Kaufmann, Thomas

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Hagmann, B R; Odermatt, A; Kaufmann, Thomas; Dahinden, C A; Fux, M (2017). Balance between IL-3 and type Iinterferons and their interrelationship with FasL dictates lifespan and effector functions of human basophils. Clinical and experimental allergy, 47(1), pp. 71-84. Wiley 10.1111/cea.12850


Wicki, Simone; Gurzeler, Ursina; Wei-Lynn Wong, W; Bachmann, Daniel; Kaufmann, Thomas; Jost, Philipp (2016). Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils. Cell death & disease, 7(10), e2422. Nature Publishing Group 10.1038/cddis.2016.311

Tuzlak, Selma; Kaufmann, Thomas; Villunger, Andreas (2016). Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis. Genes & development, 30(19), pp. 2133-2151. Cold Spring Harbor Laboratory Press 10.1101/gad.289298.116

Fernandez Marrero, Yuniel; Spinner, S; Jost, P J; Kaufmann, Thomas (2016). Survival control of malignant lymphocytes by anti-apoptotic MCL-1. Leukemia, 30(11), pp. 2152-2159. Nature Publishing Group 10.1038/leu.2016.213

D'Orsi, Beatrice; Engel, Tobias; Pfeiffer, Shona; Nandi, Saheli; Kaufmann, Thomas; Henshall, David C; Prehn, Jochen H M (2016). Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury. Journal of neuroscience, 36(16), pp. 4564-4578. Society for Neuroscience 10.1523/JNEUROSCI.3780-15.2016

Fernandez Marrero, Yuniel; Ke, Francine; Echeverry, Nohemy; Bouillet, Philippe; Bachmann, Daniel; Strasser, Andreas; Kaufmann, Thomas (2016). Is BOK required for apoptosis induced by endoplasmic reticulum stress? Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(5), E492-E493. National Academy of Sciences NAS 10.1073/pnas.1516347113

Amini, Poorya; Stojkov, Darko; Wang, Xiaoliang; Wicki, Simone; Kaufmann, Thomas; Wong, Wendy Wei-Lynn; Simon, Hans-Uwe; Yousefi, Shida (2016). NET formation can occur independently of RIPK3 and MLKL signaling. European journal of immunology, 46(1), pp. 178-184. Wiley-VCH 10.1002/eji.201545615

Reinhart, Ramona; Wicki, Simone; Kaufmann, Thomas (2016). In Vitro Differentiation of Mouse Granulocytes. Methods in molecular biology, 1419, pp. 95-107. Humana Press 10.1007/978-1-4939-3581-9_8


Yousefi, Shida; Morshed, Md. Mahbubul; Amini, Poorya; Stojkov, Darko; Simon, Dagmar; von Gunten, Stephan; Kaufmann, Thomas; Simon, Hans-Uwe (2015). Basophils exhibit antibacterial activity through extracellular trap formation. Allergy, 70(9), pp. 1184-1188. Wiley-Blackwell 10.1111/all.12662

Rozman, Sasa; Yousefi, Shida; Oberson, Kevin; Kaufmann, Thomas; Benarafa, Charaf; Simon, Hans-Uwe (2015). The generation of neutrophils in the bone marrow is controlled by autophagy. Cell death and differentiation, 22(3), pp. 445-456. Nature Publishing Group 10.1038/cdd.2014.169

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Targeting disease by immunomodulation. Cell death and differentiation, 22(2), pp. 185-186. Nature Publishing Group 10.1038/cdd.2014.166

Kaufmann, Thomas; Simon, Hans-Uwe (2015). Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell death and differentiation, 22(1), pp. 58-73. Nature Publishing Group 10.1038/cdd.2014.137

Kaufmann, Thomas; Reinhart, Ramona; Wicki, Simone (2015). In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols (In Press). In: Puthalakath, Hamsa; Hawkins, Christine (eds.) Programmed Cell Death: Methods and Protocols. Methods in Molecular Biology. Humana Press


Andree, Maria; Seeger, Jens M.; Schüll, Stephan; Coutelle, Oliver; Wagner-Stippich, Diana; Wiegmann, Katja; Wunderlich, Claudia M.; Birkmann, Kerstin; Broxtermann, Pia; Witt, Axel; Fritsch, Melanie; Martinelli, Paola; Bielig, Harald; Lamkemeyer, Tobias; Rugarli, Elena I.; Kaufmann, Thomas; Sterner-Kock, Anja; Wunderlich, F. Thomas; Villunger, Andreas; Martins, L. Miguel; ... (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. EMBO journal, 33(19), pp. 2171-2187. Nature Publishing Group 10.15252/embj.201387244

Morshed, Md. Mahbubul; Hlushchuk, Ruslan; Simon, Dagmar; Walls, Andrew F.; Obata-Ninomiya, Kazushige; Karasuyama, Hajime; Djonov, Valentin; Eggel, Alexander; Kaufmann, Thomas; Simon, Hans-Uwe; Yousefi, Shida (2014). NADPH oxidase-independent formation of extracellular DNA traps by basophils. Journal of immunology, 192(11), pp. 5314-5323. American Association of Immunologists 10.4049/jimmunol.1303418

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Weber, Benjamin; Schuster, Steffen; Zysset, Daniel; Rihs, Silvia; Dickgreber, Nina; Schürch, Christian; Riether, Carsten; Siegrist, Mark; Schneider, Christoph; Pawelski, Helga; Gurzeler, Ursina; Ziltener, Pascal; Genitsch, Vera; Tacchini-Cottier, Fabienne; Ochsenbein, Adrian; Hofstetter, Willy; Kopf, Manfred; Kaufmann, Thomas; Oxenius, Annette; Reith, Walter; ... (2014). TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS pathogens, 10(1), e1003900. Public Library of Science 10.1371/journal.ppat.1003900

Yabal, Monica; Müller, Nicole; Adler, Heiko; Knies, Nathalie; Gross, Christina J.; Damgaard, Rune Busk; Kanegane, Hirokazu; Ringelhan, Marc; Kaufmann, Thomas; Heikenwächter, Mathias; Strasser, Andreas; Gross, Olaf; Ruland, Jürgen; Peschel, Christian; Gyrd-Hansen, Mads; Jost, Philipp J. (2014). XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation. Cell reports, 7(6), pp. 1795-1808. Cell Press 10.1016/j.celrep.2014.05.008


Herold, Marco J.; Rohrbeck, Leona; Lang, Mathias J.; Grumont, Raelene; Gerondakis, Steve; Tai, Lin; Bouillet, Philippe; Kaufmann, Thomas; Strasser, Andreas (2013). Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein. EMBO REPORTS, 14(11), pp. 992-998. Nature 10.1038/embor.2013.152

Kretzschmar, Lydia; van den Borne, Bart H. P.; Kaufmann, Thomas; Reist, Martin; Strabel, D.; Harisberger, Myriam; Steiner, Adrian; Bodmer, Michèle (2013). [Mastitis management in Swiss dairy farms with udder health problems]. Schweizer Archiv für Tierheilkunde, 155(8), pp. 453-462. Huber 10.1024/0036-7281/a000491

Schulman, Jacqualyn J; Wright, Fiorrest A; Kaufmann, Thomas; Wojcikiewicz, Richard J H (2013). The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage. Journal of biological chemistry, 288(35), pp. 25340-25349. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.496570

Ke, Francine; Kaufmann, Thomas; Bouillet, Philippe; Strasser, Andreas; Kerr, Jeffrey; Voss, Anne K (2013). Consequences of the combined loss of BOK and BAK or BOK and BAX. Cell death & disease, 4(6), e650. Nature Publishing Group 10.1038/cddis.2013.176

Räber, R.; Kaufmann, Thomas; Regula, Gertraud; von Rotz, A.; Stoffel, Michael Hubert; Posthaus, Horst; Rérat, M.; Morel, I.; Kirchhofer, Marc; Steiner, Adrian; Bähler, Corinne (2013). Effects of different types of solid feeds on health status and performance of Swiss veal calves. II. Basic feeding with whole milk. Schweizer Archiv für Tierheilkunde, 155(5), pp. 283-292. Huber 10.1024/0036-7281/a000459

Räber, B.; Kaufmann, Thomas; Regula, Gertraud; von Rotz, Alois; Stoffel, Michael Hubert; Posthaus, Horst; Rérat, M.; Kirchhofer, M.; Steiner, Adrian; Bähler, Corinne (2013). Effects of different types of solid feeds on health status and performance of Swiss veal calves. I. Basic feeding with milk by-products. Schweizer Archiv für Tierheilkunde, 155(5), pp. 269-281. Huber 10.1024/0036-7281/a000458

Echeverry, Nohemy; Bachmann, Daniel; Ke, Francine; Strasser, Andreas; Simon, Hans-Uwe; Kaufmann, Thomas (2013). Intracellular localization of the BCL-2 family member BOK and functional implications. Cell death and differentiation, 20(6), pp. 785-799. Nature Publishing Group 10.1038/cdd.2013.10

Gurzeler, Ursina; Rabachini de Almeida, Tatiana; Dahinden, Clemens A.; Salmanidis, Marika; Brumati, Gabriela; Ekert, Paul G.; Echeverry, Nohemy; Bachmann, Daniel; Simon, Hans-Uwe; Kaufmann, Thomas (2013). In vitro differentiation of near-unlimited numbers of functional mouse basophils using conditional Hoxb8. Allergy, 5(68), pp. 604-613. Wiley-Blackwell 10.1111/all.12140


Luginbühl, A.; Bähler, C.; Steiner, A.; Kaufmann, Th.; Regula, G.; Ewy, A. (2012). Results of herd health management in veal calf production. Schweizer Archiv für Tierheilkunde, 154(7), pp. 277-285. Huber 10.1024/0036-7281/a000347

Bähler, Corinne; Steiner, Adrian; Luginbühl, A.; Ewy, A.; Posthaus, Horst; Strabel, D.; Kaufmann, Thomas; Regula, Gertraud (2012). Risk factors for death and unwanted early slaughter in Swiss veal calves kept at a specific animal welfare standard. Research in veterinary science, 92(1), pp. 162-168. Association for Veterinary Teaching and Research Work 10.1016/j.rvsc.2010.10.009

Kaufmann, Thomas; Strasser, Andreas; Jost, Philipp J (2012). Fas death receptor signalling: roles of Bid and XIAP. Cell death and differentiation, 19(1), pp. 42-50. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.121

Badmann, Anastasia; Langsch, Stephanie; Keogh, Adrian; Brunner, Thomas; Kaufmann, Thomas; Corazza, Nadia (2012). TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner. Cell death & disease, 3, e447. London: Nature Publishing Group 10.1038/cddis.2012.185

Corazza, Nadia; Kaufmann, Thomas (2012). Novel insights into mechanisms of food allergy and allergic airway inflammation using experimental mouse models. Allergy, 67(12), pp. 1483-90. Oxford: Wiley-Blackwell 10.1111/all.12065

Damgaard, Rune Busk; Nachbur, Ueli; Yabal, Monica; Wong, Wendy Wei-Lynn; Fiil, Berthe Katrine; Kastirr, Mischa; Rieser, Eva; Rickard, James Arthur; Bankovacki, Aleksandra; Peschel, Christian; Ruland, Juergen; Bekker-Jensen, Simon; Mailand, Niels; Kaufmann, Thomas; Strasser, Andreas; Walczak, Henning; Silke, John; Jost, Philipp J; Gyrd-Hansen, Mads (2012). The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Molecular cell, 46(6), pp. 746-58. Cambridge, Mass.: Cell Press 10.1016/j.molce1.2012.04.014

Ke, Francine; Voss, Anne; Kerr, Jeffrey; O'Reilly, Lorraine; Tai, Lin; Echeverry, Nohemy; Bouillet, Philippe; Strasser, Andreas; Kaufmann, Thomas (2012). BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice. Cell death and differentiation, 19(6), pp. 915-25. Basingstoke: Nature Publishing Group 10.1038/cdd.2011.210

von Gunten, Stephan; Kaufmann, Thomas (2012). Glucocorticoids 'on air'. Allergy, 67(2), pp. 144-6. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02778.x


Badmann, A.; Keough, A.; Kaufmann, T.; Bouillet, P.; Brunner, T.; Corazza, N. (2011). Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage. Cell death & disease, 2, e171. London: Nature Publishing Group 10.1038/cddis.2011.55

Geering, Barbara; Gurzeler, Ursina; Federzoni, Elena; Kaufmann, Thomas; Simon, Hans-Uwe (2011). A novel TNFR1-triggered apoptosis pathway mediated by class IA PI3Ks in neutrophils. Blood, 117(22), pp. 5953-5962. Washington, D.C.: American Society of Hematology 10.1182/blood-2010-11-322206

Kirchhofer, M.; Kaufmann, T.; Guelat-Brechbuhl, M.; Michel, A.; Syring, C.; Bodmer, M. (2011). [Systematic sanitation of dairy herds with mastitis caused by Staphylococcus aureus]. Schweizer Archiv für Tierheilkunde, 153(8), pp. 361-8. Bern: Huber 10.1024/0036-7281/a000222

Feyer, D.; Kemper, D.; Reist, M.; Kaufmann, T. (2011). Bluetongue disease: impact of the 2008 vaccination on fertility in supervised dairy herds. Schweizer Archiv für Tierheilkunde, 153(6), pp. 257-62. Bern: Huber 10.1024/0036-7281/a000199

Pfister, P.; Kaufmann, T.; Fellay, E.; Hirsbrunner, G. (2011). [Reproductive performance in Herens cows from 2003 to 2007]. Schweizer Archiv für Tierheilkunde, 153(1), pp. 7-13. Bern: Huber 10.1024/0036-7281/a000136


Jost, Philipp J; Kaufmann, Thomas (2010). Cancer caused by too much apoptosis--an intriguing contradiction? Hepatology, 51(4), pp. 1110-1112. Hoboken, N.J.: Wiley Interscience 10.1002/hep.23314

Graber, M.; Kohler, S.; Kaufmann, T.; Doherr, M.G.; Bruckmaier, R.M.; van Dorland, H.A. (2010). A field study on characteristics and diversity of gene expression in the liver of dairy cows during the transition period. Journal of dairy science, 93(11), pp. 5200-15. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2010-3265

Guelat-Brechbuehl, M.; Thomann, A.; Albini, S.; Moret-Stalder, S.; Reist, M.; Bodmer, M.; Michel, A.; Niederberger, M.D.; Kaufmann, T. (2010). Cross-sectional study of Streptococcus species in quarter milk samples of dairy cows in the canton of Bern, Switzerland. Veterinary record, 167(6), pp. 211-5. London: British Veterinary Association 10.1136/vr.c4237

Pfister, P.; Kaufmann, T. (2010). Osteomalazie als Bestandsproblem in einer Ziegenherde. Tierärztliche Praxis. Ausgabe G - Grosstiere, Nutztiere(5), pp. 321-325. Stuttgart: Schattauer

Tschuor, A.C.; Kaufmann, T.; Strabel, D.; Hassig, M. (2010). [Investigation of abortions and other animal health problems in relation to vaccination against Bluetongue virus in 2009]. Schweizer Archiv für Tierheilkunde, 152(11), pp. 501-6. Bern: Huber 10.1024/0036-7281/a000115

Wyder, A.B.; Boss, R.; Naskova, J.; Kaufmann, T.; Steiner, A.; Graber, H.U. (2010). Streptococcus spp. and related bacteria: Their identification and their pathogenic potential for chronic mastitis - A molecular approach. Research in veterinary science, 91(3), pp. 349-357. London: Association for Veterinary Teaching and Research Work 10.1016/j.rvsc.2010.09.006


Jost, Philipp J; Grabow, Stephanie; Gray, Daniel; McKenzie, Mark D; Nachbur, Ueli; Huang, David C S; Bouillet, Philippe; Thomas, Helen E; Borner, Christoph; Silke, John; Strasser, Andreas; Kaufmann, Thomas (2009). XIAP discriminates between type I and type II FAS-induced apoptosis. Nature, 460(7258), pp. 1035-1039. London: Macmillan Journals Ltd. 10.1038/nature08229

Bianchi, K; Jost, P J; Kaufmann, T; Rutkowski, R (2009). International EMBO Workshop on 'Model Organisms in Cell Death Research', Obergurgl (Austria). Cell death and differentiation, 16(8), pp. 1180-3. Basingstoke: Nature Publishing Group 10.1038/cdd.2009.60

O'Reilly, Lorraine A; Kruse, Elizabeth A; Puthalakath, Hamsa; Kelly, Priscilla N; Kaufmann, Thomas; Huang, David C S; Strasser, Andreas (2009). MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. Journal of immunology, 183(1), pp. 261-9. Bethesda, Md.: American Association of Immunologists 10.4049/jimmunol.0803853

Kaufmann, Thomas; Jost, Philipp J; Pellegrini, Marc; Puthalakath, Hamsa; Gugasyan, Raffi; Gerondakis, Steve; Cretney, Erika; Smyth, Mark J; Silke, John; Hakem, Razq; Bouillet, Philippe; Mak, Tak W; Dixit, Vishva M; Strasser, Andreas (2009). Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. Immunity, 30(1), pp. 56-66. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2008.10.017

Jabbour, A M; Heraud, J E; Daunt, C P; Kaufmann, T; Sandow, J; O'Reilly, L A; Callus, B A; Lopez, A; Strasser, A; Vaux, D L; Ekert, P G (2009). Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim. Cell death and differentiation, 16(4), pp. 555-63. Basingstoke: Nature Publishing Group 10.1038/cdd.2008.179

Moret-Stalder, S.; Fournier, C.; Miserez, R.; Albini, S.; Doherr, M.G.; Reist, M.; Schaeren, W.; Kirchhofer, M.; Graber, H.U.; Steiner, A.; Kaufmann, T. (2009). Prevalence study of Staphylococcus aureus in quarter milk samples of dairy cows in the Canton of Bern, Switzerland. Preventive veterinary medicine, 88(1), pp. 72-6. Amsterdam: Elsevier 10.1016/j.prevetmed.2008.06.020

Danuser, R.; Vogt, H.R.; Kaufmann, T.; Peterhans, E.; Zanoni, R. (2009). Seroprevalence and characterization of pestivirus infections in small ruminants and new world camelids in Switzerland. Schweizer Archiv für Tierheilkunde, 151(3), pp. 109-17. Bern: Huber 10.1024/0036-7281.151.3.109

Graber, H.U.; Naskova, J.; Studer, E.; Kaufmann, T.; Kirchhofer, M.; Brechbuhl, M.; Schaeren, W.; Steiner, A.; Fournier, C. (2009). Mastitis-related subtypes of bovine Staphylococcus aureus are characterized by different clinical properties. Journal of dairy science, 92(4), pp. 1442-51. Savoy, Ill.: American Dairy Science Association 10.3168/jds.2008-1430


Fournier, Christine; Kuhnert, Peter; Frey, Joachim; Miserez, Raymond François; Kirchhofer, Marc Peter; Kaufmann, Thomas; Steiner, Adrian; Graber, Hans Ulrich (2008). Bovine Staphylococcus aureus: association of virulence genes, genotypes and clinical outcome. Research in veterinary science, 85(3), pp. 439-448. London: Association for Veterinary Teaching and Research Work 10.1016/j.rvsc.2008.01.010

Walter, Dorothée; Schmich, Kathrin; Vogel, Sandra; Pick, Robert; Kaufmann, Thomas; Hochmuth, Florian Christoph; Haber, Angelika; Neubert, Karin; McNelly, Sabine; von Weizsäcker, Fritz; Merfort, Irmgard; Maurer, Ulrich; Strasser, Andreas; Borner, Christoph (2008). Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes. Hepatology, 48(6), pp. 1942-53. Hoboken, N.J.: Wiley Interscience 10.1002/hep.22541

McKenzie, Mark D; Carrington, Emma M; Kaufmann, Thomas; Strasser, Andreas; Huang, David C S; Kay, Thomas W H; Allison, Janette; Thomas, Helen E (2008). Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells. Diabetes, 57(5), pp. 1284-92. Alexandria, Va.: American Diabetes Association 10.2337/db07-1692


Strabel, D; Ewy, A; Kaufmann, T; Steiner, A; Kirchhofer, M (2007). [Rumenocentesis: a suitable technique for analysis of rumen juice pH in cattle?]. Schweizer Archiv für Tierheilkunde, 149(7), pp. 301-6. Bern: Huber 10.1024/0036-7281.149.7.301

Gloor, M; Kaufmann, T; Peterhans, E; Zanoni, R; Steiner, A; Kirchhofer, M (2007). [Heifer breeding farms as a source for spreading the BVD virus?]. Schweizer Archiv für Tierheilkunde, 149(8), pp. 345-51. Bern: Huber 10.1024/0036-7281.149.8.345

Kirchhofer, M; Tavel, L v; Strabel, D; Fournier, C; Steiner, A; Graber, H U; Kaufmann, T (2007). [Herd problem: udder health. Retrospective study of farms assessed by the Swiss Bovine Health Service (BHS) from 1999 to 2004]. DTW. Deutsche tierärztliche Wochenschrift, 114(9), pp. 338-44. Alfeld: Verlag M. & H. Schaper 10.2377/0341-6593-114-338

Brechbühl, M; Meylan, M; Kirchhofer, C; Kaufmann, T (2007). Haemolytic anaemia in Swiss dairy cows. Cattle practice, 3(15), p. 276. Fretherne: British Cattle Veterinary Association

Bodmer, M; Kaufmann, T; Zanoni, R; Steiner, A (2007). A BVD Free Communal Alpine Pasture in Switzerland. Cattle practice, 3(15), p. 294. Fretherne: British Cattle Veterinary Association

Kaufmann, T; Moret-Stalder, S; Steiner, A (2007). CMT und individuelle Milch-Zellzahl entscheiden, ob eine Milchprobe sinnvoll ist. In: Vet Med Report, Tagung der Deutschen Buiatrischen Gesellschaft.

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