wang, Yumei; Pfister, Frederick; Hillebrands, Jan-Luuk; Deutsch, Urban; Hammes, Hans-Peter (2009). Decreased hypoxia-induced neovascularization in angiopoietin-2 heterozygous knockout mouse through reduced MMP activity. Cellular physiology and biochemistry, 23(4-6), pp. 277-84. Basel: Karger 10.1159/000218174

Winderlich, Mark; Keller, Linda; Cagna, Giuseppe; Broermann, Andre; Kamenyeva, Olena; Kiefer, Friedemann; Deutsch, Urban; Nottebaum, Astrid F; Vestweber, Dietmar (2009). VE-PTP controls blood vessel development by balancing Tie-2 activity. Journal of cell biology, 185(4), pp. 657-71. New York, N.Y.: Rockefeller Institute Press 10.1083/jcb.200811159

Noell, Susan; Fallier-Becker, Petra; Deutsch, Urban; Mack, Andreas F; Wolburg, Hartwig (2009). Agrin defines polarized distribution of orthogonal arrays of particles in astrocytes. Cell and tissue research, 337(2), pp. 185-95. Heidelberg: Springer 10.1007/s00441-009-0812-z

Kokai, Enikö; Voss, Florian; Fleischer, Frank; Kempe, Sybille; Marinkovic, Dragan; Wolburg, Hartwig; Leithäuser, Frank; Schmidt, Volker; Deutsch, Urban; Wirth, Thomas (2009). Myc regulates embryonic vascular permeability and remodeling. Circulation research, 104(10), pp. 1151-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.108.191460

Reiss, Yvonne; Knedla, Anette; Tal, Andrea O; Schmidt, Mirko H H; Jugold, Manfred; Kiessling, Fabian; Burger, Angelika M; Wolburg, Hartwig; Deutsch, Urban; Plate, Karl H (2009). Switching of vascular phenotypes within a murine breast cancer model induced by angiopoietin-2. Journal of pathology, 217(4), pp. 571-80. Chichester: Wiley 10.1002/path.2484


Dufourcq, Pascale; Leroux, Lionel; Ezan, Jérome; Descamps, Betty; Lamazière, Jean-Marie Daniel; Costet, Pierre; Basoni, Caroline; Moreau, Catherine; Deutsch, Urban; Couffinhal, Thierry; Duplàa, Cécile (2008). Regulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation. American journal of pathology, 172(1), pp. 37-49. New York, N.Y.: Elsevier 10.2353/ajpath.2008.070130

Deutsch, Urban; Schlaeger, Thorsten M; Dehouck, Bénédicte; Döring, Axinia; Tauber, Silke; Risau, Werner; Engelhardt, Britta (2008). Inducible endothelial cell-specific gene expression in transgenic mouse embryos and adult mice. Experimental cell research, 314(6), pp. 1202-16. San Diego, Calif.: Elsevier 10.1016/j.yexcr.2007.12.026

Feng, Yuxi; Pfister, Frederick; Schreiter, Kay; Wang, Yumei; Stock, Oliver; Vom Hagen, Franziska; Wolburg, Hartwig; Hoffmann, Sigrid; Deutsch, Urban; Hammes, Hans-Peter (2008). Angiopoietin-2 deficiency decelerates age-dependent vascular changes in the mouse retina. Cellular physiology and biochemistry, 21(1-3), pp. 129-36. Basel: Karger 10.1159/000113755

Swendeman, Steven; Mendelson, Karen; Weskamp, Gisela; Horiuchi, Keisuke; Deutsch, Urban; Scherle, Peggy; Hooper, Andrea; Rafii, Shahin; Blobel, Carl P (2008). VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling. Circulation research, 103(9), pp. 916-8. Baltimore, Md.: Lippincott Williams & Wilkins 10.1161/CIRCRESAHA.108.184416

Leen, Laetitia Lam Shang; Filipe, Cédric; Billon, Audrey; Garmy-Susini, Barbara; Jalvy, Sandra; Robbesyn, Fanny; Daret, Danièle; Allières, Cécile; Rittling, Susan R; Werner, Nikos; Nickenig, Georg; Deutsch, Urban; Duplàa, Cécile; Dufourcq, Pascale; Lenfant, Françoise; Desgranges, Claude; Arnal, Jean-François; Gadeau, Alain-Pierre (2008). Estrogen-stimulated endothelial repair requires osteopontin. Arteriosclerosis, thrombosis, and vascular biology, 28(12), pp. 2131-6. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1161/ATVBAHA.108.167965

Pfister, Frederick; Feng, Yuxi; vom Hagen, Franziska; Hoffmann, Sigrid; Molema, Grietje; Hillebrands, Jan-Luuk; Shani, Moshe; Deutsch, Urban; Hammes, Hans-Peter (2008). Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy. Diabetes, 57(9), pp. 2495-502. Alexandria, Va.: American Diabetes Association 10.2337/db08-0325

Saharinen, Pipsa; Eklund, Lauri; Miettinen, Juho; Wirkkala, Riikka; Anisimov, Andrey; Winderlich, Mark; Nottebaum, Astrid; Vestweber, Dietmar; Deutsch, Urban; Koh, Gou Young; Olsen, Bjorn R; Alitalo, Kari (2008). Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nature cell biology, 10(5), pp. 527-37. London: Nature Publishing Group 10.1038/ncb1715


Döring, Axinia; Wild, Martin; Vestweber, Dietmar; Deutsch, Urban; Engelhardt, Britta (2007). E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. Journal of immunology, 179(12), pp. 8470-9. Bethesda, Md.: American Association of Immunologists

Yuan, Hai Tao; Venkatesha, Shivalingappa; Chan, Barden; Deutsch, Urban; Mammoto, Tadanori; Sukhatme, Vikas P; Woolf, Adrian S; Karumanchi, S Ananth (2007). Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival. FASEB journal, 21(12), pp. 3171-83. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.07-8487com

Feng, Yuxi; vom Hagen, Franziska; Pfister, Frederick; Djokic, Snezana; Hoffmann, Sigrid; Back, Walter; Wagner, Patrick; Lin, Jihong; Deutsch, Urban; Hammes, Hans-Peter (2007). Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression. Thrombosis and haemostasis, 97(1), pp. 99-108. Stuttgart: Schattauer 10.1160/TH06-05-0277


Bäumer, Sebastian; Keller, Linda; Holtmann, Astrid; Funke, Ruth; August, Benjamin; Gamp, Alexander; Wolburg, Hartwig; Wolburg-Buchholz, Karen; Deutsch, Urban; Vestweber, Dietmar (2006). Vascular endothelial cell-specific phosphotyrosine phosphatase (VE-PTP) activity is required for blood vessel development. Blood, 107(12), pp. 4754-62. Washington, D.C.: American Society of Hematology 10.1182/blood-2006-01-0141


vom Hagen, F; Feng, Y; Hillenbrand, A; Hoffmann, S; Shani, M; Deutsch, U; Hammes, HP (2005). Early loss of arteriolar smooth muscle cells: more than just a pericyte loss in diabetic retinopathy. Experimental and clinical endocrinology & diabetes, 113(10), pp. 573-6. Stuttgart: Thieme 10.1055/s-2005-872894

Hoffmann, J; Feng, Y; vom Hagen, F; Hillenbrand, A; Lin, J; Erber, R; Vajkoczy, P; Gourzoulidou, E; Waldmann, H; Giannis, A; Wolburg, H; Shani, M; Jaeger, V; Weich, HA; Preissner, KT; Hoffmann, S; Deutsch, U; Hammes, HP (2005). Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity. FASEB journal, 14(19), pp. 2035-6. Bethesda, Md.: Federation of American Societies for Experimental Biology 10.1096/fj.04-2109fje

May, T; Mueller, PP; Weich, H; Froese, N; Deutsch, U; Wirth, D; Kröger, A; Hauser, H (2005). Establishment of murine cell lines by constitutive and conditional immortalization. Journal of biotechnology, 120(1), pp. 99-110. Amsterdam: Elsevier 10.1016/j.jbiotec.2005.03.027


Ivkovic, S; Deutsch, U; Silberbach, A; Walraph, E; Mannel, M (2004). Dietary supplementation with the tribomechanically activated zeolite clinoptilolite in immunodeficiency: effects on the immune system. Advances in therapy, 21(2), pp. 135-147. Springer 10.1007/BF02850340

Deutsch, U (2004). Semaphorins guide PerPlexeD endothelial cells. Developmental cell, 7(1), pp. 1-2. Cambridge, Mass.: Cell Press 10.1016/j.devcel.2004.06.012

Hammes, HP; Lin, J; Wagner, P; Feng, Y; Vom Hagen, F; Krzizok, T; Renner, O; Breier, G; Brownlee, M; Deutsch, U (2004). Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy. Diabetes, 53(4), pp. 1104-10. Alexandria, Va.: American Diabetes Association 10.2337/diabetes.53.4.1104


Fiedler, U; Krissl, T; Koidl, S; Weiss, C; Koblizek, T; Deutsch, U; Martiny-Baron, G; Marmé, D; Augustin, HG (2003). Angiopoietin-1 and angiopoietin-2 share the same binding domains in the Tie-2 receptor involving the first Ig-like loop and the epidermal growth factor-like repeats. Journal of biological chemistry, 3(278), pp. 1721-7. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M208550200


Hammes, HP; Lin, J; Renner, O; Shani, M; Lundqvist, A; Betsholtz, C; Brownlee, M; Deutsch, U (2002). Pericytes and the pathogenesis of diabetic retinopathy. Diabetes, 51(10), pp. 3107-12. Alexandria, Va.: American Diabetes Association 10.2337/diabetes.51.10.3107

Nawroth, R; Poell, G; Ranft, A; Kloep, S; Samulowitz, U; Fachinger, G; Golding, M; Shima, DT; Deutsch, U; Vestweber, D (2002). VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts. EMBO journal, 18(21), pp. 4885-95. London: Nature Publishing Group 10.1093/emboj/cdf497

Willecke, K; Eiberger, J; Degen, J; Eckardt, D; Romualdi, A; Güldenagel, M; Deutsch, U; Söhl, G (2002). Structural and functional diversity of connexin genes in the mouse and human genome. Biological chemistry, 5(383), pp. 725-37. Berlin: De Gruyter 10.1515/BC.2002.076

Palmer, A; Zimmer, M; Erdmann, KS; Eulenburg, V; Porthin, A; Heumann, R; Deutsch, U; Klein, R (2002). EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Molecular cell, 4(9), pp. 725-37. Cambridge, Mass.: Cell Press 10.1016/S1097-2765(02)00488-4


Eiberger, J; Degen, J; Romualdi, A; Deutsch, U; Willecke, K; Söhl, G (2001). Connexin genes in the mouse and human genome. Cell communication & adhesion, 8(4-6), pp. 163-5. Basingstoke, UK: Taylor & Francis 10.3109/15419060109080717

Adams, RH; Diella, F; Hennig, S; Helmbacher, F; Deutsch, U; Klein, R (2001). The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell, 104(1), pp. 57-69. Cambridge, Mass.: Cell Press 10.1016/S0092-8674(01)00191-X

Theis, M; de Wit, C; Schlaeger, TM; Eckardt, D; Krüger, O; Döring, B; Risau, W; Deutsch, U; Pohl, U; Willecke, K (2001). Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene. Genesis, 29(1), pp. 1-13. Hoboken, N.J.: Wiley-Liss 10.1002/1526-968X(200101)29:1<1::AID-GENE1000>3.0.CO;2-0


Fachinger, G; Deutsch, U; Risau, W (1999). Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2. Oncogene, 43(18), pp. 5948-53. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1202992

Adams, RH; Wilkinson, GA; Weiss, C; Diella, F; Gale, NW; Deutsch, U; Risau, W; Klein, R (1999). Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes & development, 13(3), pp. 295-306. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press 10.1101/gad.13.3.295


Reiss, Y; Hoch, G; Deutsch, U; Engelhardt, B (1998). T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells. European journal of immunology, 28(10), pp. 3086-99. Weinheim: Wiley-VCH 10.1002/(SICI)1521-4141(199810)28:10<3086::AID-IMMU3086>3.0.CO;2-Z

Knies, UE; Behrensdorf, HA; Mitchell, CA; Deutsch, U; Risau, W; Drexler, HC; Clauss, M (1998). Regulation of endothelial monocyte-activating polypeptide II release by apoptosis. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 95(21), pp. 12322-7. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.95.21.12322

Koblizek, TI; Weiss, C; Yancopoulos, GD; Deutsch, U; Risau, W (1998). Angiopoietin-1 induces sprouting angiogenesis in vitro. Current Biology, 9(8), pp. 529-32. Cambridge, Mass.: Cell Press 10.1016/S0960-9822(98)70205-2


Mayr, T; Deutsch, U; Kühl, M; Drexler, HC; Lottspeich, F; Deutzmann, R; Wedlich, D; Risau, W (1997). Fritz: a secreted frizzled-related protein that inhibits Wnt activity. Mechanisms of development, 63(1), pp. 109-25. Shannon: Elsevier 10.1016/S0925-4773(97)00035-X

Schlaeger, TM; Bartunkova, S; Lawitts, JA; Teichmann, G; Risau, W; Deutsch, U; Sato, TN (1997). Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 94(7), pp. 3058-63. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.94.7.3058

Koblizek, TI; Runting, AS; Stacker, SA; Wilks, AF; Risau, W; Deutsch, U (1997). Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues. European journal of biochemistry, 244(3), pp. 774-9. Cambridge: Blackwell Science 10.1111/j.1432-1033.1997.00774.x

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