Jakob, Stephan

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De Marchis, Gian Marco; Schaad, Chris; Fung, Christian; Beck, Jürgen; Gralla, Jan; Takala, Jukka; Jakob, Stephan (2017). Gender-related differences in aneurysmal subarachnoid hemorrhage: A hospital based study. Clinical neurology and neurosurgery, 157, pp. 82-87. Elsevier 10.1016/j.clineuro.2017.04.009

Glas, Michael; Frick, Tamara; Springe, Dirk; Putzu, Alessandro; Zürcher, Patrick; Grandgirard, Denis; Leib, Stephen; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2017). Neuroprotection with the P53-Inhibitor Pifithrin-μ After Cardiac Arrest in a Rodent Model. (In Press). Shock Lippincott Williams & Wilkins 10.1097/SHK.0000000000000917

Reintam Blaser, Annika; Starkopf, Joel; Alhazzani, Waleed; Berger, Mette M.; Casaer, Michael P.; Deane, Adam M.; Fruhwald, Sonja; Hiesmayr, Michael; Ichai, Carole; Jakob, Stephan; Loudet, Cecilia I.; Malbrain, Manu L. N. G.; Montejo González, Juan C.; Paugam-Burtz, Catherine; Poeze, Martijn; Preiser, Jean-Charles; Singer, Pierre; van Zanten, Arthur R.H.; De Waele, Jan; Wendon, Julia; ... (2017). Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines. Intensive care medicine, 43(3), pp. 380-398. Springer 10.1007/s00134-016-4665-0

Merz, Tobias; Pereira, Adriano J; Schürch, Roger; Schefold, Joerg C.; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2017). Mitochondrial function of immune cells in septic shock: A prospective observational cohort study. PLoS ONE, 12(6), e0178946. Public Library of Science 10.1371/journal.pone.0178946


Nobile, Leda; Taccone, Fabio S; Szakmany, Tamas; Sakr, Yasser; Jakob, Stephan; Pellis, Tommaso; Antonelli, Massimo; Leone, Marc; Wittebole, Xavier; Pickkers, Peter; Vincent, Jean-Louis (2016). The impact of extracerebral organ failure on outcome of patients after cardiac arrest: an observational study from the ICON database. Critical care, 20(1), p. 368. BioMed Central 10.1186/s13054-016-1528-6

Bhaskar, Monica; Jakob, Stephan; Djafarzadeh, Siamak (2 November 2016). Effect of cytomix and sedative drugs on mitochondrial electron transport chain of cultured primary human astrocytes (Unpublished). In: Day of Clinical Research 2016.

Pettilä, Ville Yrjö Olavi; Jakob, Stephan; Takala, Jukka (2016). The new sepsis/septic shock-3 definition is just not enough - more detailed research is needed. Acta anaesthesiologica Scandinavica, 60(10), pp. 1344-1346. Wiley-Blackwell 10.1111/aas.12777

Varis, Elina; Pettilä, Ville Yrjö Olavi; Poukkanen, Meri; Jakob, Stephan; Karlsson, Sari; Perner, Anders; Takala, Jukka; Wilkman, Erika (2016). Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the Finnaki Study. Shock, 47(5), pp. 574-581. Lippincott Williams & Wilkins 10.1097/SHK.0000000000000772

Martin-Loeches, Ignacio; Wunderink, Richard G; Nanchal, Rahul; Lefrant, Jean Yves; Kapadia, Farhad; Sakr, Yasser; Vincent, Jean-Louis; Jakob, Stephan (2016). Determinants of time to death in hospital in critically ill patients around the world. Intensive care medicine, 42(9), pp. 1454-1460. Springer 10.1007/s00134-016-4479-0

Eggmann, Sabrina; Verra, Martin L; Luder, Gere; Takala, Jukka; Jakob, Stephan (2016). Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial. Trials, 17, p. 403. BioMed Central 10.1186/s13063-016-1533-8

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Jeger, Victor; Takala, Jukka; Jakob, Stephan (2016). The Effects of Fentanyl on Hepatic Mitochondrial Function. Anesthesia and analgesia, 123(2), pp. 311-325. International Anesthesia Research Society 10.1213/ANE.0000000000001280

Pettilä, Ville Yrjö Olavi; Hjortrup, Peter Buhl; Jakob, Stephan; Wilkman, Erika; Perner, Anders; Takala, Jukka (2016). Control groups in recent septic shock trials: a systematic review. Intensive care medicine, 42(12), pp. 1912-1921. Springer 10.1007/s00134-016-4444-y

Berger, David; Werner Möller, Per; Weber, Alberto; Bloch, Andreas; Bloechlinger, Stefan; Hänggi, Matthias; Sondergaard, Soren; Jakob, Stephan; Magder, Sheldon; Takala, Jukka (2016). Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. American journal of physiology - heart and circulatory physiology, 311(3), H794-H806. American Physiological Society 10.1152/ajpheart.00931.2015

Takala, Jukka; Jakob, Stephan (2016). Oxygen transport in the critically ill. In: Webb, Andrew; Angus, Derek; Finfer, Simon; Gattinoni, Luciano; Singer, Mervyn (eds.) Oxford Textbook of Critical Care (pp. 636-639). Oxford University Press

Reintam Blaser, Annika; Jakob, Stephan; Starkopf, Joel (2016). Gastrointestinal failure in the ICU. Current opinion in critical care, 22(2), pp. 128-141. Lippincott Williams & Wilkins 10.1097/MCC.0000000000000286

Basciani, Reto Marco; Rindlisbacher, Antje; Begert, Esther; Brander, Luc; Jakob, Stephan; Etter, Reto; Carrel, Thierry; Eberle, Balthasar (2016). Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial. European journal of anaesthesiology, 33(6), pp. 417-424. Lippincott Williams & Wilkins 10.1097/EJA.0000000000000434

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Pettilä, Ville Yrjö Olavi; Merz, Tobias Michael; Wilkman, Erika; Perner, Anders; Karlsson, Sari; Lange, Theis; Hästbacka, Johanna; Hjortrup, Peter Buhl; Kuitunen, Anne; Jakob, Stephan; Takala, Jukka (2016). Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial. Trials, 17(384), p. 384. BioMed Central 10.1186/s13063-016-1515-x


Zubler, Frederic; Koenig, Christa; Steimer, Andreas; Jakob, Stephan; Schindler, Kaspar Anton; Gast, Heidemarie (2015). Prognostic and diagnostic value of EEG signal coupling measures in coma. Clinical neurophysiology, 127(8), pp. 2942-2952. Elsevier 10.1016/j.clinph.2015.08.022

Fung, Christian; Inglin, Fabienne; Murek, Michael Konrad; Balmer, Mathias; Abu-Isa, Janine; Z'Graggen, Werner Josef; Ozdoba, Christoph; Gralla, Jan; Jakob, Stephan; Takala, Jukka; Beck, Jürgen; Raabe, Andreas (2015). Reconsidering the logic of World Federation of Neurosurgical Societies grading in patients with severe subarachnoid hemorrhage. Journal of neurosurgery, 124(2), pp. 299-304. American Association of Neurological Surgeons 10.3171/2015.2.JNS14614

Merz, Tobias Michael; Pichler Hefti, Jacqueline Renée; Hefti, Urs; Huber, Andreas; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study. Redox report, 20(5), pp. 234-240. Maney Publishing 10.1179/1351000215Y.0000000007

Bloechlinger, Stefan; Berger, David; Bryner, Jürg; Roost, Eva; Jakob, Stephan; Dünser, Martin W; Takala, Jukka (2015). Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. Journal of cardiothoracic and vascular anesthesia, 29(4), pp. 860-867. Elsevier 10.1053/j.jvca.2015.01.010

Jakob, Stephan; Groeneveld, A B Johan; Teboul, Jean-Louis (2015). Venous-arterial CO2 to arterial-venous O2 difference ratio as a resuscitation target in shock states? Intensive care medicine, 41(5), pp. 936-938. Springer 10.1007/s00134-015-3778-1

Bänziger, B; Regueira, T; Vogt, R; Brandt, S; Vandevelde, M; Jakob, Stephan (2015). Neurohistological abnormalities during early porcine endotoxemia. Acta anaesthesiologica Scandinavica, 59(5), pp. 586-597. Wiley-Blackwell 10.1111/aas.12512

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC anesthesiology, 15(2), p. 2. BioMed Central 10.1186/1471-2253-15-2

Fung, Christian; Balmer, Mathias; Murek, Michael; Z'Graggen, Werner Josef; Abu-Isa, Janine; Ozdoba, Christoph; Hänggi, Matthias; Jakob, Stephan; Raabe, Andreas; Beck, Jürgen (2015). Impact of early-onset seizures on grading and outcome in patients with subarachnoid hemorrhage. Journal of neurosurgery, 122(2), pp. 408-413. American Association of Neurological Surgeons 10.3171/2014.10.JNS14163

Marbacher, Serge; Fathi, Ali Reza; Muroi, Carl; Coluccia, Daniel; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; Jakob, Stephan; Fandino, Javier (2015). The rabbit blood shunt subarachnoid haemorrhage model. Acta neurochirurgica - supplementa, 120, pp. 337-342. Springer 10.1007/978-3-319-04981-6_58

Ackermann, Karin; Brander, Lukas; Tuchscherer, Daniel; Schröder, Ralph; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2015). Esophageal versus surface recording of diaphragm compound muscle action potential. Muscle & nerve, 51(4), pp. 598-600. John Wiley & Sons 10.1002/mus.24577

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2015). Is lactate clearance impaired in septic shock? Critical care, 19(306), p. 306. BioMed Central 10.1186/s13054-015-1039-x

Corrêa, Thiago Domingos; Jakob, Stephan; Takala, Jukka (2015). Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? Critical care, 19(264), p. 264. BioMed Central 10.1186/s13054-015-0958-x

Turunen, Heidi; Jakob, Stephan; Ruokonen, Esko; Kaukonen, Kirsi-Maija; Sarapohja, Toni; Apajasalo, Marjo; Takala, Jukka (2015). Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation. Critical care, 19(67), p. 67. BioMed Central 10.1186/s13054-015-0787-y

Corrêa, Thiago D; Takala, Jukka; Jakob, Stephan (2015). Angiotensin II in septic shock. Critical care, 19(98), p. 98. BioMed Central 10.1186/s13054-015-0802-3

Jeger, Victor; Brandt, Sebastian; Porta, Francesca; Jakob, Stephan; Takala, Jukka; Djafarzadeh, Siamak (2015). Dose response of endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed research international, 2015, p. 353074. Hindawi Publishing Corporation 10.1155/2015/353074


Marbacher, Serge; Nevzati, Edin; Croci, Davide; Erhardt, Salome; Muroi, Carl; Jakob, Stephan; Fandino, Javier (2014). The Rabbit Shunt Model of Subarachnoid Haemorrhage. Translational stroke research, 5(6), pp. 669-680. Springer 10.1007/s12975-014-0369-3

Marbacher, Serge; Neuschmelting, Volker; Andereggen, Lukas; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2014). Early brain injury linearly correlates with reduction in cerebral perfusion pressure during the hyperacute phase of subarachnoid hemorrhage. Intensive care medicine experimental, 2(1), p. 30. Springer 10.1186/s40635-014-0030-1

Andereggen, Lukas; Neuschmelting, Volker; von Gunten, Michael; Widmer, Hans Rudolf; Takala, Jukka; Jakob, Stephan; Fandino, Javier; Marbacher, Serge (2014). The Rabbit Blood-shunt Model for the Study of Acute and Late Sequelae of Subarachnoid Hemorrhage: Technical Aspects. Journal of visualized experiments(92), e52132. MYJoVE Corporation 10.3791/52132

Hänggi, Matthias; Jakob, Stephan; Takala, Jukka (2014). Sedation level and prevalence of delirium: response to Brummel and Ely. Intensive care medicine, 40(1), p. 136. Springer 10.1007/s00134-013-3092-8

Pereira, A. J.; Jeger, V.; Fahrner, R.; Djafarzadeh, Siamak; Lensch, Michael; Takala, Jukka; Jakob, Stephan (2014). Interference of angiotensin II and enalapril with hepatic blood flow regulation. American journal of physiology - gastrointestinal and liver physiology, 307(6), G655-G663. American Physiological Society 10.1152/ajpgi.00150.2014

Corrêa, Thiago D.; Jeger, Victor; Pereira, Adriano José; Takala, Jukka; Djafarzadeh, Siamak; Jakob, Stephan (2014). Angiotensin II in Septic Shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Critical care medicine, 42(8), e550-e559. Lippincott Williams & Wilkins 10.1097/CCM.0000000000000397

Ackermann, Karin; Bostock, Hugh; Brander, Lukas; Schröder, Ralph; Djafarzadeh, Siamak; Tuchscherer, Daniel; Jakob, Stephan; Takala, Jukka; Z'Graggen, Werner Josef (2014). Early changes of muscle membrane properties in porcine faecal peritonitis. Critical care, 18(4), p. 484. BioMed Central 10.1186/s13054-014-0484-2

Jakob, Stephan; Ruokonen, E.; Takala, Jukka (2014). Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. British journal of anaesthesia, 112(3), pp. 581-582. Oxford University Press 10.1093/bja/aeu032


Gorrasi, José; Eleftheriadis, Anestis; Takala, Jukka; Brandt, Sebastian; Djafarzadeh, Siamak; Brügger, Lukas; Bracht, Hendrik; Jakob, Stephan (2013). Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade. BioMed research international, 2013, pp. 1-8. Hindawi Publishing Corporation 10.1155/2013/251084

Astin, Ronan; Bentham, Robert; Djafarzadeh, Siamak; Horscroft, James A.; Kuc, Rhoda E.; Leung, Po Sing; Skipworth, James R. A.; Vicencio, Jose M.; Davenport, Anthony P.; Murray, Andrew J.; Takala, Jukka; Jakob, Stephan; Montgomery, Hugh; Szabadkai, Gyorgy (2013). No evidence for a local renin-angiotensin system in liver mitochondria. Scientific Reports, 3(1), p. 2467. Nature Publishing Group 10.1038/srep02467

Hänggi, Matthias; Blum, Sina; Brechbuehl, Ruth; Brunello, Anna; Jakob, Stephan; Takala, Jukka (2013). Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC. Intensive care medicine, 39(12), pp. 2171-2179. Springer 10.1007/s00134-013-3034-5

Corrêa, Thiago Domingos; Takala, Jukka; Jakob, Stephan (2013). Target blood pressure in sepsis: between a rock and a hard place. Critical care, 17(3), p. 433. BioMed Central 10.1186/cc12692

Jeger, Victor; Djafarzadeh, Siamak; Jakob, Stephan; Takala, Jukka (2013). Mitochondrial function in sepsis. European journal of clinical investigation, 43(5), pp. 532-542. Wiley-Blackwell 10.1111/eci.12069

Corrêa, Thiago Domingos; Vuda, Madhusudanarao; Takala, Jukka; Djafarzadeh, Siamak; Silva, Eliézer; Jakob, Stephan (2013). Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function. Critical care, 17(1), R21. BioMed Central 10.1186/cc12495

Lehmann, Laura; Bendel, Stepani; Uehlinger, Dominik E; Takala, Jukka; Schafer, Margaret; Reinert, Michael; Jakob, Stephan M (2013). Randomized, Double-Blind Trial of the Effect of Fluid Composition on Electrolyte, Acid-Base, and Fluid Homeostasis in Patients Early After Subarachnoid Hemorrhage. Neurocritical care, 18(1), pp. 5-12. New York, N.Y.: Springer 10.1007/s12028-012-9764-3

Torgersen, Christian-Erik; Meichtry, Jurka; Schmittinger, Christian A; Blöchlinger, Stefan; Jakob, Stephan M; Takala, Jukka; Dünser, Martin Wolfgang (2013). Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. Resuscitation, 84(6), pp. 798-804. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2012.10.012


Vuda, Madhusudanarao; Brander, Lukas; Schröeder, Ralph; Jakob, Stephan M; Takala, Jukka; Djafarzadeh, Siamak (2012). Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs. Innate immunity, 18(2), pp. 217-30. Los Angeles, Calif.: Sage Publications 10.1177/1753425911398279

Fung, Christian; Z'graggen, Werner J; Beck, Jürgen; Gralla, Jan; Jakob, Stephan M; Schucht, Philippe; Raabe, Andreas (2012). Traumatic subarachnoid hemorrhage, basal ganglia hematoma and ischemic stroke caused by a torn lenticulostriate artery. Acta neurochirurgica, 154(1), pp. 59-62. Wien: Springer 10.1007/s00701-011-1162-7

Jakob, Stephan M; Bracht, Hendrik; Porta, Francesca; Balsiger, Bruno M; Brander, Lukas; Knuesel, Rafael; Feng, Hong-Qiang; Kolarova, Anna; Ma, Yingmin; Takala, Jukka (2012). Effects of cardiac preload reduction and dobutamine on hepatosplanchnic blood flow regulation in porcine endotoxemia. American journal of physiology - gastrointestinal and liver physiology, 303(2), G247-55. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00433.2011

Chiusa, Manuel; Hool, Sara-Lynn; Truetsch, Petra; Djafarzadeh, Siamak; Jakob, Stephan M; Seifriz, Franziska; Scherer, Stefan J; Suter, Thomas M; Zuppinger, Christian; Zbinden, Stephan (2012). Cancer therapy modulates VEGF signaling and viability in adult rat cardiac microvascular endothelial cells and cardiomyocytes. Journal of molecular and cellular cardiology, 52(5), pp. 1164-75. Oxford: Elsevier 10.1016/j.yjmcc.2012.01.022

Jakob, Stephan M; Ruokonen, Esko; Grounds, R Michael; Sarapohja, Toni; Garratt, Chris; Pocock, Stuart J; Bratty, J Raymond; Takala, Jukka; Dexmedetomidine for Long-Term Sedation, Investigators (2012). Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. JAMA - the journal of the American Medical Association, 307(11), pp. 1151-60. Chicago, Ill.: American Medical Association 10.1001/jama.2012.304

Jeitziner, M-M; Schwendimann, R; Hamers, J P H; Rohrer, O; Hantikainen, V; Jakob, S M (2012). Assessment of pain in sedated and mechanically ventilated patients: an observational study. Acta anaesthesiologica Scandinavica, 56(5), pp. 645-54. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02660.x

Reintam Blaser, Annika; Malbrain, Manu L N G; Starkopf, Joel; Fruhwald, Sonja; Jakob, Stephan M; De Waele, Jan; Braun, Jan-Peter; Poeze, Martijn; Spies, Claudia (2012). Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems. Intensive care medicine, 38(3), pp. 384-94. Berlin: Springer 10.1007/s00134-011-2459-y

Brügger, Lukas E; Beldi, Guido; Stalder, Michael; Porta, Francesca; Candinas, Daniel; Takala, Jukka; Jakob, Stephan M (2012). Postoperative splanchnic blood flow redistribution in response to fluid challenges in the presence and absence of endotoxemia in a porcine model. Shock, 37(1), pp. 116-21. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e31823917eb

Corrêa, Thiago D; Vuda, Madhusudanarao; Blaser, Annika Reintam; Takala, Jukka; Djafarzadeh, Siamak; Dünser, Martin W; Silva, Eliézer; Lensch, Michael; Wilkens, Ludwig; Jakob, Stephan M (2012). Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis. Critical care medicine, 40(10), pp. 2841-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e31825b916b

Marbacher, Serge; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; von Gunten, Michael; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2012). A new rabbit model for the study of early brain injury after subarachnoid hemorrhage. Journal of neuroscience methods, 208(2), pp. 138-45. Amsterdam: Elsevier 10.1016/j.jneumeth.2012.05.010

Regueira, T; Djafarzadeh, S; Brandt, S; Gorrasi, J; Borotto, E; Porta, F; Takala, J; Bracht, H; Shaw, S; Lepper, P M; Jakob, S M (2012). Oxygen transport and mitochondrial function in porcine septic shock, cardiogenic shock, and hypoxaemia. Acta anaesthesiologica Scandinavica, 56(7), pp. 846-59. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02706.x

Ganter, C C; Hochuli, R; Bossard, M; Etter, Reto; Takala, J; Uehlinger, D E; Jakob, S M (2012). Forced fluid removal in critically ill patients with acute kidney injury. Acta anaesthesiologica Scandinavica, 56(9), pp. 1183-90. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2012.02734.x

Shafighi, Maziar; Olariu, Radu; Brun, Claudio; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Hunger, Robert E; Banic, Andrej; Constantinescu, Mihai A (2012). The role of androgens on hypoxia-inducible factor (HIF)-1α-induced angiogenesis and on the survival of ischemically challenged skin flaps in a rat model. Microsurgery, 32(6), pp. 475-81. New York, N.Y.: Wiley-Liss 10.1002/micr.21996

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M (2012). Effect of remifentanil on mitochondrial oxygen consumption of cultured human hepatocytes. PLoS ONE, 7(9), e45195. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0045195


Banz, Vanessa M; Jakob, Stephan M; Inderbitzin, Daniel (2011). Improving Outcome After Major Surgery: Pathophysiological Considerations. Anesthesia and analgesia, 112(5), pp. 1147-55. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ANE.0b013e3181ed114e

Djafarzadeh, Siamak; Vuda, Madhusudanarao; Takala, Jukka; Ochs, Matthias; Jakob, Stephan M (2011). Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. Mitochondrion, 11(1), pp. 83-8. Amsterdam: Elsevier 10.1016/j.mito.2010.07.010

Haenggi, Matthias; Barthelmes, Daniel; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M (2011). Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest. Resuscitation, 82(4), pp. 423-6. Shannon: Elsevier Science Ireland 10.1016/j.resuscitation.2010.12.015

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan; Fandino, Javier (2011). Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. Acta neurochirurgica - supplementa, 110(Pt 1), pp. 163-5. Wien: Springer 10.1007/978-3-7091-0353-1_28

Torgersen, Christian; Dünser, Martin W; Schmittinger, Christian A; Pettilä, Ville; Ruokonen, Esko; Wenzel, Volker; Jakob, Stephan M; Takala, Jukka (2011). Current approach to the haemodynamic management of septic shock patients in European intensive care units: a cross-sectional, self-reported questionnaire-based survey. European journal of anaesthesiology, 28(4), pp. 284-90. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/EJA.0b013e3283405062

Fathi, Ali Reza; Marbacher, Serge; Graupner, Thilo; Wehrli, Felix; Jakob, Stephan M; Schroth, Gerhard; Fandino, Javier (2011). Continuous intrathecal glyceryl trinitrate prevents delayed cerebral vasospasm in the single-SAH rabbit model in vivo. Acta neurochirurgica, 153(8), 1669-75; discussion 1675. Wien: Springer 10.1007/s00701-011-1049-7

Takala, Jukka; Ruokonen, Esko; Tenhunen, Jyrki J; Parviainen, Ilkka; Jakob, Stephan M (2011). Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial. Critical care, 15(3), R148. London: BioMed Central 10.1186/cc10273

Kessler, Ulf; Grau, Tamar; Gronchi, Fabrizio; Berger, Steffen; Brandt, Sebastian; Bracht, Hendrik; Marcucci, Carlo; Zachariou, Zacharias; Jakob, Stephan M (2011). Comparison of porcine and human coagulation by thrombelastometry. Thrombosis research, 128(5), pp. 477-82. Amsterdam: Elsevier 10.1016/j.thromres.2011.03.013

Shafighi, Maziar; Olariu, Radu; Fathi, Ali R; Djafarzadeh, Siamak; Jakob, Stephan M; Banic, Andrej; Constantinescu, Mihai A (2011). Dimethyloxalylglycine stabilizes HIF-1α in cultured human endothelial cells and increases random-pattern skin flap survival in vivo. PLASTIC AND RECONSTRUCTIVE SURGERY, 128(2), pp. 415-22. 10.1097/PRS.0b013e31821e6e69

Hofmann, Eveline; Marbach, Serge; Jakob, Stephan M; Takala, Jukka; Remonda, Luca; Fandino, Javier (2011). Incidence of vasospasm, outcome, and quality of life after endovascular and surgical treatment of ruptured intracranial aneurysms: results of a single-center prospective study in Switzerland. ISRN vascular medicine, 2011 New York, N.Y.: International Scholarly Research Network ISRN


Brunello, Anna-Giulia; Haenggi, Matthias; Wigger, Oliver; Porta, Francesca; Takala, Jukka; Jakob, Stephan M (2010). Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure. Intensive care medicine, 36(1), pp. 66-74. Berlin: Springer 10.1007/s00134-009-1645-7

Spirig, Rolf; Djafarzadeh, Siamak; Regueira, Tomas; Shaw, Sidney G; von Garnier, Christophe; Takala, Jukka; Jakob, Stephan M; Rieben, Robert; Lepper, Philipp M (2010). Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions. PLoS ONE, 5(6), e0010983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0010983

Jakob, Stephan M; Stanga, Zeno (2010). Perioperative metabolic changes in patients undergoing cardiac surgery. Nutrition, 26(4), pp. 349-53. New York, N.Y.: Elsevier 10.1016/j.nut.2009.07.014

Daudel, Fritz; Gorrasi, José; Bracht, Hendrik; Brandt, Sebastian; Krejci, Vladimir; Jakob, Stephan M; Takala, Jukka; Rothen, Hans Ulrich (2010). Effects of lung recruitment maneuvers on splanchnic organ perfusion during endotoxin-induced pulmonary arterial hypertension. Shock, 34(5), pp. 488-94. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181e03bfb

Brügger, Lukas E; Beldi, Guido; Beck, Mario; Porta, Francesca; Bracht, Hendrik; Candinas, Daniel; Takala, Jukka; Jakob, Stephan M (2010). Splanchnic vasoregulation after major abdominal surgery in pigs. World journal of surgery, 34(9), pp. 2057-63. New York, N.Y.: Springer

Barthelmes, D; Jakob, S M; Laitinen, S; Rahikainen, S; Ahonen, H; Takala, J (2010). Effect of site of lactate infusion on regional lactate exchange in pigs. British journal of anaesthesia, 105(5), pp. 627-34. Oxford: Oxford University Press 10.1093/bja/aeq214

Wyler von Ballmoos, Moritz; Takala, Jukka; Roeck, Margareta; Porta, Francesca; Tueller, David; Ganter, Christoph C; Schröder, Ralph; Bracht, Hendrik; Baenziger, Bertram; Jakob, Stephan M (2010). Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study. Critical care, 14(3), R111. London: BioMed Central 10.1186/cc9060

Passath, Christina; Takala, Jukka; Tuchscherer, Daniel; Jakob, Stephan M; Sinderby, Christer; Brander, Lukas (2010). Physiologic response to changing positive end-expiratory pressure during neurally adjusted ventilatory assist in sedated, critically ill adults. Chest, 138(3), pp. 578-87. Northbrook, Ill.: American College of Chest Physicians 10.1378/chest.10-0286

Dahlqvist, Mats B; Andres, Robert H; Raabe, Andreas; Jakob, Stephan M; Takala, Jukka; Dünser, Martin W (2010). Brain herniation in a patient with apparently normal intracranial pressure: a case report. Journal of medical case reports, 4, p. 297. London: BioMed Central

Daudel, Fritz; Tüller, David; Krähenbühl, Stefanie; Jakob, Stephan M; Takala, Jukka (2010). Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study. Critical care, 14(3), R122. London: BioMed Central 10.1186/cc9080

Torgersen, C; Schmittinger, C A; Takala, J; Jakob, S M; Dünser, M W (2010). The association between early hemodynamic variables and outcome in normothermic comatose patients following cardiac arrest. Acta anaesthesiologica Scandinavica, 54(8), pp. 1027-35. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2010.02273.x

Marbacher, Serge; Sherif, Camillo; Neuschmelting, Volker; Schläppi, Janine-Ai; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2010). Extra-intracranial blood shunt mimicking aneurysm rupture: intracranial-pressure-controlled rabbit subarachnoid hemorrhage model. Journal of neuroscience methods, 191(2), pp. 227-33. Amsterdam: Elsevier 10.1016/j.jneumeth.2010.07.004

Jakob, (2010). Does hypercapnic acidosis preserve mucosal oxygenation during hemorrhage? Shock, 34(6), pp. 649-50. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181e86ec8

Jakob, Stephan M; Knuesel, Rafael; Tenhunen, Jyrki J; Pradl, Richard; Takala, Jukka (2010). Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures. BMC gastroenterology, 10, p. 70. London: BioMed Central 10.1186/1471-230X-10-70

Jeger, Victor; Jakob, Stephan M; Fontana, Stefano; Wolf, Martin; Zimmermann, Heinz; Exadaktylos, Aristomenis K (2010). 500 ml of blood loss does not decrease non-invasive tissue oxygen saturation (StO2) as measured by near infrared spectroscopy - A hypothesis generating pilot study in healthy adult women. Journal of trauma management & outcomes, 4, p. 5. London: BioMed Central 10.1186/1752-2897-4-5

Jakob, Stephan (2010). The effects of mechanical ventilation on hepato-splanchnic perfusion. Current opinion in critical care, 16(2), pp. 165-168. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MCC.0b013e3283374b1c


Ruokonen, Esko; Parviainen, Ilkka; Jakob, Stephan M; Nunes, Silvia; Kaukonen, Maija; Shepherd, Stephen T; Sarapohja, Toni; Bratty, J Raymond; Takala, Jukka (2009). Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation. Intensive care medicine, 35(2), pp. 282-90. Berlin: Springer 10.1007/s00134-008-1296-0

Ganter, Christoph; Buser, Christof; Haenggi, Matthias; Mattes, Hanswilly; Takala, Jukka; Jakob, Stephan (2009). Inverse thermodilution with conventional pulmonary artery catheters for the assessment of cerebral, hepatic, renal, and femoral blood flow. Shock, 32(2), pp. 194-200. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e318194c73a

Neuschmelting, Volker; Fathi, Ali-Reza; Hidalgo Staub, Eveline Teresa; Marbacher, Serge; Schroth, Gerhard; Takala, Jukka; Jakob, Stephan M; Fandino, Javier (2009). Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(5), pp. 487-93. Wien: Springer 10.1007/s00701-009-0287-4

von Gunten, Stephan; Jakob, Stephan M; Geering, Barbara; Takala, Jukka; Simon, Hans-Uwe (2009). Different patterns of Siglec-9-mediated neutrophil death responses in septic shock. Shock, 32(4), pp. 386-92. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e3181a1bc98

Haenggi, Matthias; Ypparila-Wolters, Heidi; Buerki, Sarah; Schlauri, Rebekka; Korhonen, Ilkka; Takala, Jukka; Jakob, Stephan M (2009). Auditory event-related potentials, bispectral index, and entropy for the discrimination of different levels of sedation in intensive care unit patients. Anesthesia and analgesia, 109(3), pp. 807-16. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ane.0b013e3181acc85d

Neuschmelting, Volker; Marbacher, Serge; Fathi, Ali-Reza; Jakob, Stephan M; Fandino, Javier (2009). Elevated level of endothelin-1 in cerebrospinal fluid and lack of nitric oxide in basilar arterial plasma associated with cerebral vasospasm after subarachnoid haemorrhage in rabbits. Acta neurochirurgica, 151(7), 795-801; discussion 801-2. Wien: Springer 10.1007/s00701-009-0350-1

Barthelmes, Daniel; Parviainen, Ilkka; Vainio, Pauli; Vanninen, Ritva; Takala, Jukka; Ikonen, Aki; Tueller, David; Jakob, Stephan M (2009). Assessment of splanchnic blood flow using magnetic resonance imaging. European journal of gastroenterology & hepatology, 21(6), pp. 693-700. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/MEG.0b013e32831a86e0

Brander, Lukas; Haltmeier, Tobias; Suter, Anna; Studer, Peter; Inderbitzin, Daniel; Candinas, Daniel; Vogt, Andreas; Henzen, Christoph; Takala, Jukka; Jakob, Stephan M (2009). Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. Surgery, 146(1), pp. 88-99. New York, N.Y.: Elsevier 10.1016/j.surg.2009.01.018

Regueira, Tomas; Lepper, Philipp M; Brandt, Sebastian; Ochs, Matthias; Vuda, Madhusudanarao; Takala, Jukka; Jakob, Stephan M; Djafarzadeh, Siamak (2009). Hypoxia inducible factor-1 alpha induction by tumour necrosis factor-alpha, but not by toll-like receptor agonists, modulates cellular respiration in cultured human hepatocytes. Liver international, 29(10), pp. 1582-92. Oxford: Blackwell Munksgaard 10.1111/j.1478-3231.2009.02109.x

Daudel, Fritz; Kessler, Ulf; Folly, Hélène; Lienert, Jasmin S; Takala, Jukka; Jakob, Stephan M (2009). Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study. Critical care, 13(2), R42. London: BioMed Central 10.1186/cc7765

Dünser, Martin W; Takala, Jukka; Ulmer, Hanno; Mayr, Viktoria D; Luckner, Günter; Jochberger, Stefan; Daudel, Fritz; Lepper, Philipp; Hasibeder, Walter R; Jakob, Stephan M (2009). Arterial blood pressure during early sepsis and outcome. Intensive care medicine, 35(7), pp. 1225-33. Berlin: Springer 10.1007/s00134-009-1427-2

Dünser, Martin W; Ruokonen, Esko; Pettilä, Ville; Ulmer, Hanno; Torgersen, Christian; Schmittinger, Christian A; Jakob, Stephan; Takala, Jukka (2009). Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial. Critical care, 13(6), R181. London: BioMed Central 10.1186/cc8167

Dünser, Martin W; Bataar, Otgon; Tsenddorj, Ganbat; Lundeg, Ganbold; Jochberger, Stefan; Jakob, Stephan (2009). Intensive care medicine in Mongolia's 3 largest cities: outlining the needs. Journal of critical care, 24(3), 469.e1-6. New York, N.Y.: Elsevier 10.1016/j.jcrc.2008.06.014

Haenggi, Matthias; Ypparila-Wolters, Heidi; Hauser, Kathrin; Caviezel, Claudio; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2009). Intra- and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. Critical care, 13(1), R20. London: BioMed Central 10.1186/cc7723

Torgersen, Christian; Schmittinger, Christian A; Wagner, Sarah; Ulmer, Hanno; Takala, Jukka; Jakob, Stephan M; Dünser, Martin W (2009). Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study. Critical care, 13(5), R157. London: BioMed Central 10.1186/cc8114

Farese, Stefan; Jakob, Stephan M; Kalicki, Robert; Frey, Felix J; Uehlinger, Dominik E (2009). Treatment of acute renal failure in the intensive care unit: lower costs by intermittent dialysis than continuous venovenous hemodiafiltration. Artificial organs, 33(8), pp. 634-40. Malden, Mass.: Wiley-Blackwell 10.1111/j.1525-1594.2009.00794.x

Jakob, Stephan (2009). Septic shock resuscitation: what goals and how to achieve them? Critical care, 13(3), p. 147. London: BioMed Central 10.1186/cc7870

Arnberger, Michael; Vogt, Andreas; Studer, Peter; Inderbitzin, Daniel; Pulver, Carole; Röhrig, Bernd; Jakob, Stephan M; Greif, Robert (2009). Evaluation of physical and mental recovery status after elective liver resection. European journal of anaesthesiology, 26(7), pp. 559-65. Philadelphia, Pa.: Lippincott Williams & Wilkins 10.1097/EJA.0b013e328328f552

Jakob, Stephan M; Takala, Jukka (2009). Physical and occupational therapy during sedation stops. Lancet, 373(9678), pp. 1824-6. London: Elsevier 10.1016/S0140-6736(09)60866-7

Takala, Jukka; Jakob, Stephan M (2009). Shedding light on microcirculation? Intensive care medicine, 35(3), pp. 394-6. Berlin: Springer 10.1007/s00134-008-1386-z

Jakob, Stephan M; Parviainen, Ilkka; Ruokonen, Esko; Hinder, Raffael; Uusaro, Ari; Takala, Jukka (2009). Increased splanchnic oxygen extraction because of routine nursing procedures. Critical care medicine, 37(2), pp. 483-9. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/CCM.0b013e3181958821

Porta, Francesca; Bracht, Hendrik; Weikert, Christian; Beck, Mario; Takala, Jukka; Brandt, Sebastian; Hiltebrand, Luzius B; Jakob, Stephan M (2009). Effects of endotoxin and catecholamines on hepatic mitochondrial respiration. Inflammation, 32(5), pp. 315-21. New York, N.Y.: Springer 10.1007/s10753-009-9138-y


Nyberg, A; Jakob, S M; Seeman-Lodding, H; Porta, F; Bracht, H; Bischofberger, H; Jern, C; Takala, J; Aneman, A (2008). Time- and dose-related regional fluxes of tissue-type plasminogen activator in anesthetized endotoxemic pigs. Acta anaesthesiologica Scandinavica, 52(1), pp. 57-64. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2007.01481.x

Bracht, Hendrik; Krejci, Vladimir; Hiltebrand, Luzius; Brandt, Sebastian; Sigurdsson, Gisli; Ali, Syed Z; Takala, Jukka; Jakob, Stephan M (2008). Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion. Intensive care medicine, 34(10), pp. 1883-90. Berlin: Springer 10.1007/s00134-008-1130-8

Taniguchi, Yoshie; Bracht, Hendrik; Porta, Francesca; Krejci, Vladimir; Ali, Sayed Z; Beck, Mario; Mettler, Daniel; Takala, Jukka; Jakob, Stephan M (2008). Thermodilution and esophageal Doppler ultrasound in the assessment of blood flow changes induced by endotoxin and dobutamine. Journal of trauma - injury, infection, and critical care, 65(1), pp. 175-82. Baltimore, Md.: Lippincott, Williams, & Wilkins 10.1097/TA.0b013e31815eb0ff

Ali, Syed Z; Bracht, Hendrik; Krejci, Vladimir; Beck, Mario; Stalder, Michael; Hiltebrand, Luzius; Takala, Jukka; Brandt, Sebastian; Jakob, Stephan M (2008). The immediate and sustained effects of volume challenge on regional blood flows in pigs. Anesthesia and analgesia, 106(2), 595-600, table of contents. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/ane.0b013e31816064d2

Regueira, Tomas; Bänziger, Bertram; Djafarzadeh, Siamak; Brandt, Sebastian; Gorrasi, Jose; Takala, Jukka; Lepper, Philipp M; Jakob, Stephan M (2008). Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration. Critical care, 12(4), R88. London: BioMed Central 10.1186/cc6956

Marbacher, Serge; Neuschmelting, Volker; Graupner, Thilo; Jakob, Stephan M; Fandino, Javier (2008). Prevention of delayed cerebral vasospasm by continuous intrathecal infusion of glyceroltrinitrate and nimodipine in the rabbit model in vivo. Intensive care medicine, 34(5), pp. 932-8. Berlin: Springer 10.1007/s00134-008-0995-x

Jakob, Stephan (2008). It makes a difference! Wiener klinische Wochenschrift, 120(19-20), pp. 581-2. Wien: Springer 10.1007/s00508-008-1082-6

Hänggi, Matthias; Ypparila-Wolters, Heidi; Bieri, Christine; Steiner, Carola; Takala, Jukka; Korhonen, Ilkka; Jakob, Stephan M (2008). Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study. Critical care, 12(5), R119. London: BioMed Central 10.1186/cc7015

Takala, Jukka; Dellinger, R Philip; Koskinen, Kati; St Andre, Arthur; Read, Martyn; Levy, Mitchell; Jakob, Stephan M; Mello, Patricia Veiga C; Friolet, Raymond; Ruokonen, Esko (2008). Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study. Intensive care medicine, 34(8), pp. 1401-10. Berlin: Springer 10.1007/s00134-008-1084-x

Lötscher, S; Wermelinger, VR; Jakob, SM; Merz, TM (2008). Hämophagozytose-Syndrom mit massivem capillary leak. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, -8(46), pp. 898-900. Basel: EMH Editores Medicorum Helveticorum

Regueira, Tomas Emilio; Jakob, Stephan; Djafarzadeh, Siamak (2008). Regulation of mitochondrial function by hypoxia and inflammation in sepsis: A putative role for hypoxia inducible factor. In: Vincent, Jean-Louis (ed.) Yearbook of Intensive Care and Emergency Medicine 2008 (pp. 385-394). Heidelberg: Springer 10.1007/978-3-540-77290-3_36


Plock, Jan; Frese, Steffen; Keogh, Adrian; Bisch-Knaden, Sonja; Ayuni, Erick; Corazza, Nadia; Weikert, Christian; Jakob, Stephan; Erni, Dominique; Dufour, Jean-François; Brunner, Thomas; Candinas, Daniel; Stroka, Deborah (2007). Activation of non-ischemic, hypoxia-inducible signalling pathways up-regulate cytoprotective genes in the murine liver. Journal of hepatology, 47(4), pp. 538-45. Amsterdam: Elsevier 10.1016/j.jhep.2007.04.016

Krejci, Vladimir; Hiltebrand, Luzius B; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care, 11(6), R129. London: BioMed Central 10.1186/cc6197

Jakob, Stephan M; Parviainen, Ilkka; Ruokonen, Esko; Kogan, Alexander; Takala, Jukka (2007). TONOMETRY REVISITED: PERFUSION-RELATED, METABOLIC, AND RESPIRATORY COMPONENTS OF GASTRIC MUCOSAL ACIDOSIS IN ACUTE CARDIORESPIRATORY FAILURE. Shock, 29(5), pp. 543-548. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/SHK.0b013e31815d0c10

Jakob, Stephan M; Lubszky, Szabina; Friolet, Raymond; Rothen, Hans Ulrich; Kolarova, Anna; Takala, Jukka (2007). Sedation and weaning from mechanical ventilation: effects of process optimization outside a clinical trial. Journal of critical care, 22(3), pp. 219-28. New York, N.Y.: Elsevier 10.1016/j.jcrc.2007.01.001

Knuesel, Rafael; Takala, Jukka; Brander, Lukas; Haenggi, Matthias; Bracht, Hendrik; Porta, Francesca; Jakob, Stephan M (2007). Intraperitoneal microdialysis: critique of an editorial. Critical care medicine, 35(7), 1802; discussion 1802. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000269345.99949.3D

Hiltebrand, Luzius B; Krejci, Vladimir; Jakob, Stephan M; Takala, Jukka; Sigurdsson, Gisli H (2007). Effects of vasopressin on microcirculatory blood flow in the gastrointestinal tract in anesthetized pigs in septic shock. Anesthesiology, 106(6), pp. 1156-67. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.anes.0000267599.02140.86

Contaldo, C; Harder, Y; Plock, J; Banic, A; Jakob, S M; Erni, D (2007). The influence of local and systemic preconditioning on oxygenation, metabolism and survival in critically ischaemic skin flaps in pigs. Journal of plastic, reconstructive & aesthetic surgery, 60(11), pp. 1182-92. Amsterdam: Elsevier 10.1016/j.bjps.2007.02.011

Bracht, Hendrik; Hänggi, Matthias; Jeker, Barbara; Wegmüller, Ninja; Porta, Francesca; Tüller, David; Takala, Jukka; Jakob, Stephan M (2007). Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study. Critical care, 11(1), R2. London: BioMed Central 10.1186/cc5144

Fandino, J; Fathi, A R; Graupner, T; Jakob, S; Landolt, H (2007). [Perspectives in the treatment of subarachnoid-hemorrhage-induced cerebral vasospasm]. Neurocirugía, 18(1), pp. 16-27. Madrid: Siglo


Porta, Francesca; Takala, Jukka; Weikert, Christian; Bracht, Hendrik; Kolarova, Anna; Lauterburg, Bernhard H; Borotto, Erika; Jakob, Stephan M (2006). Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function. Critical care, 10(4), R118. London: BioMed Central 10.1186/cc5013

Fux, Christoph A; Bianchetti, Mario G; Jakob, Stephan M; Remonda, Luca (2006). Reversible encephalopathy complicating post-streptococcal glomerulonephritis. Pediatric infectious disease journal, 25(1), pp. 85-7. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.imf.0000195614.66987.2f

Krejci, Vladimir; Hiltebrand, Luzius; Büchi, Conradin; Ali, Syed Z; Contaldo, Claudio; Takala, Jukka; Sigurdsson, Gisli H; Jakob, Stephan M (2006). Decreasing gut wall glucose as an early marker of impaired intestinal perfusion. Critical care medicine, 34(9), pp. 2406-14. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000233855.34344.29

Luginbühl, M; Rüfenacht, M; Korhonen, I; Gils, M; Jakob, S; Petersen-Felix, S (2006). Stimulation induced variability of pulse plethysmography does not discriminate responsiveness to intubation. British journal of anaesthesia, 96(3), pp. 323-9. Oxford: Oxford University Press 10.1093/bja/aeo315

Knuesel, Rafael; Takala, Jukka; Brander, Lukas; Haenggi, Matthias; Bracht, Hendrik; Porta, Francesca; Jakob, Stephan M (2006). Membrane microdialysis: Evaluation of a new method to assess splanchnic tissue metabolism. Critical care medicine, 34(10), pp. 2638-45. Baltimore, Md.: Lippincott Williams & Wilkins 10.1097/01.CCM.0000239430.73826.23

Brander, Lukas; Jakob, Stephan M; Knuesel, Rafael; Savolainen, Hannu; Widmer, Matthias K; Schmidli, Juerg; Takala, Jukka (2006). Effects of low abdominal blood flow and dobutamine on blood flow distribution and on the hepatic arterial buffer response in anaesthetized pigs. Shock, 25(4), pp. 402-13. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/01.0000217813.50104.5d

Ganter, CG; Jakob, SM; Takala, J (2006). Pulmonary capillary pressure. A review. Minerva anestesiologica, 72(1-2), pp. 21-36. Torino: Minerva Medica

Haenggi, Matthias; Ypparila, Heidi; Hauser, Kathrin; Caviezel, Claudio; Korhonen, Ilkka; Takala, Jukka; Jakob, Stephan M (2006). The effects of dexmedetomidine/remifentanil and midazolam/remifentanil on auditory-evoked potentials and electroencephalogram at light-to-moderate sedation levels in healthy subjects. Anesthesia and analgesia, 103(5), pp. 1163-9. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1213/01.ane.0000237394.21087.85

Porta, Francesca; Takala, Jukka; Weikert, Christian; Kaufmann, Priska; Krahenbuhl, Stephan; Jakob, Stephan M (2006). Effect of endotoxin, dobutamine and dopamine on muscle mitochondrial respiration in vitro. Journal of endotoxin research, 12(6), pp. 358-66. London: Sage 10.1179/096805106X153952

Collaborative Study Group on Perioperative ScvO2 Monitoring (KIM, H; Haenggi, M; Jakob, SM; Loher, S; Raeber, C; Takala, J) (2006). Multicentre study on peri- and postoperative central venous oxygen saturation in high-risk surgical patients. Critical care, 10(6), R158. London: BioMed Central 10.1186/cc5094

Parviainen, I; Jakob, SM; Suistomaa, M; Takala, J; The, Scandinavian Society of Anaesthesiology; Intensive, Care Medicine (SSAI) (2006). Practical sources of error in measuring pulmonary artery occlusion pressure: a study in participants of a special intensivist training program of The Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI). Acta anaesthesiologica Scandinavica, 50(5), pp. 600-3. Oxford: Wiley-Blackwell 10.1111/j.1399-6576.2006.01008.x

Braun, Jan-Peter; Jakob, Stephan M; Volk, Thomas; Doepfmer, Ulrich R; Moshirzadeh, Maryam; Stegmann, Shirin; Dohmen, Pascal M; Spies, Claudia (2006). Arterio-venous gradients of free energy change for assessment of systemic and splanchnic perfusion in cardiac surgery patients. Perfusion, 21(6), pp. 353-60. London: Sage 10.1177/0267659106074004

Gorrasi, J; Takala, J; Jakob, S (2006). The vascular bed during critical illness: evaluation in animal models. In: , (ed.) (119-128.). Heidelberg: Springer Verlag

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