Heller, Manfred

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Braga, Sophie Marie-Pierre; Buchs, Natasha; Iacovache, Mircea Ioan; Zuber, Benoît; Jackson, Christopher; Heller, Manfred (2016). Robust Label-free, Quantitative Profiling of Circulating Plasma Microparticle (MP) Associated Proteins. Molecular & cellular proteomics, 15(12), pp. 3640-3652. American Society for Biochemistry and Molecular Biology 10.1074/mcp.M116.060491

Ruegsegger, Céline; Maharjan, Niran; Goswami, Anand; Filézac de l’Etang, Audrey; Weis, Joachim; Troost, Dirk; Heller, Manfred; Gut, Heinz; Saxena, Smita (2016). Aberrant association of misfolded SOD1 with Na+/K+ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS. Acta neuropathologica, 131(3), pp. 427-451. Springer 10.1007/s00401-015-1510-4


Petrovic, Marian; Simillion, Cedric André Marie; Kruzliak, Peter; Sabo, Jan; Heller, Manfred (2015). Doxorubicin Affects Expression of Proteins of Neuronal Pathways in MCF-7 Breast Cancer Cells. Cancer genomics & proteomics, 12(6), pp. 347-358. International Institute of Anticancer Research

Raczynska, Katarzyna Dorota; Ruepp, Marc-David; Brzek, Aleksandra; Reber, Stefan; Romeo, Valentina; Rindlisbacher, Barbara; Heller, Manfred; Szweykowska-Kulinska, Zofia; Jarmolowski, Artur; Schümperli, Daniel (2015). FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors. Nucleic acids research, 43(20), pp. 9711-9728. Information Retrieval Ltd. 10.1093/nar/gkv794

Leuenberger, Michele; Jack, Thomas; Ruepp, Marc-David; Lagache, Sophie; Heller, Manfred; Mühlemann, Oliver; Thompson, Andrew J.; Lochner, Martin (15 June 2015). Synthesis of photo-crosslinking probes and their application for the site-selective chemical modification of the 5-HT3 receptor (Unpublished). In: Challenges in Chemical Biology (ISACS16). Book of Abstracts. ETH Zürich, Hönggerberg, Switzerland. 15.06.-18.06.2015.

Stettler, Karin; Li, Xiaoming; Sandrock, Björn; Braga, Sophie Marie-Pierre; Heller, Manfred; Dümbgen, Lutz; Suter, Beat (2015). A Drosophila XPD model links cell cycle coordination with neuro-development and suggests links to cancer. Disease models & mechanisms, 8(1), pp. 81-91. Company of Biologists Ltd. 10.1242/dmm.016907

Naguleswaran, Arunasalam; Gunasekera, Kapila; Schimanski, Bernd; Heller, Manfred; Hemphill, Andrew; Ochsenreiter, Torsten; Roditi, Isabel (2015). Trypanosoma brucei RRM1 is a nuclear RNA-binding protein and modulator of chromatin structure. mBio, 6(2), e00114. American Society for Microbiology 10.1128/mBio.00114-15


Zysset-Burri, Denise Corinne; Müller, Norbert; Beuret, Christian; Heller, Manfred; Schürch, Nadia; Gottstein, Bruno; Wittwer, Matthias (2014). Genome-wide identification of pathogenicity factors of the free-living amoeba Naegleria fowleri. BMC Genomics, 15, p. 496. BioMed Central 10.1186/1471-2164-15-496

Engel, Hans Jürg; Mika, Moana; Denapaite, Dalia; Hakenbeck, Regine; Mühlemann, Kathrin; Heller, Manfred; Hathaway, Lucy Jane; Hilty, Markus (2014). A low affinity penicillin-binding protein 2x is required for heteroresistance in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 58(7), pp. 3934-3941. American Society for Microbiology 10.1128/AAC.02547-14

Hathaway, Lucy J.; Bättig, Patrick; Reber, Sandra; Rotzetter, Jeannine Ursula; Aebi, Susanne; Hauser, Christoph; Heller, Manfred; Kadioglu, Aras; Mühlemann, Kathrin (2014). Streptococcus pneumoniae detects and responds to foreign bacterial peptide fragments in its environment. Open Biology, 4(130224), p. 130224. The Royal Society Publishing 10.1098/rsob.130224

Cristodero, Marina; Schimanski, Bernd; Heller, Manfred; Roditi, Isabel (2014). Functional characterization of the trypanosome translational repressor SCD6. Biochemical journal, 457(1), pp. 57-67. Portland Press 10.1042/BJ20130747


Schumann Burkard, Gabriela; Käser, Sandro; de Araújo, Patricia; Schimanski, Bernd; Naguleswaran, Arunasalam; Knüsel, Sebastian; Heller, Manfred; Roditi, Isabel (2013). Nucleolar proteins regulate stage-specific gene expression and ribosomal RNA maturation in Trypanosoma brucei. Molecular microbiology, 88(4), pp. 827-840. Blackwell Science 10.1111/mmi.12227

Vanden Bergh, Philippe; Heller, Manfred; Braga-Lagache, Sophie; Frey, Joachim (2013). The Aeromonas salmonicida subsp. salmonicida exoproteome: global analysis, moonlighting proteins and putative antigens for vaccination against furunculosis. Proteome Science, 11(1), p. 44. BioMed Central 10.1186/1477-5956-11-44

Vanden Bergh, Philippe; Heller, Manfred; Braga-Lagache, Sophie; Frey, Joachim (2013). The Aeromonas salmonicida subsp. salmonicida exoproteome: determination of the complete repertoire of Type-Three Secretion System effectors and identification of other virulence factors. Proteome Science, 11(1), p. 42. BioMed Central 10.1186/1477-5956-11-42


Gunasekera, Kapila; Wüthrich, Daniel; Braga-Lagache, Sophie; Heller, Manfred; Ochsenreiter, Torsten (2012). Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry. BMC Genomics, 13, p. 556. London: BioMed Central 10.1186/1471-2164-13-556

Al Kaabi, Ali; Traupe, Tobias; Stutz, Monika; Buchs, Natasha; Heller, Manfred (2012). Cause or effect of arteriogenesis: compositional alterations of microparticles from CAD patients undergoing external counterpulsation therapy. PLoS ONE, 7(10), e46822. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0046822

Eltschinger, Sandra; Greganova, Eva; Heller, Manfred; Bütikofer, Peter; Altmann, Michael (2012). Eukaryotic translation elongation factor 1A (eEF1A) domain I from S. cerevisiae is required but not sufficient for inter-species complementation. PLoS ONE, 7(7), e42338. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0042338


Mani, Jan; Güttinger, Andreas; Schimanski, Bernd; Heller, Manfred; Acosta-Serrano, Alvaro; Pescher, Pascale; Späth, Gerald; Roditi, Isabel (2011). Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery. PLoS ONE, 6(7), e22463. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0022463


Vincent, Bruno; Kaeslin, Martha; Roth, Thomas; Heller, Manfred; Poulain, Julie; Cousserans, François; Schaller, Johann; Poirié, Marylène; Lanzrein, Beatrice Constance; Drezen, Jean-Michel; Moreau, Sébastien JM (2010). The venom composition of the parasitic wasp Chelonus inanitus resolved by combined expressed sequence tags analysis and proteomic approach. BMC Genomics, 11(1), p. 693. London: BioMed Central 10.1186/1471-2164-11-693

Wetterwald, C; Roth, T; Kaeslin, M; Annaheim, M; Wespi, G; Heller, M; Mäser, P; Roditi, I; Pfister-Wilhelm, R; Bézier, A; Gyapay, G; Drezen, JM; Lanzrein, B (2010). Identification of bracovirus particle proteins and analysis of their transcript levels at the stage of virion formation. Journal of general virology, 91(10), pp. 2610-2619. Reading: Society for General Microbiology 10.1099/vir.0.022699-0

Greganova, E; Heller, M; Bütikofer, P (2010). A structural domain mediates attachment of ethanolamine phosphoglycerol to eukaryotic elongation factor 1A in Trypanosoma brucei. PLoS ONE, 5(3), e9486. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0009486


Da Silva-Azevedo, Luis; Jähne, Sebastian; Hoffmann, Christian; Stalder, Daniel; Heller, Manfred; Pries, Axel R; Zakrzewicz, Andreas; Baum, Oliver (2009). Up-regulation of the peroxiredoxin-6 related metabolism of reactive oxygen species in skeletal muscle of mice lacking neuronal nitric oxide synthase. Journal of physiology, 587(Pt 3), pp. 655-68. Oxford: Wiley-Blackwell 10.1113/jphysiol.2008.164947

Bézier, A; Annaheim, M; Herbinière, J; Wetterwald, C; Gyapay, G; Bernard-Samain, S; Wincker, P; Roditi, I; Heller, M; Belghazi, M; Pfister-Wilhelm, R; Periquet, G; Dupuy, C; Huguet, E; Volkoff, A.N.; Lanzrein, B; Drezen, J.M. (2009). Polydnaviruses of braconid wasps derive from an ancestral nudivirus. Science, 323(5916), pp. 926-930. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1166788

Koch, Rafael; Romana, Ledermann; Urwyler, Olivier; Heller, Manfred; Suter, Beat (2009). Systematic Functional Analysis of BicD Serine Phosphorylation and Intragenic Suppression of a Female Sterile Allele of BicD. PLoS ONE, 4(2), e4552. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004552


Ambort, Daniel; Stalder, Daniel; Lottaz, Daniel; Huguenin, Maya; Oneda, Beatrice; Heller, Manfred; Sterchi, Erwin E (2008). A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin. FEBS journal, 275(18), pp. 4490-509. Oxford: Wiley-Blackwell 10.1111/j.1742-4658.2008.06592.x

Stalder, Daniel; Haeberli, André; Heller, Manfred (2008). Evaluation of reproducibility of protein identification results after multidimensional human serum protein separation. Proteomics, 8(3), pp. 414-24. Weinheim: Wiley-VCH 10.1002/pmic.200700527

stalder, d; cung, t; gloeker, s; meier, p; schlappritzi, e; haeberli, a; marcovina, s; seiler, c; heller, m (2008). Apolipoprotein(a) Size and Lipoprotein(a) Concentrations in Patients with Good and Poor Coronary Collateral Flow an Interrelation Discovered by Proteomic Screening of Pooled Plasma Samples. Journal of proteomics & bioinformatics, 1, pp. 380-400. Dayton, Ohio: OMICS Publ.


Heller, Manfred; Schlappritzi, Evelyn; Stalder, Daniel; Nuoffer, Jean-Marc; Haeberli, André (2007). Compositional protein analysis of high density lipoproteins in hypercholesterolemia by shotgun LC-MS/MS and probabilistic peptide scoring. Molecular & cellular proteomics, 6(6), pp. 1059-72. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/mcp.M600326-MCP200

Schaub, Alexander; Wymann, Sandra; Heller, Manfred; Ghielmetti, Marco; Beleznay, Zsuzsanne; Stadler, Beda M; Bolli, Reinhard; Miescher, Sylvia (2007). Self-reactivity in the dimeric intravenous immunoglobulin fraction. Annals of the New York Academy of Sciences, 1110, pp. 681-693. Boston, Mass.: Blackwell 10.1196/annals.1423.071


Rentsch, Cyrill A; Cecchini, Marco G; Schwaninger, Ruth; Germann, Markus; Markwalder, Regula; Heller, Manfred; van der Pluijm, Gabri; Thalmann, George N; Wetterwald, Antoinette (2006). Differential expression of TGFbeta-stimulated clone 22 in normal prostate and prostate cancer. International journal of cancer, 118(4), pp. 899-906. Malden, Mass.: Wiley-Blackwell 10.1002/ijc.21449

Michel, Philippe E; Crettaz, David; Morier, Patrick; Heller, Manfred; Gallot, Denis; Tissot, Jean-Daniel; Reymond, Frédéric; Rossier, Joel S (2006). Proteome analysis of human plasma and amniotic fluid by Off-Gel isoelectric focusing followed by nano-LC-MS/MS. Electrophoresis, 27(5-6), pp. 1169-81. Weinheim: Wiley-VCH 10.1002/elps.200500680


Heller, Manfred; Stalder, Daniel; Schlappritzi, Evelyn; Hayn, Gertraud; Matter, Urs; Haeberli, André (2005). Mass spectrometry-based analytical tools for the molecular protein characterization of human plasma lipoproteins. Proteomics, 5(10), pp. 2619-30. Weinheim: Wiley-VCH 10.1002/pmic.200401233

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