Leichtle, Alexander Benedikt

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Pfortmueller, Carmen A; Lindner, Gregor; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Exadaktylos, Aristomenis K (2017). Role of D-Dimer testing in venous thromboembolism with concomitant renal insufficiency in critical care. Intensive care medicine, 43(3), pp. 470-471. Springer 10.1007/s00134-016-4646-3

Haider, Dominik; Klemenz, Thomas; Fiedler, Martin; Nakas, Christos T.; Exadaktylos, Aristomenis; Leichtle, Alexander Benedikt (2017). High sensitive cardiac troponin T: Testing the test. International journal of cardiology, 228, pp. 779-783. Elsevier 10.1016/j.ijcard.2016.10.043

Zinkernagel, Martin; Zysset-Burri, Denise Corinne; Keller, Irene; Berger, Lieselotte Erika; Leichtle, Alexander Benedikt; Largiadèr, Carlo Rodolfo; Fiedler, Martin; Wolf, Sebastian (2017). Association of the Intestinal Microbiome with the Development of Neovascular Age-Related Macular Degeneration. Scientific Reports, 7(40826), p. 40826. Nature Publishing Group 10.1038/srep40826


Sauter, Thomas; Ziegenhorn, Stephan; Ahmad, Sufian; Hautz, Wolf; Ricklin, Meret; Leichtle, Alexander Benedikt; Fiedler, Martin; Haider, Dominik; Exadaktylos, Aristomenis (2016). Age is not associated with intracranial haemorrhage in patients with mild traumatic brain injury and oral anticoagulation. Journal of negative results in biomedicine, 15(1), p. 12. BioMed Central 10.1186/s12952-016-0055-y

Dhayat, Nasser; Ackermann, Daniel; Pruijm, Menno; Ponte, Belen; Ehret, Georg; Guessous, Idris; Leichtle, Alexander Benedikt; Paccaud, Fred; Mohaupt, Markus; Fiedler, Martin; Devuyst, Olivier; Pechère-Bertschi, Antoinette; Burnier, Michel; Martin, Pierre-Yves; Bochud, Murielle; Vogt, Bruno; Fuster, Daniel Guido (2016). Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function. Kidney international, 90(3), pp. 648-657. Elsevier 10.1016/j.kint.2016.04.024

Haider, Dominik; Lindner, Gregor; Wolzt, Michael; Leichtle, Alexander Benedikt; Fiedler, Martin; Sauter, Thomas; Fuhrmann, Valentin; Exadaktylos, Aristomenis (2016). Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study. Journal of negative results in biomedicine, 15(1), p. 1. BioMed Central 10.1186/s12952-016-0044-1

Pichler Hefti, Jacqueline Renée; Leichtle, Alexander Benedikt; Stutz, Monika; Hefti, Urs; Geiser, Thomas; Huber, Andreas R; Merz, Tobias Michael (2016). Increased endothelial microparticles and oxidative stress at extreme altitude. European journal of applied physiology, 116(4), pp. 739-748. Springer 10.1007/s00421-015-3309-3

Bally, Lia; Züger, Thomas; Stettler, Christoph; Leichtle, Alexander Benedikt (2016). Computed exercise plasma lactate concentrations: A conversion formula. Practical Laboratory Medicine, 4, pp. 11-15. Elsevier 10.1016/j.plabm.2015.11.002

Lesche, Dorothea; Geyer, Roland; Lienhard, Daniel; Nakas, Christos T.; Diserens, Gaëlle; Vermathen, Peter; Leichtle, Alexander Benedikt (2016). Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome. Metabolomics, 12(10), p. 159. Springer 10.1007/s11306-016-1109-3

Pfortmueller, Carmen Andrea; Drexel, Christian; Krähenmann-Müller, Simone; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2016). S-100 B Concentrations Are a Predictor of Decreased Survival in Patients with Major Trauma, Independently of Head Injury. PLoS ONE, 11(3), e0152822. Public Library of Science 10.1371/journal.pone.0152822

Nakas, Christos T.; Schütz, Narayan; Werners, Marcus; Leichtle, Alexander Benedikt (2016). Accuracy and Calibration of Computational Approaches for Inpatient Mortality Predictive Modeling. PLoS ONE, 11(7), e0159046. Public Library of Science 10.1371/journal.pone.0159046


Studer, Martina; Goeggel Simonetti, Barbara; Heinks Maldonado, Theda; Steinlin, Maja; Leichtle, Alexander Benedikt; Berger, Steffen Michael; Joeris, Alexander (2015). Acute S100B in serum is associated with cognitive symptoms and memory performance 4 months after paediatric mild traumatic brain injury. Brain injury, 29(13-14), pp. 1667-1673. Informa Healthcare 10.3109/02699052.2015.1075250

Lindner, G; Heldner, Mirjam Rachel; Bernasconi, Corrado Angelo; Funk, G C; Arnold, Marcel; Schwarz, C; Leichtle, Alexander Benedikt; Fiedler, Martin; Gralla, Jan; Mattle, Heinrich; Exadaktylos, Aristomenis; Fischer, Urs (2015). Prevalence of dysnatremias and their implication on outcome during acute ischemic stroke and transient ischemic attack: A cross-sectional analysis. International journal of stroke, 10(Suppl 2), p. 241. Blackwell Publishing

Haider, Dominik; Lindner, Gregor; Ahmad, Sufian; Sauter, Thomas; Wolzt, Michael; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Fuhrmann, Valentin (2015). Hypermagnesemia is a strong independent risk factor for mortality in critically ill patients: results from a cross-sectional study. European journal of internal medicine, 26(7), pp. 504-507. Pozzi 10.1016/j.ejim.2015.05.013

Leichtle, Alexander Benedikt; Findeisen, Peter (2015). 7.7 Biobanking. In: Guder, Walter G.; Narayanan, Sheshadri (eds.) Pre-examination Procedures in Laboratory Diagnostics. Preanalytical Aspects and their Impact on the Quality of Medical Laboratory Results (pp. 328-334). Berlin: De Gruyter 10.1515/9783110334043-038

Sauter, Thomas; Lindner, Gregor; Ahmad, Sufian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Haider, Dominik (2015). Calcium Disorders in the Emergency Department: Independent Risk Factors for Mortality. PLoS ONE, 10(7), e0132788. Public Library of Science 10.1371/journal.pone.0132788

Pfortmüller, Carmen; Pauchard-Neuwerth, Sandra Elisabeth; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Lindner, Gregor (2015). Primary Hyperventilation in the Emergency Department: A First Overview. PLoS ONE, 10(6), e0129562. Public Library of Science 10.1371/journal.pone.0129562

Pfortmüller, Carmen; Drexel, C; Krähenmann-Müller, S; Leichtle, Alexander Benedikt; Fiedler, Martin; Lindner, G; Exadaktylos, AK (2015). S-100 B Concentrations Are a Predictor of Decreased Survival in Patients With Major Trauma Independently of Head Injury. Intensive care medicine experimental, 3(Suppl 1), A31. Springer 10.1186/2197-425X-3-S1-A31

Leichtle, Alexander Benedikt (2015). Biomarker – vom Sein und Wesen. LaboratoriumsMedizin / Journal of laboratory medicine, 39(2), pp. 97-101. De Gruyter 10.1515/labmed-2015-0033

Haider, Dominik; Lindner, Gregor; Wolzt, Michael; Ahmad, Sufian S; Sauter, Thomas; Leichtle, Alexander Benedikt; Fiedler, Georg-Martin; Fuhrmann, Valentin; Exadaktylos, Aristomenis (2015). Hyperphosphatemia Is an Independent Risk Factor for Mortality in Critically Ill Patients: Results from a Cross-Sectional Study. PLoS ONE, 10(8), e0133426. Public Library of Science 10.1371/journal.pone.0133426


Lindner, G; Funk, G-C; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christa; Eleftheriadis, T; Pasch, Andreas; Mohaupt, Markus; Exadaktylos, Aristomenis; Arampatzis, Spyridon (2014). Impact of proton pump inhibitor use on magnesium homoeostasis: a cross-sectional study in a tertiary emergency department. International Journal of Clinical Practice, 68(11), pp. 1352-1357. Wiley 10.1111/ijcp.12469

Lindner, Gregor; Funk, Georg-Christian; Pfortmüller, Carmen; Leichtle, Alexander B.; Fiedler, Georg M.; Schwarz, Christoph; Exadaktylos, Aristomenis K.; Puig, Stefan (2014). D-dimer to Rule Out Pulmonary Embolism in Renal Insufficiency. American journal of medicine, 127(4), pp. 343-347. Elsevier 10.1016/j.amjmed.2013.12.003

Dysli, Chantal-Simone; Quellec, Gwénolé; Abegg, Mathias; Menke, Marcel N; Wolf-Schnurrbusch, Ute; Kowal, Horst Jens; Blatz, Johannes; La Schiazza, Olivier; Leichtle, Alexander Benedikt; Wolf, Sebastian; Zinkernagel, Martin S (2014). Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects. Investigative ophthalmology & visual science, 55(4), pp. 2106-2113. Association for Research in Vision and Ophthalmology 10.1167/iovs.13-13627

Pfortmüller, Carmen; Wiemann, Christoph; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis; Lindner, Gregor (2014). Hypoglycemia is associated with increased mortality in patients with acute decompensated liver cirrhosis. Journal of critical care, 29(2), 316.e7-316.e12. Elsevier 10.1016/j.jcrc.2013.11.002

Pfortmüller, Carmen; Lindner, Gregor; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2014). Diagnostic significance of high sensitivity troponin in diagnosis of blunt cardiac injury. Intensive care medicine, 40(4), pp. 623-624. Springer 10.1007/s00134-013-3204-5

Pfortmüller, Carmen A.; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Exadaktylos, Aristomenis; Lindner, Gregor (2014). Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis. PLoS ONE, 9(3), e92150. Public Library of Science 10.1371/journal.pone.0092150

Lindner, Gregor; Pfortmüller, Carmen; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2014). Age-related variety in electrolyte levels and prevalence of dysnatremias and dyskalemias in patients presenting to the emergency department. Gerontology, 60(5), pp. 420-423. Karger 10.1159/000360134


Mai, Manuel; Tönjes, Anke; Kovacs, Peter; Stumvoll, Michael; Fiedler, Georg Martin; Leichtle, Alexander Benedikt (2013). Serum Levels of Acylcarnitines Are Altered in Prediabetic Conditions. PLoS ONE, 8(12), e82459. Public Library of Science 10.1371/journal.pone.0082459

Pfortmueller, Carmen A.; Funk, Georg-Christian; Marti, Grischa; Leichtle, Alexander B.; Fiedler, Georg M.; Schwarz, Christoph; Exadaktylos, Aristomenis K.; Lindner, Gregor (2013). Diagnostic performance of high-sensitive troponin T in patients with renal insufficiency. American journal of cardiology, 112(12), pp. 1968-1972. Elsevier 10.1016/j.amjcard.2013.08.028

Lindner, Gregor; Felber, Rainer; Schwarz, Christoph; Marti, Grischa; Leichtle, Alexander Benedikt; Fiedler, Martin; Zimmermann, Heinz; Arampatzis, Spyridon; Exadaktylos, Aristomenis Konstantinos (2013). Hypercalcemia in the ED: prevalence, etiology, and outcome. American journal of emergency medicine, 31(4), pp. 657-60. Philadelphia, Pa.: W.B. Saunders 10.1016/j.ajem.2012.11.010

Euteneuer, Sara; Yang, Kuo H; Chavez, Eduardo; Leichtle, Anke; Loers, Gabriele; Olshansky, Adel; Pak, Kwang; Schachner, Melitta; Ryan, Allen F (2013). Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM). Molecular and cellular neuroscience, 54, pp. 30-43. San Diego, Calif.: Elsevier 10.1016/j.mcn.2012.12.004

Leichtle, Alexander Benedikt; Ceglarek, U; Weinert, P; Nakas, C T; Nuoffer, Jean-Marc; Kase, J; Conrad, T; Witzigmann, H; Thiery, J; Fiedler, Martin (2013). Pancreatic carcinoma, pancreatitis, and healthy controls: metabolite models in a three-class diagnostic dilemma. Metabolomics, 9(3), pp. 677-687. New York, N.Y.: Springer 10.1007/s11306-012-0476-7

Marti, Grischa; Schwarz, Christoph; Leichtle, Alexander Benedikt; Fiedler, Martin; Arampatzis, Spyridon; Exadaktylos, Aristomenis; Lindner, Gregor (2013). Etiology and symptoms of severe hypokalemia in emergency department patients. European journal of emergency medicine, 21(1), pp. 46-51. London: Lippincott Williams & Wilkins

Arampatzis, Spyridon; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Schwarz, Christoph; Zimmermann, Heinz; Exadaktylos, Aristomenis; Lindner, Gregor (2013). Impact of diuretic therapy-associated electrolyte disorders present on admission to the emergency department: a cross-sectional analysis. BMC medicine, 11, p. 83. London: BioMed Central 10.1186/1741-7015-11-83

Lindner, Gregor; Pfortmüller, Carmen; Funk, Georg-Christian; Leichtle, Alexander Benedikt; Fiedler, Martin; Exadaktylos, Aristomenis (2013). High-Sensitive Troponin Measurement in Emergency Department Patients Presenting with Syncope: A Retrospective Analysis. PLoS ONE, 8(6), e66470. Public Library of Science 10.1371/journal.pone.0066470

Leichtle, Alexander Benedikt; Dufour, Jean-François; Fiedler, Martin (2013). Potentials and pitfalls of clinical peptidomics and metabolomics. Swiss medical weekly, 143, w13801. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13801


Leichtle, Alexander Benedikt; Nuoffer, Jean-Marc; Ceglarek, Uta; Kase, Julia; Conrad, Tim; Witzigmann, Helmut; Thiery, Joachim; Fiedler, Georg Martin (2012). Serum amino acid profiles and their alterations in colorectal cancer. Metabolomics, 8(4), pp. 643-653. New York, N.Y.: Springer 10.1007/s11306-011-0357-5

Schwarz, Christoph; Leichtle, Alexander Benedikt; Arampatzis, Spiros; Fiedler, Georg Martin; Zimmermann, Heinz; Exadaktylos, Aristomenis Konstantinos; Lindner, Gregor (2012). Thyroid function and serum electrolytes: does an association really exist? Swiss medical weekly, 142, w13669. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2012.13669

Arampatzis, Spyridon; Frauchiger, Bettina; Fiedler, Georg-Martin; Leichtle, Alexander Benedikt; Buhl, Daniela; Schwarz, Christoph; Funk, Georg-Christian; Zimmermann, Heinz; Exadaktylos, Aristomenis K; Lindner, Gregor (2012). Characteristics, symptoms, and outcome of severe dysnatremias present on hospital admission. American journal of medicine, 125(11), 1125.e1-1125.e7. Orlando, Fla.: Elsevier 10.1016/j.amjmed.2012.04.041


Leichtle, Alexander B; Helmschrodt, Christin; Ceglarek, Uta; Shai, Iris; Henkin, Yaakov; Schwarzfuchs, Dan; Golan, Rachel; Gepner, Yftach; Stampfer, Meir J; Blüher, Matthias; Stumvoll, Michael; Thiery, Joachim; Fiedler, Georg M (2011). Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men. American journal of clinical nutrition, 94(5), pp. 1189-95. Bethesda, Md.: American Society for Nutrition, Inc. 10.3945/ajcn.111.018119

Schumann, Julia; Leichtle, Alexander; Thiery, Joachim; Fuhrmann, Herbert (2011). Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264.7 macrophages. PLoS ONE, 6(8), e24066. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0024066

Brauer, Romy; Leichtle, Alexander Benedikt; Fiedler, Georg Martin; Thiery, Joachim; Ceglarek, Uta (2011). Preanalytical standardization of amino acid and acylcarnitine metabolite profiling in human blood using tandem mass spectrometry. Metabolomics, 7(3), pp. 344-352. New York, N.Y.: Springer 10.1007/s11306-010-0256-1

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