Istrate, Alena

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2019

Istrate, Andrei; Johannsen, Silke; Istrate, Alena; Sigel, Roland K O; Leumann, Christian (2019). NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. Nucleic acids research, 47(9), pp. 4872-4882. Oxford University Press 10.1093/nar/gkz197

2017

Istrate, Alena; Katolik, Adam; Istrate, Andrei; Leumann, Christian (2017). 2′β-Fluoro-Tricyclo Nucleic Acids (2′F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation. Chemistry: a European journal, 23(43), pp. 10310-10318. Wiley 10.1002/chem.201701476

2016

Röthlisberger, Pascal; Istrate, Alena; Marcaida Lopez, M. J.; Visini, Ricardo; Stocker, Achim; Reymond, Jean-Louis; Leumann, Christian (2016). X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair. Chemical communications, 52(26), pp. 4749-4752. Royal Society of Chemistry 10.1039/c6cc00374e

Hari, Yvonne; Dugovic, Branislav; Istrate, Alena; Fignolé, Klavdja Annabel; Schürch, Stefan (2016). The Contribution of the Activation Entropy to the Gas-Phase Stability of Modified Nucleic Acid Duplexes. Journal of the American Society for Mass Spectrometry, 27(7), pp. 1186-1196. Springer 10.1007/s13361-016-1391-3

2015

Medvecky, Michal; Istrate, Alena; Leumann, Christian (2015). Synthesis and Properties of 6′-Fluoro-tricyclo-DNA. The Journal of organic chemistry, 80(7), pp. 3556-3565. American Chemical Society 10.1021/acs.joc.5b00184

Istrate, Alena; Medvecky, Michal; Leumann, Christian J. (2015). 2′-Fluorination of Tricyclo-DNA Controls Furanose Conformation and Increases RNA Affinity. Organic letters, 17(8), pp. 1950-1953. American Chemical Society 10.1021/acs.orglett.5b00662

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