Reubi, Jean-Claude

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2017

Wan, Ming Young Simon; Endozo, Raymond; Michopoulou, Sofia; Shortman, Robert; Rodriguez-Justo, Manuel; Menezes, Leon; Yusuf, Syed; Richards, Toby; Wild, Damian; Waser, Beatrice; Reubi, Jean-Claude; Groves, Ashley (2017). PETCT Imaging of Unstable Carotid Plaque with Ga-68 labelled Somatostatin Receptor Ligand. Journal of nuclear medicine, 58(5), pp. 774-780. Society of Nuclear Medicine 10.2967/jnumed.116.181438

Popp, Ilinca; Del Pozzo, Luigi; Waser, Beatrice; Reubi, Jean-Claude; Meyer, Philipp T; Maecke, Helmut R; Gourni, Eleni (2017). Approaches to improve metabolic stability of a statine-based GRP receptor antagonist. Nuclear medicine and biology, 45, pp. 22-29. Elsevier 10.1016/j.nucmedbio.2016.11.004

2016

Reubi, Jean-Claude; Waser, Beatrice; Maecke, Helmut R; Rivier, Jean E (2016). HIGHLY INCREASED 125I-JR11 ANTAGONIST BINDING IN VITRO REVEALS NOVEL INDICATIONS FOR SST2 TARGETING IN HUMAN CANCERS. Journal of nuclear medicine, 58(2), pp. 300-306. Society of Nuclear Medicine 10.2967/jnumed.116.177733

Rylova, Svetlana N; Waser, Beatrice; Del Pozzo, Luigi; Tönnesmann, Roswitha; Mansi, Rosalba; Meyer, Philipp T; Reubi, Jean-Claude; Maecke, Helmut R (2016). Approaches to Improve the Pharmacokinetics of Radiolabeled Glucagon-Like Peptide-1 Receptor Ligands Using Antagonistic Tracers. Journal of nuclear medicine, 57(8), pp. 1282-1288. Society of Nuclear Medicine 10.2967/jnumed.115.168948

2015

Gourni, Eleni; Del Pozzo, Luigi; Kheirallah, Emilie; Smerling, Christiane; Waser, Beatrice; Reubi, Jean-Claude; Paterson, Brett M; Donnelly, Paul S; Meyer, Philipp T; Maecke, Helmut R (2015). Copper-64 Labeled Macrobicyclic Sarcophagine Coupled to a GRP Receptor Antagonist Shows Great Promise for PET Imaging of Prostate Cancer. Molecular Pharmaceutics, 12(8), pp. 2781-2790. American Chemical Society 10.1021/mp500671j

Antwi, Kwadwo; Fani, Melpomeni; Nicolas, Guillaume; Rottenburger, Christof; Heye, Tobias; Reubi, Jean-Claude; Gloor, Beat; Christ, Emanuel; Wild, Damian (2015). Localization of Hidden Insulinomas with 68Ga-DOTA-Exendin-4 PET/CT: A Pilot Study. Journal of nuclear medicine, 56(7), pp. 1075-1078. Society of Nuclear Medicine 10.2967/jnumed.115.157768

Kolenc Peitl, Petra; Tamma, MariaLuisa; Kroselj, Marko; Braun, Friederike; Waser, Beatrice; Reubi, Jean-Claude; Sollner Dolenc, Marija; Maecke, Helmut R; Mansi, Rosalba (2015). Stereochemistry of Amino Acid Spacers Determines the Pharmacokinetics of (111)In-DOTA-Minigastrin Analogues for Targeting the CCK2/Gastrin Receptor. Bioconjugate chemistry, 26(6), pp. 1113-1119. American Chemical Society 10.1021/acs.bioconjchem.5b00187

Christ, Emanuel; Wild, Damian; Antwi, Kwadwo; Waser, Beatrice; Fani, Melpomeni; Schwanda, Stefanie; Heye, Tobias; Schmid, Christoph; Baer, Hans Ulrich; Perren, Aurel; Reubi, Jean-Claude (2015). Preoperative localization of adult nesidioblastosis using (68)Ga-DOTA-exendin-4-PET/CT. Endocrine, 50(3), pp. 821-823. Springer 10.1007/s12020-015-0633-7

Reubi, Jean-Claude; Waser, Beatrice (2015). Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs. Journal of nuclear medicine, 56(4), pp. 613-615. Society of Nuclear Medicine 10.2967/jnumed.114.153189

Mansi, Rosalba; Abiraj, Keelara; Wang, Xuejuan; Tamma, Maria Luisa; Gourni, Eleni; Cescato, Renzo; Berndt, Sandra; Reubi, Jean-Claude; Maecke, Helmut R (2015). Evaluation of three different families of bombesin receptor radioantagonists for targeted imaging and therapy of gastrin releasing peptide receptor (GRP-R) positive tumors. Journal of medicinal chemistry, 58(2), pp. 682-691. American Chemical Society 10.1021/jm5012066

Körner Jachertz, Meike; Waser, Beatrice; Strobel, Oliver; Büchler, Markus; Reubi, Jean-Claude (2015). Neurotensin receptors in pancreatic ductal carcinomas. EJNMMI research, 5(17), p. 17. Springer 10.1186/s13550-015-0094-2

Körner Jachertz, Meike; Waser, Beatrice; Reubi, Jean-Claude (2015). Does somatostatin or gastric inhibitory peptide receptor expression correlate with tumor grade and stage in gut neuroendocrine tumors? Neuroendocrinology, 101(1), pp. 45-57. Karger 10.1159/000371804

2014

Reubi, Jean-Claude (2014). Strict rules are needed for validation of G-protein-coupled receptor immunohistochemical studies in human tissues. Endocrine, 47(3), pp. 659-661. Springer 10.1007/s12020-014-0320-0

Gourni, Eleni; Mansi, Rosalba; Jamous, Mazen; Waser, Beatrice; Smerling, Christiane; Burian, Antje; Buchegger, Franz; Reubi, Jean-Claude; Maecke, Helmut R (2014). N-terminal modifications improve the receptor affinity and pharmacokinetics of radiolabeled peptidic gastrin-releasing peptide receptor antagonists: examples of 68Ga- and 64Cu-labeled peptides for PET imaging. Journal of nuclear medicine, 55(10), pp. 1719-1725. Society of Nuclear Medicine 10.2967/jnumed.114.141242

Waser, Beatrice; Blank, Annika; Karamitopoulou, Evanthia; Perren, Aurel; Reubi, Jean-Claude (2014). Glucagon-like-peptide-1 receptor expression in normal and diseased human thyroid and pancreas. Modern pathology, 28(3), pp. 391-402. Nature Publishing Group 10.1038/modpathol.2014.113

Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Tatsi, Aikaterini; Kaloudi, Aikaterini; Krenning, Eric P; de Jong, Marion; Nock, Berthold A; Reubi, Jean-Claude (2014). [111In-DOTA]LTT-SS28, a first pansomatostatin radioligand for in vivo targeting of somatostatin receptor-positive tumors. Journal of medicinal chemistry, 57(15), pp. 6564-6571. American Chemical Society 10.1021/jm500581d

Jamous, Mazen; Tamma, Maria L; Gourni, Eleni; Waser, Beatrice; Reubi, Jean-Claude; Maecke, Helmut R; Mansi, Rosalba (2014). PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists. Nuclear medicine and biology, 41(6), pp. 464-470. Elsevier 10.1016/j.nucmedbio.2014.03.014

Wild, Damian; Fani, Melpomeni; Fischer, Richard; Del Pozzo, Luigi; Kaul, Felix; Krebs, Simone; Fischer, Richard; Rivier, Jean E F; Reubi, Jean-Claude; Maecke, Helmut R; Weber, Wolfgang A (2014). Comparison of Somatostatin Receptor Agonist and Antagonist for Peptide Receptor Radionuclide Therapy: A Pilot Study. Journal of nuclear medicine, 55(8), pp. 1248-1252. Society of Nuclear Medicine 10.2967/jnumed.114.138834

Waser, Beatrice; Reubi, Jean-Claude (2014). Radiolabelled GLP-1 receptor antagonist binds to GLP-1 receptor-expressing human tissues. European journal of nuclear medicine and molecular imaging, 41(6), pp. 1166-1171. Springer 10.1007/s00259-013-2684-4

Gourni, Eleni; Waser, Beatrice; Clerc, Pascal; Fourmy, Daniel; Reubi, Jean-Claude; Maecke, Helmut R (2014). The Glucose-Dependent Insulinotropic Polypeptide Receptor: A Novel Target for Neuroendocrine Tumor Imaging-First Preclinical Studies. Journal of nuclear medicine, 55(6), pp. 976-982. Society of Nuclear Medicine 10.2967/jnumed.113.133744

Mikkola, Kirsi; Yim, Cheng-Bin; Fagerholm, Veronica; Ishizu, Tamiko; Elomaa, Viki-Veikko; Rajander, Johan; Jurttila, Jori; Saanijoki, Tiina; Tolvanen, Tuula; Tirri, Marko; Gourni, Eleni; Béhé, Martin; Gotthardt, Martin; Reubi, Jean-Claude; Mäcke, Helmut; Roivainen, Anne; Solin, Olof; Nuutila, Pirjo (2014). Erratum to: (64)Cu- and (68)Ga-Labelled [Nle (14),Lys (40)(Ahx-NODAGA)NH 2]-Exendin-4 for Pancreatic Beta Cell Imaging in Rats. Molecular imaging and biology, 16(2), p. 293. Springer 10.1007/s11307-013-0700-5

Mikkola, Kirsi; Kirsi, Mikkola; Yim, Cheng-Bin; Cheng-Bin, Yim; Fagerholm, Veronica; Veronica, Fagerholm; Ishizu, Tamiko; Tamiko, Ishizu; Elomaa, Viki-Veikko; Viki-Veikko, Elomaa; Rajander, Johan; Johan, Rajander; Jurttila, Jori; Jori, Jurttila; Saanijoki, Tiina; Tiina, Saanijoki; Tolvanen, Tuula; Tuula, Tolvanen; Tirri, Marko; Marko, Tirri; ... (2014). 64Cu- and 68Ga-labelled [Nle(14),Lys(40)(Ahx-NODAGA)NH2]-exendin-4 for pancreatic beta cell imaging in rats. Molecular imaging and biology, 16(2), pp. 255-263. Springer 10.1007/s11307-013-0691-2

Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean-Claude; Nock, Berthold A (2014). [DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting. European journal of medicinal chemistry, 73, pp. 30-37. Elsevier Masson SAS 10.1016/j.ejmech.2013.12.003

Körner Jachertz, Meike; Waser, Beatrice; Rehmann, Ruth; Reubi, Jean-Claude (2014). Early over-expression of GRP receptors in prostatic carcinogenesis. Prostate, 74(2), pp. 217-224. Wiley-Blackwell 10.1002/pros.22743

Komor, Jan; Reubi, Jean-Claude; Christ, Emanuel R. (2014). Peptide receptor radionuclide therapy in a patient with disabling non-functioning pituitary adenoma. Pituitary, 17(3), pp. 227-231. Springer Science + Business Media 10.1007/s11102-013-0494-0

Wieser, Gesche; Mansi, Rosalba; Grosu, Anca L; Schultze-Seemann, Wolfgang; Dumont-Walter, Rebecca A; Meyer, Philipp T; Maecke, Helmut R; Reubi, Jean-Claude; Weber, Wolfgang A (2014). Positron emission tomography (PET) imaging of prostate cancer with a gastrin releasing peptide receptor antagonist - from mice to men. Theranostics, 4(4), pp. 412-419. Ivyspring International 10.7150/thno.7324

Wicki, Andreas; Wild, Damian; Prêtre, Vincent; Mansi, Rosalba; Orleth, Annette; Reubi, Jean-Claude; Rochlitz, Christoph; Mamot, Christoph; Mäcke, Helmut R; Christofori, Gerhard (2014). Synergism of peptide receptor-targeted Auger electron radiation therapy with anti-angiogenic compounds in a mouse model of neuroendocrine tumors. EJNMMI research, 4(1), p. 9. Springer 10.1186/2191-219X-4-9

2013

Reubi, Jean-Claude; Schonbrunn, Agnes (2013). Illuminating somatostatin analog action at neuroendocrine tumor receptors. Trends in Pharmacological Sciences, 34(12), pp. 676-688. Elsevier 10.1016/j.tips.2013.10.001

Sparr, Christof; Purkayastha, Nirupam; Yoshinari, Tomohiro; Seebach, Dieter; Maschauer, Simone; Prante, Olaf; Hübner, Harald; Gmeiner, Peter; Kolesinska, Beata; Cescato, Renzo; Waser, Beatrice; Reubi, Jean-Claude (2013). Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments. Chemistry & Biodiversity, 10(12), pp. 2101-2121. Verlag Helvetica Chimica Acta 10.1002/cbdv.201300331

Christ, Emanuel; Wild, Damian; Ederer, Susanne; Béhé, Martin; Nicolas, Guillaume; Caplin, Martyn E.; Brändle, Michael; Clerici, Thomas; Fischli, Stefan; Stettler, Christoph; Ell, Peter J.; Seufert, Jochen; Gloor, Beat; Perren, Aurel; Reubi, Jean-Claude; Forrer, Flavio (2013). Glucagon-like peptide-1 receptor imaging for the localisation of insulinomas: a prospective multicentre imaging study. The Lancet Diabetes & Endocrinology, 1(2), pp. 115-122. The Lancet Publishing Group 10.1016/S2213-8587(13)70049-4

Dumont, Rebecca A.; Tamma, MariaLuisa; Braun, Friederike; Borkowski, Sandra; Reubi, Jean-Claude; Maecke, Helmut; Weber, Wolfgang A.; Mansi, Rosalba (2013). Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin. Journal of nuclear medicine, 54(5), pp. 762-769. Society of Nuclear Medicine 10.2967/jnumed.112.112169

Mansi, Rosalba; Fleischmann, Achim; Mäcke, Helmut R.; Reubi, Jean-Claude (2013). Targeting GRPR in urological cancers--from basic research to clinical application. Nature Reviews. Urology, 10(4), pp. 235-244. Nature Publishing Group 10.1038/nrurol.2013.42

Wild, Damian; Bomanji, Jamshed B.; Benkert, Pascal; Maecke, Helmut; Ell, Peter J.; Reubi, Jean-Claude; Caplin, Martyn E. (2013). Comparison of 68Ga-DOTANOC and 68Ga-DOTATATE PET/CT within patients with gastroenteropancreatic neuroendocrine tumors. Journal of nuclear medicine, 54(3), pp. 364-372. Society of Nuclear Medicine 10.2967/jnumed.112.111724

Körner Jachertz, Meike; Reubi, Jean-Claude (2013). Somatostatin/NPY. In: Kastin, Abba J. (ed.) Handbook of Biologically Active Peptides, 2nd ed. (pp. 548-555). Amsterdam: Elsevier

2012

Waser, Beatrice; Rehmann, Ruth; Sanchez, Claire; Fourmy, Daniel; Reubi, Jean Claude (2012). Glucose-dependent insulinotropic polypeptide receptors in most gastroenteropancreatic and bronchial neuroendocrine tumors. Journal of clinical endocrinology and metabolism, 97(2), pp. 482-8. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-2454

Sanchez, Claire; Escrieut, Chantal; Clerc, Pascal; Gigoux, Véronique; Waser, Beatrice; Reubi, Jean Claude; Fourmy, Daniel (2012). Characterization of a novel five-transmembrane domain cholecystokinin-2 receptor splice variant identified in human tumors. Molecular and cellular endocrinology, 349(2), pp. 170-9. Shannon: Elsevier Ireland 10.1016/j.mce.2011.10.010

von Guggenberg, Elisabeth; Rangger, Christine; Sosabowski, Jane; Laverman, Peter; Reubi, Jean-Claude; Virgolini, Irene Johanna; Decristoforo, Clemens (2012). Preclinical Evaluation of Radiolabeled DOTA-Derivatized Cyclic Minigastrin Analogs for Targeting Cholecystokinin Receptor Expressing Malignancies. Molecular imaging and biology, 14(3), pp. 366-75. New York, N.Y.: Springer 10.1007/s11307-011-0506-2

Win, Thida; Screaton, Nicholas J; Porter, Joanna; Endozo, Raymondo; Wild, Damian; Kayani, Irfan; Dickson, John; Shortman, Robert I; Reubi, Jean C; Ell, Peter J; Groves, Ashley M (2012). Novel positron emission tomography/computed tomography of diffuse parenchymal lung disease combining a labeled somatostatin receptor analogue and 2-deoxy-2[¹⁸F]fluoro-D-glucose. Molecular imaging, 11(2), pp. 91-8. Hamilton, Ont.: Decker 10.1097/00005382-199621000-00001

Waser, Beatrice; Cescato, Renzo; Liu, Qisheng; Kao, Yachu J; Körner, Meike; Christ, Emanuel; Schonbrunn, Agnes; Reubi, Jean Claude (2012). Phosphorylation of sst2 receptors in neuroendocrine tumors after octreotide treatment of patients. American journal of pathology, 180(5), pp. 1942-9. New York, N.Y.: Elsevier 10.1016/j.ajpath.2012.01.041

Körner, Meike; Waser, Beatrice; Schonbrunn, Agnes; Perren, Aurel; Reubi, Jean Claude (2012). Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. The American journal of surgical pathology, 36(2), pp. 242-52. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/PAS.0b013e31823d07f3

Körner, Meike; Christ, Emanuel; Wild, Damian; Reubi, Jean Claude (2012). Glucagon-like peptide-1 receptor overexpression in cancer and its impact on clinical applications. Frontiers in endocrinology, 3, p. 158. Lausanne: Frontiers Research Foundation 10.3389/fendo.2012.00158

Körner, Meike; Rehmann, Ruth; Reubi, Jean Claude (2012). GLP-2 receptors in human disease: high expression in gastrointestinal stromal tumors and Crohn's disease. Molecular and cellular endocrinology, 364(1-2), pp. 46-53. Shannon: Elsevier Ireland 10.1016/j.mce.2012.08.008

Zhang, Hanwen; Abiraj, Keelara; Thorek, Daniel L. J.; Waser, Beatrice; Smith-Jones, Peter M.; Honer, Michael; Reubi, Jean Claude; Maecke, Helmut R. (2012). Evolution of bombesin conjugates for targeted PET imaging of tumors. PLoS ONE, 7(9), e44046. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0044046

Nock, Berthold A; Cescato, Renzo; Ketani, Eleni; Waser, Beatrice; Reubi, Jean Claude; Maina, Theodosia (2012). [(99m)Tc]Demomedin C, a radioligand based on human gastrin releasing peptide(18-27): synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models. Journal of medicinal chemistry, 55(19), pp. 8364-74. Easton, Pa.: American Chemical Society 10.1021/jm300741f

Wang, Xuejuan; Fani, Melpomeni; Schulz, Stefan; Rivier, Jean; Reubi, Jean Claude; Maecke, Helmut R (2012). Comprehensive evaluation of a somatostatin-based radiolabelled antagonist for diagnostic imaging and radionuclide therapy. European journal of nuclear medicine and molecular imaging, 39(12), pp. 1876-85. Berlin: Springer 10.1007/s00259-012-2231-8

Fani, Melpomeni; Braun, Friederike; Waser, Beatrice; Beetschen, Karin; Cescato, Renzo; Erchegyi, Judit; Rivier, Jean E; Weber, Wolfgang A; Maecke, Helmut R; Reubi, Jean Claude (2012). Unexpected sensitivity of sst2 antagonists to N-terminal radiometal modifications. Journal of nuclear medicine, 53(9), pp. 1481-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.112.102764

Lee, Misu; Waser, Beatrice; Reubi, Jean-Claude; Pellegata, Natalia S (2012). Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Molecular endocrinology, 26(8), pp. 1394-405. Bethesda, Md.: Endocrine Society 10.1210/me.2012-1055

Tatsi, Aikaterini; Maina, Theodosia; Cescato, Renzo; Waser, Beatrice; Krenning, Eric P; de Jong, Marion; Cordopatis, Paul; Reubi, Jean Claude; Nock, Berthold A (2012). [111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study. EJNMMI research, 2(1), p. 25. Berlin: Springer 10.1186/2191-219X-2-25

2011

Allen, Camryn D; Waser, Beatrice; Körner, Meike; Reubi, Jean Claude; Lee, Soon; Rivier, Catherine (2011). Neuropeptide Y acts within the rat testis to inhibit testosterone secretion. Neuropeptides, 45(1), pp. 55-61. Amsterdam: Elsevier 10.1016/j.npep.2010.10.006

Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Waser, Beatrice; Cescato, Renzo; Graham, Keith; Borkowski, Sandra; Reubi, Jean Claude; Maecke, Helmut R (2011). Development of a potent DOTA-conjugated bombesin antagonist for targeting GRPr-positive tumours. European journal of nuclear medicine and molecular imaging, 38(1), pp. 97-107. Berlin: Springer 10.1007/s00259-010-1596-9

Wild, Damian; Christ, Emanuel; Caplin, Martyn E; Kurzawinski, Tom R; Forrer, Flavio; Brändle, Michael; Seufert, Jochen; Weber, Wolfgang A; Bomanji, Jamshed; Perren, Aurel; Ell, Peter J; Reubi, Jean Claude (2011). Glucagon-like peptide-1 versus somatostatin receptor targeting reveals 2 distinct forms of malignant insulinomas. Journal of nuclear medicine, 52(7), pp. 1073-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.085142

Zueger, Thomas; Buehler, Annette; Stalder, Mario; Walpoth, Nazan; Reubi, Jean Claude; Stettler, Christoph (2011). A rare localization of a neuroendocrine tumor. Journal of clinical endocrinology and metabolism, 96(6), pp. 1625-6. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2011-0124

Reubi, Jean Claude; Fleischmann, Achim; Waser, Beatrice; Rehmann, Ruth (2011). Concomitant vascular GRP-receptor and VEGF-receptor expression in human tumors: molecular basis for dual targeting of tumoral vasculature. Peptides, 32(7), pp. 1457-62. New York, N.Y.: Elsevier 10.1016/j.peptides.2011.05.007

Körner, Meike; Waser, Beatriche; Thalmann, George N; Reubi, Jean Claude (2011). High expression of NPY receptors in the human testis. Molecular and cellular endocrinology, 337(1-2), pp. 62-70. Shannon: Elsevier Ireland 10.1016/j.mce.2011.01.021

Chatenet, David; Cescato, Renzo; Waser, Beatrice; Erchegyi, Judit; Rivier, Jean E; Reubi, Jean Claude (2011). Novel dimeric DOTA-coupled peptidic Y1-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers. European journal of nuclear medicine and molecular imaging, 1(1), p. 21. Berlin: Springer 10.1186/2191-219X-1-21

Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Fani, Melpomeni; Forrer, Flavio; Nicolas, Guillaume; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2011). Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors. Journal of nuclear medicine, 52(12), pp. 1970-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.094375

Cescato, Renzo; Waser, Beatrice; Fani, Melpomeni; Reubi, Jean Claude (2011). Evaluation of 177Lu-DOTA-sst2 antagonist versus 177Lu-DOTA-sst2 agonist binding in human cancers in vitro. Journal of nuclear medicine, 52(12), pp. 1886-90. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.095778

Waser, Beatrice; Beetschen, Karin; Pellegata, Natalia S; Reubi, Jean Claude (2011). Incretin receptors in non-neoplastic and neoplastic thyroid C cells in rodents and humans: relevance for incretin-based diabetes therapy. Neuroendocrinology, 94(4), pp. 291-301. Basel: Karger 10.1159/000330447

Wild, Damian; Fani, Melpomeni; Behe, Martin; Brink, Ingo; Rivier, Jean E F; Reubi, Jean Claude; Maecke, Helmut R; Weber, Wolfgang A (2011). First clinical evidence that imaging with somatostatin receptor antagonists is feasible. Journal of nuclear medicine, 52(9), pp. 1412-7. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.088922

Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E; Reubi, Jean Claude (2011). N-imidazolebenzyl-histidine substitution in somatostatin and in its octapeptide analogue modulates receptor selectivity and function. Journal of medicinal chemistry, 54(17), pp. 5981-7. Easton, Pa.: American Chemical Society 10.1021/jm200307v

Fourmy, Daniel; Gigoux, Véronique; Reubi, Jean Claude (2011). Gastrin in gastrointestinal diseases. Gastroenterology, 141(3), 814-818.e1-3. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2011.07.006

Fani, Melpomeni; Del Pozzo, Luigi; Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria Luisa; Cescato, Renzo; Waser, Beatrice; Weber, Wolfgang A; Reubi, Jean Claude; Maecke, Helmut R (2011). PET of somatostatin receptor-positive tumors using 64Cu- and 68Ga-somatostatin antagonists: the chelate makes the difference. Journal of nuclear medicine, 52(7), pp. 1110-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.111.087999

Maecke, Helmut R; Reubi, Jean Claude (2011). Somatostatin receptors as targets for nuclear medicine imaging and radionuclide treatment. Journal of nuclear medicine, 52(6), pp. 841-4. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.084236

Seebach, Dieter; Lukaszuk, Aneta; Patora-Komisarska, Krystyna; Podwysocka, Dominika; Gardiner, James; Ebert, Marc-Olivier; Reubi, Jean Claude; Cescato, Renzo; Waser, Beatrice; Gmeiner, Peter; Hübner, Harald; Rougeot, Catherine (2011). On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY. Chemistry & Biodiversity, 8(5), pp. 711-39. Zürich: Verlag Helvetica Chimica Acta 10.1002/cbdv.201100093

Ocak, Meltem; Helbok, Anna; Rangger, Christine; Peitl, Petra Kolenc; Nock, Berthold A; Morelli, Giancarlo; Eek, Annemarie; Sosabowski, Jane K; Breeman, Wout A P; Reubi, Jean Claude; Decristoforo, Clemens (2011). Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1426-35. Berlin: Springer 10.1007/s00259-011-1818-9

Aloj, Luigi; Aurilio, Michela; Rinaldi, Valentina; D'ambrosio, Laura; Tesauro, Diego; Peitl, Petra Kolenc; Maina, Theodosia; Mansi, Rosalba; von Guggenberg, Elisabeth; Joosten, Lieke; Sosabowski, Jane K; Breeman, Wouter A P; De Blois, Erik; Koelewijn, Stuart; Melis, Marleen; Waser, Beatrice; Beetschen, Karin; Reubi, Jean Claude; de Jong, Marion (2011). Comparison of the binding and internalization properties of 12 DOTA-coupled and ¹¹¹In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1417-25. Berlin: Springer 10.1007/s00259-011-1816-y

Laverman, Peter; Joosten, Lieke; Eek, Annemarie; Roosenburg, Susan; Peitl, Petra Kolenc; Maina, Theodosia; Mäcke, Helmut; Aloj, Luigi; von Guggenberg, Elisabeth; Sosabowski, Jane K; de Jong, Marion; Reubi, Jean-Claude; Oyen, Wim J G; Boerman, Otto C (2011). Comparative biodistribution of 12 ¹¹¹In-labelled gastrin/CCK2 receptor-targeting peptides. European journal of nuclear medicine and molecular imaging, 38(8), pp. 1410-6. Berlin: Springer 10.1007/s00259-011-1806-0

Kolenc-Peitl, Petra; Mansi, Rosalba; Tamma, MariaLuisa; Gmeiner-Stopar, Tanja; Sollner-Dolenc, Marija; Waser, Beatrice; Baum, Richard P; Reubi, Jean Claude; Maecke, Helmut R (2011). Highly improved metabolic stability and pharmacokinetics of indium-111-DOTA-gastrin conjugates for targeting of the gastrin receptor. Journal of medicinal chemistry, 54(8), pp. 2602-9. Easton, Pa.: American Chemical Society 10.1021/jm101279a

Wild, Damian; Frischknecht, Michael; Zhang, Hanwen; Morgenstern, Alfred; Bruchertseifer, Frank; Boisclair, Julie; Provencher-Bolliger, Anne; Reubi, Jean-Claude; Maecke, Helmut R (2011). Alpha- versus beta-particle radiopeptide therapy in a human prostate cancer model (213Bi-DOTA-PESIN and 213Bi-AMBA versus 177Lu-DOTA-PESIN). Cancer research, 71(3), pp. 1009-18. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-10-1186

Waser, Beatrice; Reubi, Jean Claude (2011). Value of the radiolabelled GLP-1 receptor antagonist exendin(9-39) for targeting of GLP-1 receptor-expressing pancreatic tissues in mice and humans. European journal of nuclear medicine and molecular imaging, 38(6), pp. 1054-8. Berlin: Springer 10.1007/s00259-010-1701-0

Wild, D; Reubi, JC (2011). Localisation d'in insulinome bénin par imagerie des récepteurs du glucagon-like peptide-1. Correspondances en MHDN - métabolismes hormones diabètes & nutrition, 8, pp. 296-297. Courbevoie (F): Edimark

Chatterjee, J; Laufer, B; Beck, JG; Helyes, Z; Pinter, E; Szolcsanyi, J; Horvath, A; Mandl, J; Reubi, JC; Keri, G; Kessler, H (2011). N-Methylated sst2 selective somatostatin cyclic peptide analogue as a potent candidate for treating neurogenic inflammation. ACS medicinal chemistry letters, 2(7), pp. 509-514. Washington, D.C.: American Chemical Society 10.1021/ml200032v

Chatenet, D; Cescato, R; Waser, B; Rivier, J; Reubi, JC (2011). Synthesis and characterization of DOTA-coupled dimeric Y1 receptors antagonists for breast cancer targeting. In: , (ed.) Proceeding of the 22nd American Peptide Symposium. American Peptide Society

2010

Kempná, Petra; Körner, Meike; Waser, Beatrice; Hofer, Gaby; Nuoffer, Jean-Marc; Reubi, Jean-Claude; Flück, Christa E. (2010). Neuropeptide Y modulates steroid production of human adrenal H295R cells through Y1 receptors. Molecular and cellular endocrinology, 314(1), pp. 101-109. Shannon: Elsevier Ireland 10.1016/j.mce.2009.08.010

Körner, Meike; Waser, Beatrice; Reubi, Jean-Claude; Miller, Laurence J. (2010). CCK2 receptor splice variant with intron 4 retention in human gastrointestinal and lung tumours. Journal of Cellular and Molecular Medicine, 14(4), pp. 933-943. Bucharest (Romania): Wiley 10.1111/j.1582-4934.2009.00859.x

Reubi, Jean Claude; Waser, Beatrice; Cescato, Renzo; Gloor, Beat; Stettler, Christoph; Christ, Emanuel (2010). Internalized somatostatin receptor subtype 2 in neuroendocrine tumors of octreotide-treated patients. Journal of clinical endocrinology and metabolism, 95(5), pp. 2343-50. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-2487

Reubi, J C; Perren, A; Rehmann, R; Waser, B; Christ, E; Callery, M; Goldfine, A B; Patti, M E (2010). Glucagon-like peptide-1 (GLP-1) receptors are not overexpressed in pancreatic islets from patients with severe hyperinsulinaemic hypoglycaemia following gastric bypass. Diabetologia, 53(12), pp. 2641-5. Heidelberg: Springer 10.1007/s00125-010-1901-y

Fani, Melpomeni; Mueller, Andreas; Tamma, Maria-Luisa; Nicolas, Guillaume; Rink, Hans R; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2010). Radiolabeled bicyclic somatostatin-based analogs: a novel class of potential radiotracers for SPECT/PET of neuroendocrine tumors. Journal of nuclear medicine, 51(11), pp. 1771-9. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.110.076695

Waser, Beatrice; Cescato, Renzo; Tamma, Maria-Luisa; Maecke, Helmut R; Reubi, Jean Claude (2010). Absence of somatostatin SST(2) receptor internalization in vivo after intravenous SOM230 application in the AR42J animal tumor model. European journal of pharmacology, 644(1-3), pp. 257-62. Amsterdam: Elsevier 10.1016/j.ejphar.2010.07.005

Reubi, Jean Claude; Erchegyi, Judit; Cescato, Renzo; Waser, Beatrice; Rivier, Jean E (2010). Switch from antagonist to agonist after addition of a DOTA chelator to a somatostatin analog. European journal of nuclear medicine and molecular imaging, 37(8), pp. 1551-8. Berlin: Springer 10.1007/s00259-010-1445-x

Abiraj, Keelara; Mansi, Rosalba; Tamma, Maria-Luisa; Forrer, Flavio; Cescato, Renzo; Reubi, Jean Claude; Akyel, Kayhan G; Maecke, Helmut R (2010). Tetraamine-derived bifunctional chelators for technetium-99m labelling: synthesis, bioconjugation and evaluation as targeted SPECT imaging probes for GRP-receptor-positive tumours. Chemistry - a European journal, 16(7), pp. 2115-24. Weinheim: Wiley-VCH 10.1002/chem.200902011

Cescato, Renzo; Loesch, Kimberly A; Waser, Beatrice; Mäcke, Helmut R; Rivier, Jean E; Reubi, Jean Claude; Schonbrunn, Agnes (2010). Agonist-biased signaling at the sst2A receptor: the multi-somatostatin analogs KE108 and SOM230 activate and antagonize distinct signaling pathways. Molecular endocrinology, 24(1), pp. 240-9. Bethesda, Md.: Endocrine Society 10.1210/me.2009-0321

Christ, Emanuel; Wild, Damian; Reubi, Jean Claude (2010). Glucagonlike peptide-1 receptor: an example of translational research in insulinomas: a review. Endocrinology and metabolism clinics of North America, 39(4), pp. 791-800. Philadelphia, Pa.: Elsevier 10.1016/j.ecl.2010.09.003

Shastry, Manu; Kayani, Irfan; Wild, Damian; Caplin, Martyn; Visvikis, Dimitris; Gacinovic, Svetislav; Reubi, Jean Claude; Bomanji, Jamshed B (2010). Distribution pattern of 68Ga-DOTATATE in disease-free patients. Nuclear medicine communications, 31(12), pp. 1025-32. London: Lippincott Williams & Wilkins 10.1097/MNM.0b013e32833f635e

Di Cianni, Alessandra; Carotenuto, Alfonso; Brancaccio, Diego; Novellino, Ettore; Reubi, Jean Claude; Beetschen, Karin; Papini, Anna Maria; Ginanneschi, Mauro (2010). Novel octreotide dicarba-analogues with high affinity and different selectivity for somatostatin receptors. Journal of medicinal chemistry, 53(16), pp. 6188-97. Easton, Pa.: American Chemical Society 10.1021/jm1005868

Laznickova, A; Laznicek, M; Trejtnar, F; Maecke, H R; Eisenwiener, K P; Reubi, J C (2010). Biodistribution of two octreotate analogs radiolabeled with indium and yttrium in rats. Anticancer research, 30(6), pp. 2177-84. Kapandriti: International Inst. of Anticancer Research

Oberg, Kjell E; Reubi, Jean-Claude; Kwekkeboom, Dik J; Krenning, Eric P (2010). Role of somatostatins in gastroenteropancreatic neuroendocrine tumor development and therapy. Gastroenterology, 139(3), 742-53, 753.e1. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2010.07.002

Wild, Damian; Theodoraki, Aikaterini; Kurzawinski, Tom R; Bomanji, Jamshed; Reubi, Jean Claude; Khan, Rehman; Bouloux, Pierre; Khoo, Bernard (2010). 'Running on empty'. European journal of nuclear medicine and molecular imaging, 37(7), pp. 1439-40. Berlin: Springer 10.1007/s00259-010-1455-8

Cordier, D; Forrer, F; Bruchertseifer, F; Morgenstern, A; Apostolidis, C; Good, S; Müller-Brand, J; Mäcke, H; Reubi, J C; Merlo, A (2010). Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial. European journal of nuclear medicine and molecular imaging, 37(7), pp. 1335-44. Berlin: Springer 10.1007/s00259-010-1385-5

Wa ngler, Carmen; Waser, Beatrice; Alke, Andrea; Iovkova, Ljuba; Buchholz, Hans-Georg; Niedermoser, Sabrina; Jurkschat, Klaus; Fottner, Christian; Bartenstein, Peter; Schirrmacher, Ralf; Reubi, Jean-Claude; Wester, Hans-Ju rgen; Wa ngler, Bjo rn (2010). One-Step (18)F-Labeling of Carbohydrate-Conjugated Octreotate-Derivatives Containing a Silicon-Fluoride-Acceptor (SiFA): In Vitro and in Vivo Evaluation as Tumor Imaging Agents for Positron Emission Tomography (PET). Bioconjugate chemistry, 21(12), pp. 2289-96. Washington, D.C.: American Chemical Society 10.1021/bc100316c

2009

Christ, Emanuel; Wild, Damian; Forrer, Flavio; Brändle, Michael; Sahli, Rahel; Clerici, Thomas; Gloor, Beat; Martius, Ferdinand; Maecke, Helmut; Reubi, Jean Claude (2009). Glucagon-like peptide-1 receptor imaging for localization of insulinomas. Journal of clinical endocrinology and metabolism, 94(11), pp. 4398-405. Chevy Chase, Md.: Endocrine Society 10.1210/jc.2009-1082

Mansi, Rosalba; Wang, Xuejuan; Forrer, Flavio; Kneifel, Stefan; Tamma, Maria-Luisa; Waser, Beatrice; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2009). Evaluation of a 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated bombesin-based radioantagonist for the labeling with single-photon emission computed tomography, positron emission tomography, and therapeutic radionuclides. Clinical cancer research, 15(16), pp. 5240-9. Philadelphia, Pa.: Association for Cancer Research 10.1158/1078-0432.CCR-08-3145

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2009). High expression of gastrin-releasing peptide receptors in the vascular bed of urinary tract cancers: promising candidates for vascular targeting applications. Endocrine-related cancer, 16(2), pp. 623-33. Bristol: BioScientifica Ltd. 10.1677/ERC-08-0316

Waser, Bea; Tamma, Maria-Luisa; Cescato, Renzo; Maecke, Helmut R; Reubi, Jean Claude (2009). Highly efficient in vivo agonist-induced internalization of sst2 receptors in somatostatin target tissues. Journal of nuclear medicine, 50(6), pp. 936-41. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.061457

Beierle, John M; Horne, W Seth; van Maarseveen, Jan H; Waser, Beatrice; Reubi, Jean Claude; Ghadiri, M Reza (2009). Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues. Angewandte Chemie (International ed.), 48(26), pp. 4725-9. Weinheim: Wiley-VCH 10.1002/anie.200805901

Erchegyi, Judit; Cescato, Renzo; Grace, Christy Rani R; Waser, Beatrice; Piccand, Véronique; Hoyer, Daniel; Riek, Roland; Rivier, Jean E; Reubi, Jean Claude (2009). Novel, potent, and radio-iodinatable somatostatin receptor 1 (sst1) selective analogues. Journal of medicinal chemistry, 52(9), pp. 2733-46. Easton, Pa.: American Chemical Society 10.1021/jm801314f

Akgün, Eyup; Körner Jachertz, Meike; Gao, Fan; Harikumar, Kaleeckal G; Waser, Beatrice; Reubi, Jean Claude; Portoghese, Philip S; Miller, Laurence J (2009). Synthesis and in vitro characterization of radioiodinatable benzodiazepines selective for type 1 and type 2 cholecystokinin receptors. Journal of medicinal chemistry, 52(7), pp. 2138-47. Easton, Pa.: American Chemical Society 10.1021/jm801439x

Feytens, Debby; De Vlaeminck, Magali; Cescato, Renzo; Tourwé, Dirk; Reubi, Jean Claude (2009). Highly potent 4-amino-indolo[2,3-c]azepin-3-one-containing somatostatin mimetics with a range of sst receptor selectivities. Journal of medicinal chemistry, 52(1), pp. 95-104. Easton, Pa.: American Chemical Society 10.1021/jm801205x

2008

Reubi, Jean Claude; Maecke, Helmut R (2008). Peptide-based probes for cancer imaging. Journal of nuclear medicine, 49(11), pp. 1735-8. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.108.053041

Wild, Damian; Mäcke, Helmut; Christ, Emanuel; Gloor, Beat; Reubi, Jean Claude (2008). Glucagon-like peptide 1-receptor scans to localize occult insulinomas. New England journal of medicine NEJM, 359(7), pp. 766-8. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMc0802045

Körner, Meike; Waser, Beatrice; Reubi, Jean Claude (2008). High expression of neuropeptide Y1 receptors in ewing sarcoma tumors. Clinical cancer research, 14(16), pp. 5043-9. Philadelphia, Pa.: Association for Cancer Research 10.1158/1078-0432.CCR-07-4551

Grace, Christy Rani R; Erchegyi, Judit; Reubi, Jean Claude; Rivier, Jean E; Riek, Roland (2008). Three-dimensional consensus structure of sst2-selective somatostatin (SRIF) antagonists by NMR. Biopolymers, 89(12), pp. 1077-87. Hoboken, N.J.: John Wiley & Sons, Inc. 10.1002/bip.21060

Körner, Meike; Reubi, Jean Claude (2008). Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors. Journal of neuropathology and experimental neurology, 67(8), pp. 741-9. Hagerstown, Md.: Lippincott Williams & Wilkins

Palii, Stela S; Afzal, Aqeela; Shaw, Lynn C; Pan, Hao; Caballero, Sergio; Miller, Rehae C; Jurczyk, Simona; Reubi, Jean-Claude; Tan, Yufei; Hochhaus, Guenther; Edelhauser, Henry; Geroski, Dayle; Shapiro, Gideon; Grant, Maria B (2008). Nonpeptide somatostatin receptor agonists specifically target ocular neovascularization via the somatostatin type 2 receptor. Investigative ophthalmology & visual science, 49(11), pp. 5094-102. Hagerstown, Md.: Association for Research in Vision and Ophthalmology 10.1167/iovs.08-2289

Good, Stephan; Walter, Martin A; Waser, Beatrice; Wang, Xuejuan; Müller-Brand, Jan; Béhé, Martin P; Reubi, Jean-Claude; Maecke, Helmut R (2008). Macrocyclic chelator-coupled gastrin-based radiopharmaceuticals for targeting of gastrin receptor-expressing tumours. European journal of nuclear medicine and molecular imaging, 35(10), pp. 1868-77. Berlin: Springer 10.1007/s00259-008-0803-4

Erchegyi, Judit; Grace, Christy Rani R; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size of somatostatin analogues (ODT-8) modulates receptor selectivity and binding affinity. Journal of medicinal chemistry, 51(9), pp. 2668-75. Easton, Pa.: American Chemical Society 10.1021/jm701444y

Grace, Christy Rani R; Erchegyi, Judit; Samant, Manoj; Cescato, Renzo; Piccand, Veronique; Riek, Roland; Reubi, Jean Claude; Rivier, Jean E (2008). Ring size in octreotide amide modulates differently agonist versus antagonist binding affinity and selectivity. Journal of medicinal chemistry, 51(9), pp. 2676-81. Easton, Pa.: American Chemical Society 10.1021/jm701445q

Ginj, Mihaela; Zhang, Hanwen; Eisenwiener, Klaus-Peter; Wild, Damian; Schulz, Stefan; Rink, Hans; Cescato, Renzo; Reubi, Jean Claude; Maecke, Helmut R (2008). New pansomatostatin ligands and their chelated versions: affinity profile, agonist activity, internalization, and tumor targeting. Clinical cancer research, 14(7), pp. 2019-27. Philadelphia, Pa.: Association for Cancer Research 10.1158/1078-0432.CCR-07-1687

Heppeler, Axel; André, João P; Buschmann, Ingeborg; Wang, Xuejuan; Reubi, Jean-Claude; Hennig, Michael; Kaden, Thomas A; Maecke, Helmut R (2008). Metal-ion-dependent biological properties of a chelator-derived somatostatin analogue for tumour targeting. Chemistry - a European journal, 14(10), pp. 3026-34. Weinheim: Wiley-VCH 10.1002/chem.200701264

Körner, Meike U; Hayes, Gregory M; Carrigan, Patricia E; Rehmann, Ruth; Miller, Laurence J; Reubi, Jean C (2008). Wild-type and splice-variant secretin receptors in lung cancer: overexpression in carcinoid tumors and peritumoral lung tissue. Modern pathology, 21(4), pp. 387-95. London: Nature Publishing Group 10.1038/modpathol.3801005

D'Addona, Debora; Carotenuto, Alfonso; Novellino, Ettore; Piccand, Véronique; Reubi, Jean Claude; Di Cianni, Alessandra; Gori, Francesca; Papini, Anna Maria; Ginanneschi, Mauro (2008). Novel sst5-selective somatostatin dicarba-analogues: synthesis and conformation-affinity relationships. Journal of medicinal chemistry, 51(3), pp. 512-20. Easton, Pa.: American Chemical Society 10.1021/jm070886i

Cescato, Renzo; Maina, Theodosia; Nock, Berthold; Nikolopoulou, Anastasia; Charalambidis, David; Piccand, Véronique; Reubi, Jean Claude (2008). Bombesin receptor antagonists may be preferable to agonists for tumor targeting. Journal of nuclear medicine, 49(2), pp. 318-26. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.107.045054

Gugger, Mathias; White, Richard; Song, Susan; Waser, Bea; Cescato, Renzo; Rivière, Pierre; Reubi, Jean Claude (2008). GPR87 is an overexpressed G-protein coupled receptor in squamous cell carcinoma of the lung. Disease markers, 24(1), pp. 41-50. Amsterdam: IOS Press 10.1155/2008/857474

Betzel, Thomas; Hess, Tobias; Waser, Beatrice; Reubi, Jean-C; Roesch, Frank (2008). closo-borane conjugated regulatory peptides retain high biological affinity: synthesis of closo-borane conjugated Tyr(3)-octreotate derivatives for BNCT. Bioconjugate chemistry, 19(9), pp. 1796-802. Washington, D.C.: American Chemical Society 10.1021/bc800101h

Cescato, Renzo; Erchegyi, Judith; Waser, Beatrice; Piccand, Véronique; Maecke, Helmut R; Rivier, Jean E; Reubi, Jean Claude (2008). Design and in vitro characterization of highly sst2-selective somatostatin antagonists suitable for radiotargeting. Journal of medicinal chemistry, 51(13), pp. 4030-7. Easton, Pa.: American Chemical Society 10.1021/jm701618q

Nikolopoulou, A; Nock, B; Petrou, C; Cordopatis, P; Reubi, JC; Maina, T (2008). Toward 99mTc-based somatostatins with high affinity for all five somatostatin receptor subtypes. In: Cordopatis PA, Manessi-Zoupa E (ed.) 5th Hellenic Forum on Bioactive Peptides (pp. 195-202). Typorama

Wild, D; Christ, E; Gloor, B; Mäcke, H; Reubi, JC (2008). Nuklearmedizin: Neue nuklearmedizinische Bildgebung zur Lokalisation von okkulten Insulinomen. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, 8(51-52), pp. 1009-1010. Basel: EMH Editores Medicorum Helveticorum

2007

Waser, Beatrice; Eltschinger, Véronique; Linder, Karen; Nunn, Adrian; Reubi, Jean Claude (2007). Selective in vitro targeting of GRP and NMB receptors in human tumours with the new bombesin tracer 177Lu-AMBA. European journal of nuclear medicine and molecular imaging, 34(1), pp. 95-100. Berlin: Springer 10.1007/s00259-006-0229-9

Fleischmann, Achim; Waser, Beatrice; Reubi, Jean Claude (2007). Overexpression of gastrin-releasing peptide receptors in tumor-associated blood vessels of human ovarian neoplasms. Cellular oncology, 29(5), pp. 421-33. Amsterdam: IOS Press

Reubi, Jean Claude (2007). Peptide receptor expression in GEP-NET. Virchows Archiv, 451 Suppl 1, S47-50. Berlin: Springer 10.1007/s00428-007-0443-2

Hayes, Gregory M; Carrigan, Patricia E; Dong, Maoqing; Reubi, Jean-Claude; Miller, Laurence J (2007). A novel secretin receptor splice variant potentially useful for early diagnosis of pancreatic carcinoma. Gastroenterology, 133(3), pp. 853-61. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2007.06.013

Wicki, Andreas; Wild, Damian; Storch, Daniel; Seemayer, Christian; Gotthardt, Martin; Behe, Martin; Kneifel, Stefan; Mihatsch, Michael J; Reubi, Jean-Claude; Mäcke, Helmut R; Christofori, Gerhard (2007). [Lys40(Ahx-DTPA-111In)NH2]-Exendin-4 is a highly efficient radiotherapeutic for glucagon-like peptide-1 receptor-targeted therapy for insulinoma. Clinical cancer research, 13(12), pp. 3696-705. Philadelphia, Pa.: Association for Cancer Research 10.1158/1078-0432.CCR-06-2965

Feytens, Debby; Cescato, Renzo; Reubi, Jean Claude; Tourwé, Dirk (2007). New sst4/5-selective somatostatin peptidomimetics based on a constrained tryptophan scaffold. Journal of medicinal chemistry, 50(14), pp. 3397-401. Easton, Pa.: American Chemical Society 10.1021/jm070246f

Körner, Meike; Stöckli, Martin; Waser, Beatrice; Reubi, Jean Claude (2007). GLP-1 receptor expression in human tumors and human normal tissues: potential for in vivo targeting. Journal of nuclear medicine, 48(5), pp. 736-43. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.106.038679

de Visser, M; Bernard, H F; Erion, J L; Schmidt, M A; Srinivasan, A; Waser, B; Reubi, J C; Krenning, E P; de Jong, M (2007). Novel 111In-labelled bombesin analogues for molecular imaging of prostate tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1228-38. Berlin: Springer 10.1007/s00259-006-0356-3

Zhang, Hanwen; Schuhmacher, Jochen; Waser, Beatrice; Wild, Damian; Eisenhut, Michael; Reubi, Jean Claude; Maecke, Helmut R (2007). DOTA-PESIN, a DOTA-conjugated bombesin derivative designed for the imaging and targeted radionuclide treatment of bombesin receptor-positive tumours. European journal of nuclear medicine and molecular imaging, 34(8), pp. 1198-208. Berlin: Springer 10.1007/s00259-006-0347-4

Antunes, Patricia; Ginj, Mihaela; Walter, Martin A; Chen, Jianhua; Reubi, Jean-Claude; Maecke, Helmut R (2007). Influence of different spacers on the biological profile of a DOTA-somatostatin analogue. Bioconjugate chemistry, 18(1), pp. 84-92. Washington, D.C.: American Chemical Society 10.1021/bc0601673

Antunes, P; Ginj, M; Zhang, H; Waser, B; Baum, R P; Reubi, J C; Maecke, H (2007). Are radiogallium-labelled DOTA-conjugated somatostatin analogues superior to those labelled with other radiometals? European journal of nuclear medicine and molecular imaging, 34(7), pp. 982-93. Berlin: Springer 10.1007/s00259-006-0317-x

Körner, Meike; Reubi, Jean Claude (2007). NPY receptors in human cancer: a review of current knowledge. Peptides, 28(2), pp. 419-25. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.08.037

Melis, M; Forrer, F; Capello, A; Bijster, M; Bernard, B F; Reubi, J C; Krenning, E P; De Jong, M (2007). Up-regulation of somatostatin receptor density on rat CA20948 tumors escaped from low dose [(177)Lu-DOTA(0),Tyr(3)]octreotate therapy. Quarterly journal of nuclear medicine and molecular imaging, 51(4), pp. 324-33. Torino: Minerva Medica

Reubi, Jean Claude (2007). Targeting CCK receptors in human cancers. Current topics in medicinal chemistry, 7(12), pp. 1239-42. Hilversum: Bentham Science Publishers

Fainstein Day, Patricia; Frohman, Lawrence; Garcia Rivello, Hernan; Reubi, Jean Claude; Sevlever, Gustavo; Glerean, Mariela; Fernandez Gianotti, Tomas; Pietrani, Marcelo; Rabadan, Alejandra; Racioppi, Silvina; Bidlingmaier, Martin (2007). Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment. Pituitary, 10(3), pp. 311-9. Norwell, Mass.: Springer Science + Business Media 10.1007/s11102-007-0019-9

Storch, D; Schmitt, JS; Waldherr, C; Waser, B; Reubi, JC; Maecke, HR (2007). Preclinical evaluation of somatostatin analogs bearing two macrocyclic chelators for high specific activity labeling with radiometals. Radiochimica acta, 95(6), pp. 359-69. München: Oldenbourg 10.1524/ract.2007.95.6.359

2006

Körner, Meike; Hayes, Gregory M; Rehmann, Ruth; Zimmermann, Arthur; Scholz, Arne; Wiedenmann, Bertram; Miller, Laurence J; Reubi, Jean Claude (2006). Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma. Journal of hepatology, 45(6), pp. 825-35. Amsterdam: Elsevier 10.1016/j.jhep.2006.06.016

Waser, Beatrice; Rehmann, Ruth; Rivier, Jean; Vale, Wylie; Reubi, Jean Claude (2006). CRF receptors in the rodent and human cardiovascular systems: Species differences. Peptides, 27(12), pp. 3029-38. New York, N.Y.: Elsevier 10.1016/j.peptides.2006.07.005

Cescato, Renzo; Schulz, Stefan; Waser, Beatrice; Eltschinger, Véronique; Rivier, Jean E; Wester, Hans-Jürgen; Culler, Michael; Ginj, Mihaela; Liu, Qisheng; Schonbrunn, Agnes; Reubi, Jean Claude (2006). Internalization of sst2, sst3, and sst5 receptors: effects of somatostatin agonists and antagonists. Journal of nuclear medicine, 47(3), pp. 502-11. New York, N.Y.: Society of Nuclear Medicine

Schmassmann, Adrian; Zoidl, Georg; Peskar, Brigitta M; Waser, Bea; Schmassmann-Suhijar, Diana; Gebbers, Jan-Olaf; Reubi, Jean Claude (2006). Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice. American journal of physiology - gastrointestinal and liver physiology, 290(4), G747-56. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00416.2005

Wild, Damian; Béhé, Martin; Wicki, Andreas; Storch, Daniel; Waser, Beatrice; Gotthardt, Martin; Keil, Boris; Christofori, Gerhard; Reubi, Jean Claude; Mäcke, Helmut R (2006). [Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting. Journal of nuclear medicine, 47(12), pp. 2025-33. New York, N.Y.: Society of Nuclear Medicine

Ginj, Mihaela; Zhang, Hanwen; Waser, Beatrice; Cescato, Renzo; Wild, Damian; Wang, Xuejuan; Erchegyi, Judit; Rivier, Jean; Mäcke, Helmut R; Reubi, Jean Claude (2006). Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 103(44), pp. 16436-41. Washington, D.C.: National Academy of Sciences NAS 10.1073/pnas.0607761103

Ginj, Mihaela; Schmitt, Jörg S; Chen, Jianhua; Waser, Beatrice; Reubi, Jean-Claude; de Jong, Marion; Schulz, Stefan; Maecke, Helmut R (2006). Design, synthesis, and biological evaluation of somatostatin-based radiopeptides. Chemistry & biology, 13(10), pp. 1081-90. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2006.08.012

Lebtahi, Rachida; Moreau, Severine; Marchand-Adam, Sylvain; Debray, Marie-Pierre; Brauner, Michel; Soler, Paul; Marchal, Joëlle; Raguin, Olivier; Gruaz-Guyon, Anne; Reubi, Jean-Claude; Le Guludec, Dominique; Crestani, Bruno (2006). Increased uptake of 111In-octreotide in idiopathic pulmonary fibrosis. Journal of nuclear medicine, 47(8), pp. 1281-7. New York, N.Y.: Society of Nuclear Medicine

Nock, Berthold A; Nikolopoulou, Anastasia; Reubi, Jean-Claude; Maes, Veronique; Conrath, Peter; Tourwé, Dirk; Maina, Theodosia (2006). Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc. Journal of medicinal chemistry, 49(15), pp. 4767-76. Easton, Pa.: American Chemical Society 10.1021/jm060415g

Grace, Christy Rani R; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean; Riek, Roland (2006). Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. Journal of medicinal chemistry, 49(15), pp. 4487-96. Easton, Pa.: American Chemical Society 10.1021/jm060363v

Lantry, Laura E; Cappelletti, Enrico; Maddalena, Mary Ellen; Fox, Jaclyn S; Feng, Weiwei; Chen, Jianqing; Thomas, Regi; Eaton, Stephen M; Bogdan, Nancy J; Arunachalam, Thangavel; Reubi, Jean Claude; Raju, Natarajan; Metcalfe, Edmund C; Lattuada, Luciano; Linder, Karen E; Swenson, Rolf E; Tweedle, Michael F; Nunn, Adrian D (2006). 177Lu-AMBA: Synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer. Journal of nuclear medicine, 47(7), pp. 1144-52. New York, N.Y.: Society of Nuclear Medicine

Kneifel, Stefan; Cordier, Dominik; Good, Stephan; Ionescu, Mihai C S; Ghaffari, Anthony; Hofer, Silvia; Kretzschmar, Martin; Tolnay, Markus; Apostolidis, Christos; Waser, Beatrice; Arnold, Marlene; Mueller-Brand, Jan; Maecke, Helmut R; Reubi, Jean Claude; Merlo, Adrian (2006). Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p. Clinical cancer research, 12(12), pp. 3843-50. Philadelphia, Pa.: Association for Cancer Research 10.1158/1078-0432.CCR-05-2820

Ji, G C; Zhou, S T; Shapiro, G; Reubi, J C; Jurczyk, Simona; Carlton, S M (2006). Analgesic activity of a non-peptide imidazolidinedione somatostatin agonist: in vitro and in vivo studies in rat. Pain, 124(1-2), pp. 34-49. Amsterdam: Elsevier 10.1016/j.pain.2006.03.014

Maina, Theodosia; Nock, Berthold A; Cordopatis, Paul; Bernard, Bert F; Breeman, Wout A P; van Gameren, Arthur; van den Berg, Ria; Reubi, Jean-Claude; Krenning, Eric P; de Jong, Marion (2006). [(99m)Tc]Demotate 2 in the detection of sst(2)-positive tumours: a preclinical comparison with [(111)In]DOTA-tate. European journal of nuclear medicine and molecular imaging, 33(7), pp. 831-40. Berlin: Springer 10.1007/s00259-006-0068-8

Gairí, Margarida; Saiz, Pilar; Madurga, Sergio; Roig, Xavier; Erchegyi, Judit; Koerber, Steven C; Reubi, Jean Claude; Rivier, Jean E; Giralt, Ernest (2006). Conformational analysis of a potent SSTR3-selective somatostatin analogue by NMR in water solution. Journal of Peptide Science, 12(2), pp. 82-91. Chichester: John Wiley & Sons 10.1002/psc.743

Reubi, JC (2006). Radiopeptide targeting for tumor therapy: peptide receptor distribution. In: , (ed.) Radionuclide peptide cancer therapy Chinol M (pp. 31-39). London: Taylor & Francis

Rivier, J; Gulyas, J; Erchegyi, J; Koerber, SC; Grace, C; Riek, R; DiGruccio, M; Perrin, M; Rivier, C; Eltschinger, V; Waser, B; Cescato, R; Reubi, JC; Vale, W (2006). Guiding principles applied in the design of GPCR-selective hypothalamic hormone agonists and antagonists. In: (pp. 117-138). Heidelberg: Springer Verlag 10.1007/3-540-34447-0_8

Gugger, M; Reubi, JC (2006). Somatostatin. In: , (ed.) (pp. 1123-1130). Amsterdam: Elsevier

Koerner, M; Reubi, JC (2006). Somatostatin and NPY. In: , (ed.) (pp. 435-444). Amsterdam: Elsevier

1979

Anderson, B; Reubi, Jean-Claude; Waser, Beatrice (1979). Labor contracts and negotiations. NLN publications(52-1805), pp. 69-74.

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