Müller, Joachim

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2016

Aguado Martinez, Adriana; Silva Pinto Basto, Afonso; Müller, Joachim; Balmer, Vreni; Manser, Vera; Leitão, Alexandre; Hemphill, Andrew (2016). N-terminal fusion of a toll-like receptor 2-ligand to a Neospora caninum chimeric antigen efficiently modifies the properties of the specific immune response. Parasitology, 143(5), pp. 606-616. Cambridge University Press 10.1017/S0031182016000056

Hemphill, Andrew; Aguado Martinez, Adriana; Müller, Joachim (2016). Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models. Parasitology, 143(3), pp. 245-259. Cambridge University Press 10.1017/S0031182015001596

Müller, Joachim; Aguado Martinez, Adriana; Manser, Vera; Wong, Ho Ning; Haynes, Richard K; Hemphill, Andrew (2016). Repurposing of antiparasitic drugs: the hydroxy-naphthoquinone buparvaquone inhibits vertical transmission in the pregnant neosporosis mouse model. Veterinary research, 47, p. 32. BioMed Central 10.1186/s13567-016-0317-1

2015

Küster, Tatiana; Stadelmann, Britta; Rufener, Reto; Risch, Corina; Müller, Joachim; Hemphill, Andrew (2015). Oral treatments of Echinococcus multilocularis-infected mice with the antimalarial drug mefloquine that potentially interacts with parasite ferritin and cystatin. International journal of antimicrobial agents, 46(5), pp. 546-551. Elsevier 10.1016/j.ijantimicag.2015.07.016

Winzer, Pablo Arnold; Müller, Joachim; Aguado Martinez, Adriana; Rahman, Mahbubur; Balmer, Vreni; Manser, Vera; Ortega-Mora, Luis Miguel; Ojo, Kayode K; Fan, Erkang; Maly, Dustin J; Van Voorhis, Wesley C; Hemphill, Andrew (2015). In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum. Antimicrobial agents and chemotherapy, 59(10), pp. 6361-6374. American Society for Microbiology 10.1128/AAC.01236-15

Müller, Joachim; Rout, Samuel; Leitsch, David; Vaithilingam, Jathana; Hehl, Adrian; Müller, Norbert (2015). Comparative characterisation of two nitroreductases from Giardia lamblia as potential activators of nitro compounds. International Journal for Parasitology: Drugs and Drug Resistance, 5(2), pp. 37-43. Elsevier 10.1016/j.ijpddr.2015.03.001

Arranz Solis, David; Aguado Martinez, Adriana; Müller, Joachim; Regidor-Cerrillo, Javier; Ortega-Mora, Luis Miguel; Hemphill, Andrew (2015). Dose-dependent effects of experimental infection with the virulent Neospora caninum Nc-Spain7 isolate in a pregnant mouse model. Veterinary parasitology, 211(3-4), pp. 133-140. Elsevier 10.1016/j.vetpar.2015.05.021

Müller, Joachim; Balmer, Vreni; Winzer, Pablo Arnold; Rahman, Mahbubur; Manser, Vera; Haynes, Richard K; Hemphill, Andrew (2015). In vitro effects of new artemisinin derivatives in Neospora caninum-infected human fibroblasts. International journal of antimicrobial agents, 46(1), pp. 88-93. Elsevier 10.1016/j.ijantimicag.2015.02.020

Müller, Joachim; Aguado Martinez, Adriana; Manser, Vera; Balmer, Vreni; Winzer, Pablo Arnold; Ritler, Dominic; Hostettler, Isabel; Arranz Solis, David; Ortega-Mora, Luis; Hemphill, Andrew (2015). Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice. International Journal for Parasitology: Drugs and Drug Resistance, 5(1), pp. 16-25. Elsevier 10.1016/j.ijpddr.2015.02.001

2014

Hostettler, Isabel; Müller, Joachim; Stephens, Chad E; Haynes, Richard; Hemphill, Andrew (2014). A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts. International Journal for Parasitology: Drugs and Drug Resistance, 4(3), pp. 201-209. Elsevier 10.1016/j.ijpddr.2014.09.003

Stadelmann, Britta; Aeschbacher, Denise; Huber, Cristina; Spiliotis, Markus; Müller, Joachim; Hemphill, Andrew (2014). Profound activity of the anti-cancer drug bortezomib against Echinococcus multilocularis metacestodes identifies the proteasome as a novel drug target for cestodes. PLoS neglected tropical diseases, 8(12), e3352. Public Library of Science 10.1371/journal.pntd.0003352

Hemphill, Andrew; Stadelmann, Britta; Rufener, Reto; Spiliotis, Markus; Boubaker, Ghalia; Müller, Joachim; Müller, Norbert; Gorgas, Daniela; Gottstein, Bruno (2014). Treatment of echinococcosis: albendazole and mebendazole - what else? Parasite, 21, p. 70. Princeps Editions 10.1051/parasite/2014073

Müller, Joachim; Vaithilingam, Jathana; Rosner, Judah Lee; Müller, Norbert (2014). Escherichia coli are susceptible to thiazolides if the tolc efflux system is inhibited. Journal of Developing Drugs, 3(2), p. 1000124. OMICS Group 10.4172/2329-6631.1000124

Ojo, Kayode K; Reid, Molly C; Kallur Siddaramaiah, Latha; Müller, Joachim; Winzer, Pablo Arnold; Zhang, Zhongsheng; Keyloun, Katelyn R; Vidadala, Rama Subba Rao; Merritt, Ethan A; Hol, Wim G J; Maly, Dustin J; Fan, Erkang; Van Voorhis, Wesley C; Hemphill, Andrew (2014). Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapy. PLoS ONE, 9(3), e92929. Public Library of Science 10.1371/journal.pone.0092929

2013

Müller, Joachim; Schildknecht, Patricia; Müller, Norbert (2013). Metabolism of nitro drugs metronidazole and nitazoxanide in Giardia lamblia: characterization of a novel nitroreductase (GlNR2). Journal of antimicrobial chemotherapy, 68(8), pp. 1781-1789. Oxford University Press 10.1093/jac/dkt106

Hemphill, Andrew; Debache, Karim; Monney, Thierry; Schorer, Michelle; Gouinaud, Christophe; Alaeddine, Ferial; Müller, Norbert; Müller, Joachim (2013). Proteins mediating the Neospora caninum-host cell interaction as targets for vaccination. Frontiers in Bioscience (Elite Edition), 5, pp. 23-36. Frontiers in Bioscience

Hemphill, Andrew; Müller, Norbert; Müller, Joachim (2013). Thiazolides, a Novel Class of Anti-Infective Drugs, Effective Against Viruses, Bacteria, Intracellular and Extracellular Protozoan Parasites and Proliferating Mammalian Cells. Anti-infective agents in medicinal chemistry, 11(1), pp. 22-30. Bentham Science 10.2174/22113626130103

2012

Reinmann, Karin; Müller, Norbert; Kuhnert, Peter; Campero, Carlos M.; Leitsch, David; Hess, M; Henning, K; Fort, M; Müller, Joachim; Gottstein, Bruno; Frey, Caroline (2012). Tritrichomonas foetus isolates from cats and cattle show minor genetic differences in unrelated loci ITS-2 and EF-1alpha. Veterinary parasitology, 185(2-4), pp. 138-44. Amsterdam: Elsevier 10.1016/j.vetpar.2011.09.032

2011

Nillius, Dorothea; Müller, Joachim; Müller, Norbert (2011). Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs. Journal of antimicrobial chemotherapy, 66(5), pp. 1029-35. Oxford: Oxford University Press 10.1093/jac/dkr029

2009

Schmuckli-Maurer, Jacqueline; Casanova, Carlo; Schmied, Stéfanie; Affentranger, Sarah; Parvanova, Iana; Kang'a, Simon; Nene, Vishvanath; Katzer, Frank; McKeever, Declan; Müller, Joachim; Bishop, Richard; Pain, Arnab; Dobbelaere, Dirk; Rodrigues, Mauricio Martins (2009). Expression Analysis of the Theileria parva Subtelomere-Encoded Variable Secreted Protein Gene Family. PLoS ONE, 4(3), e4839. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0004839

Müller, Joachim; Nillius, Dorothea; Hehl, A.; Hemphill, Andrew; Müller, Norbert (2009). Stable expression of Escherichia coli beta-glucuronidase A (GusA) in Giardia lamblia: application to high-throughput drug susceptibility testing. Journal of antimicrobial chemotherapy, 64(6), pp. 1187-1191. Oxford: Oxford University Press 10.1093/jac/dkp363

2008

Müller, Joachim; Ley, Serej; Felger, Ingrid; Hemphill, Andrew; Müller, Norbert (2008). Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole. Journal of antimicrobial chemotherapy, 62(1), pp. 72-82. Oxford University Press 10.1093/jac/dkn142

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