Reymond, Jean-Louis

Up a level
Export as [feed] RSS
Group by: Date | Item Type | Refereed | No Grouping
Jump to: 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006

2016

Röthlisberger, Pascal; Istrate, Alena; Marcaida Lopez, M. J.; Visini, Ricardo; Stocker, Achim; Reymond, Jean-Louis; Leumann, Christian (2016). X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair. Chemical communications, 52(26), pp. 4749-4752. Royal Society of Chemistry 10.1039/c6cc00374e

Michaud, Gaëlle; Visini, Ricardo; Bergmann, Myriam; Salerno, Gianluca; Bosco, Rosa; Gillon, Emilie; Richichi, Barbara; Nativi, Cristina; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2016). Overcoming antibiotic resistance in Pseudomonas aeruginosa biofilms using glycopeptide dendrimers. Chemical Science, 7(1), pp. 166-182. The Royal Society of Chemistry 10.1039/c5sc03635f

Awale, Mahendra; Reymond, Jean-Louis (2016). Web-based 3D-visualization of the DrugBank chemical space. Journal of Cheminformatics, 8, p. 25. Springer 10.1186/s13321-016-0138-2

Kwok, Albert; Eggimann, Gabriela A.; Heitz, Marc; Reymond, Jean-Louis; Hollfelder, Florian; Darbre, Tamis (2016). Efficient Transfection of siRNA by Peptide Dendrimer-Lipid Conjugates. ChemBioChem, 17(23), pp. 2223-2229. Wiley-VCH 10.1002/cbic.201600485

Tetko, Igor V.; Engkvist, Ola; Koch, Uwe; Reymond, Jean-Louis; Chen, Hongming (2016). BIGCHEM: Challenges and Opportunities for Big Data Analysis in Chemistry. Molecular informatics, 35(11-12), pp. 615-621. Wiley 10.1002/minf.201600073

Bürgi, Justus; Bertrand, Sonia; Marger, Fabrice; Bertrand, Daniel; Reymond, Jean-Louis (2016). Fluorescent Agonists of the α 7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine. Helvetica chimica acta, 99(10), pp. 790-804. Verlag Helvetica Chimica Acta 10.1002/hlca.201600120

Abdel-Sayed, Philippe; Kaeppli, Ariane; Siriwardena, Thissa; Darbre, Tamis; Perron, Karl; Jafari, Paris; Reymond, Jean-Louis; Pioletti, Dominique P.; Applegate, Lee Ann (2016). Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages. Scientific Reports, 6(22020), p. 22020. Nature Publishing Group 10.1038/srep22020

Reymond, Jean-Louis; Visini, Ricardo; Awale, Mahendra (2016). Enumeration of Chemical Fragment Space. In: Erlanson, Daniel A.; Jahnke, Wolfgang (eds.) Fragment-based Drug Discovery Lessons and Outlook. Methods and Principles in Medicinal Chemistry (pp. 57-74). Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA 10.1002/9783527683604.ch03

2015

Pires, João; Siriwardena, Thissa N.; Stach, Michaela; Tinguely, Regula; Kasraian Fard, Sara; Luzzaro, Francesco; Leib, Stephen; Darbre, Tamis; Reymond, Jean-Louis; Endimiani, Andrea (2015). In Vitro Activity of the Novel Antimicrobial Peptide Dendrimer G3KL against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 59(12), pp. 7915-7918. American Society for Microbiology 10.1128/AAC.01853-15

Bergmann, Myriam; Michaud, Gaëlle; Visini, Ricardo; Jin, Xian; Gillon, Emilie; Stocker, Achim; Imberty, Anne; Darbre, Tamis; Reymond, Jean-Louis (2015). Multivalency effects in Pseudomonas aeruginosa biofilm inhibition and dispersal by glycopeptide dendrimers targeting lectin LecA. Organic & biomolecular chemistry, 14(1), pp. 138-148. Royal Society of Chemistry 10.1039/C5OB01682G

Visini, Ricardo; Bergmann, Myriam; Michaud, Gaelle; Pertici, Francesca; Fu, Ou; Pukin, Aliaksei; Branson, Thomas; Thies-Weesie, Dominique; Kemmink, Johan; Gillon, Emilie; Imberty, Anne; Stocker, Achim; Darbre, Tamis; Pieters, Roland; Reymond, Jean-Louis (2015). Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeroginosa lectin LecA. ACS Chemical Biology, 10(11), pp. 2455-2462. American Chemical Society 10.1021/acschembio.5b00302

González Salgado, Amaia; Steinmann, Michael Eduard; Major, Louise L; Sigel, Erwin; Reymond, Jean-Louis; Smith, Terry K; Bütikofer, Peter (2015). Trypanosoma brucei Bloodstream Forms Depend upon Uptake of myo-Inositol for Golgi Complex Phosphatidylinositol Synthesis and Normal Cell Growth. Eukaryotic cell, 14(6), pp. 616-624. American Society for Microbiology ASM 10.1128/EC.00038-15

Giannini, Federico; Bartoloni, Marco; Paul, Lydia E. H.; Süss-Fink, Georg; Reymond, Jean-Louis; Furrer, Julien (2015). Cytotoxic peptide conjugates of dinuclear arene ruthenium trithiolato complexes. Medicinal chemistry communications - MedChemComm, 6(2), pp. 347-350. Royal Society of Chemistry 10.1039/c4md00433g

He, Runze; Reymond, Jean-Louis (2015). Activity and structure studies of antimicrobial cyclic peptides with L,D- architecture linked by a phenyl group (Unpublished). In: SCG Fall Meeting 2015. EPFL Lausanne. 2015.

Jin, Xian; Awale, Mahendra; Zasso, Michaël; Kostro, Daniel; Patiny, Luc; Reymond, Jean-Louis (2015). PDB-Explorer: a web-based interactive map of the protein data bank in shape space. BMC bioinformatics, 16(1), 16:339. BioMed Central 10.1186/s12859-015-0776-9

Simonin, Céline; Awale, Mahendra; Brand, Michael; van Deursen, Ruud; Schwartz, Julian; Fine, Michael; Kovacs, Gergely; Häfliger, Pascal; Gyimesi, Gergely; Sithampari, Abilashan; Charles, Roch-Philippe; Hediger, Matthias; Reymond, Jean-Louis (2015). Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method. Angewandte Chemie (International ed.), 54(49), pp. 14748-14752. Wiley-VCH 10.1002/anie.201507320

Perez, Camilo; Gerber, Sabina; Boilevin, Jérémy; Bucher, Monika; Darbre, Tamis; Aebi, Markus; Reymond, Jean-Louis; Locher, Kaspar P. (2015). Structure and mechanism of an active lipid-linked oligosaccharide flippase. Nature, 524(7566), pp. 433-438. Macmillan Journals Ltd. 10.1038/nature14953

Awale, Mahendra; Reymond, Jean-Louis (2015). Similarity Mapplet: Interactive Visualization of the Directory of Useful Decoys and ChEMBL in High Dimensional Chemical Spaces. Journal of chemical information and modeling, 55(8), pp. 1509-1516. American Chemical Society 10.1021/acs.jcim.5b00182

Bartoloni, Marco; Jin, Xian; Marcaida, Maria José; Banha, João; Di Bonaventura, Ivan; Bongoni, Swathi; Bartho, Kathrin; Gräbner, Olivia; Sefkow, Michael; Darbre, Tamis; Reymond, Jean-Louis (2015). Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability. Chemical Science, 6(10), pp. 5473-5490. The Royal Society of Chemistry 10.1039/C5SC01699A

Reymond, Jean-Louis (2015). Articles of Significant Interest Selected from This Issue by the Editors. Eukaryotic cell, 14(6), p. 527. American Society for Microbiology ASM 10.1128/EC.00075-15

Montalbetti, Nicolas; Simonin, Alexandre; Simonin, Céline; Awale, Mahendra; Reymond, Jean-Louis; Hediger, Matthias (2015). Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2. Biochemical pharmacology, 96(3), pp. 216-224. Elsevier 10.1016/j.bcp.2015.05.002

Reymond, Jean-Louis (2015). The Chemical Space Project. Accounts of chemical research, 48(3), pp. 722-730. American Chemical Society 10.1021/ar500432k

Awale, Mahendra; Jin, Xian; Reymond, Jean-Louis (2015). Stereoselective virtual screening of the ZINC database using atom pair 3D-fingerprints. Journal of Cheminformatics, 7(1), p. 3. Springer 10.1186/s13321-014-0051-5

2014

He, Runze; Reymond, Jean-Louis (11 September 2014). Synergistic folding and potency increase in an antimicrobial peptide pair against Pseudomonas aeruginosa (Unpublished). In: 2014 SCG fall Meeting. Universität Zürich. 11.09.2014.

Naegeli, A.; Michaud, Gaëlle; Schubert, M.; Lin, C.-W.; Lizak, C.; Darbre, Tamis; Reymond, Jean-Louis; Aebi, M. (2014). Substrate Specificity of Cytoplasmic N-Glycosyltransferase. Journal of biological chemistry, 289(35), pp. 24521-24532. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M114.579326

Awale, Mahendra; Reymond, Jean-Louis (2014). Atom Pair 2D-Fingerprints Perceive 3D-Molecular Shape and Pharmacophores for Very Fast Virtual Screening of ZINC and GDB-17. Journal of chemical information and modeling, 54(7), pp. 1892-1907. American Chemical Society 10.1021/ci500232g

Michaud, Gaëlle; Bergmann, Myriam; Salerno, Gianluca; Gillon, Emilie; Imberty, Anne; Richichi, Barbara; Nativi, Cristina; Darbre, Tamis; Reymond, Jean-Louis (June 2014). Synthesis of glycopeptide dendrimers targeting LecA, LecB, or both (Unpublished). In: COST MultiGlycoNano Meeting. Siena, Italy. 25.-28.06.2014.

Ruddigkeit, Lars; Awale, Mahendra; Reymond, Jean-Louis (2014). Expanding the fragrance chemical space for virtual screening. Journal of Cheminformatics, 6(1), p. 27. Springer 10.1186/1758-2946-6-27

Bürgi, Justus; Awale, Mahendra; Boss, Silvan D.; Schaer, Tifany; Marger, Fabrice; Viveros Paredes, Juan Manuel; Bertrand, Sonia; Gertsch, Jürg; Bertrand, Daniel; Reymond, Jean-Louis (2014). Discovery of Potent Positive Allosteric Modulators of the α3β2 Nicotinic Acetylcholine Receptor by a Chemical Space Walk in ChEMBL. ACS chemical neuroscience, 5(5), pp. 346-359. American Chemical Society 10.1021/cn4002297

Awale, Mahendra; Reymond, Jean-Louis (2014). A multi-fingerprint browser for the ZINC database. Nucleic acids research, 42(W1), W234-W239. Information Retrieval Ltd. 10.1093/nar/gku379

Kouri, Tina M.; Awale, Mahendra; Slyby, James K.; Reymond, Jean-Louis; Mehta, Dinesh P. (2014). “Social” Network of Isomers Based on Bond Count Distance: Algorithms. Journal of chemical information and modeling, 54(1), pp. 57-68. American Chemical Society 10.1021/ci4005173

Bartoloni, Marco; Waltersperger, Sandro; Bumann, Mario; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2014). Stereoselective synthesis and structure determination of a bicyclo[3.3.2]decapeptide. Arkivoc, 2014(3), p. 113. Michigan Publishing 10.3998/ark.5550190.p008.500

Lüscher, Benjamin; Clemençon, Benjamin; Marini, Camilla; Huang, Xiao; Sager, Ruth; Jeanneret, Céline; Reymond, Jean-Louis; Albrecht, Christiane; Hediger, Matthias; Surbek, Daniel; Baumann, Marc Ulrich (January 2014). Placental Uric Acid Transport System: Glucose Transporter 9 (SLC2A9). Reproductive sciences, 21(3), 303A-303A. Sage

Hari, Yvonne; Stucki, Silvan R.; Nyakas, Adrien; Blum, Lorenz; Reymond, Jean-Louis; Schürch, Stefan (2014). OMA & OPA – A Software Tool for Mass Spectrometric Sequencing of Nucleic Acids. CHIMIA, 68(1), p. 86. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2013.86

Jeanneret, Céline; Reymond, Jean-Louis (2014). Discovery of TRPV6 inhibitors using ligand based virtual screening (Unpublished). In: International Symposium on Medicinal Chemistry. Lisbon, Portugal. 07.-11.09.2014.

Simonin, Céline; Reymond, Jean-Louis (2014). Discovery of TRPV6 Inhibitors Using Ligand Based Virtual Screening (Unpublished). In: Swiss-Japanese Symposium in Chemical Biology. Berne. 02-03.10.2014.

Stach, Michaela; Siriwardena, Thissa; Köhler, Thilo; van Delden, Christian; Darbre, Tamis; Reymond, Jean-Louis (2014). Combining Topology and Sequence Design for the Discovery of Potent Antimicrobial Peptide Dendrimers against Multidrug-Resistant Pseudomonas aeruginosa. Angewandte Chemie (International ed.), 53(47), pp. 12827-12831. Wiley-VCH 10.1002/anie.201409270

Lizak, C.; Gerber, Sabine; Zinne, D.; Michaud, Gaëlle; Schubert, M.; Chen, F.; Bucherer, Monika; Darbre, Tamis; Zenobi, R.; Reymond, Jean-Louis; Locher, K. P. (2014). A Catalytically Essential Motif in External Loop 5 of the Bacterial Oligosaccharyltransferase PglB. Journal of biological chemistry, 289(2), pp. 735-746. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M113.524751

Eggimann, Gabriela A.; Blattes, Emilyne; Buschor, Stefanie; Biswas, Rasomoy; Kammer, Stephan M.; Darbre, Tamis; Reymond, Jean-Louis (2014). Designed cell penetrating peptide dendrimers efficiently internalize cargo into cells. Chemical communications, 50(55), pp. 7254-7257. Royal Society of Chemistry 10.1039/C4CC02780A

Ruddigkeit, Lars; Reymond, Jean-Louis (2014). The Chemical Space of Flavours. In: Martinez-Mayorga, Karina; Medina-Franco, José Luis (eds.) Foodinformatics - Applications of Chemical Information to Food Chemistry (pp. 83-96). Heidelberg, Germany: Springer 10.1007/978-3-319-10226-9_2

Reymond, Jean-Louis; Ruddigkeit, Lars; Awale, Mahendra (2014). Considerations on the Drug-Like Chemical Space. In: Jacoby, Edgar (ed.) Computational Chemogenomics (pp. 39-64). Singapore: Pan Stanford Publishing

Neier, Reinhard; Reymond, Jean-Louis (2014). A Tribute to Pierre Vogel. Arkivoc, 2014(3), pp. 1-5. Michigan Publishing 10.3998/ark.5550190.0015.301

2013

Bernardi, Anna; Jiménez-Barbero, Jesus; Casnati, Alessandro; De Castro, Cristina; Darbre, Tamis; Fieschi, Franck; Finne, Jukka; Funken, Horst; Jaeger, Karl-Erich; Lahmann, Martina; Lindhorst, Thisbe K.; Marradi, Marco; Messner, Paul; Molinaro, Antonio; Murphy, Paul V.; Nativi, Cristina; Oscarson, Stefan; Penadés, Soledad; Peri, Francesco; Pieters, Roland J.; ... (2013). Multivalent glycoconjugates as anti-pathogenic agents. Chemical Society reviews, 42(11), pp. 4709-4727. Royal Society of Chemistry 10.1039/C2CS35408J

Nyakas, Adrien; Blum, Lorenz C.; Stucki, Silvan R.; Reymond, Jean-Louis; Schürch, Stefan (2013). OMA and OPA—Software-Supported Mass Spectra Analysis of Native and Modified Nucleic Acids. Journal of the American Society for Mass Spectrometry, 24(2), pp. 249-256. Springer 10.1007/s13361-012-0529-1

Awale, Mahendra; van Deursen, Ruud; Reymond, Jean-Louis (2013). MQN-Mapplet: Visualization of Chemical Space with Interactive Maps of DrugBank, ChEMBL, PubChem, GDB-11, and GDB-13. Journal of chemical information and modeling, 53(2), pp. 509-518. American Chemical Society 10.1021/ci300513m

Geotti-Bianchini, Piero; Darbre, Tamis; Reymond, Jean-Louis (2013). pH-tuned metal coordination and peroxidase activity of a peptide dendrimer enzyme model with a Fe(ii)bipyridine at its core. Organic & biomolecular chemistry, 11(2), pp. 344-352. Royal Society of Chemistry 10.1039/c2ob26551f

Kadam, Rameshwar U.; Bergmann, Myriam; Garg, Divita; Gabrieli, Gabriele; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). Structure-Based Optimization of the Terminal Tripeptide in Glycopeptide Dendrimer Inhibitors of Pseudomonas aeruginosa Biofilms Targeting LecA. Chemistry - a European journal, 19(50), pp. 17054-17063. Wiley-VCH 10.1002/chem.201302587

Kadam, Rameshwar U.; Garg, Divita; Schwartz, Julian; Visini, Ricardo; Sattler, Michael; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2013). CH−π “T-Shape” Interaction with Histidine Explains Binding of Aromatic Galactosides to Pseudomonas aeruginosa Lectin LecA. ACS Chemical Biology, 8(9), pp. 1925-1930. American Chemical Society 10.1021/cb400303w

Ravi, Harish Kumar; Stach, Michaela; Soares, Thereza; Darbre, Tamis; Reymond, Jean-Louis; Cascella, Michele (2013). Electrostatics and Flexibility Drive Membrane Recognition and Early Penetration by Antimicrobial Peptide Dendrimer bH1. Chemical communications, 49(78), pp. 8821-8823. Royal Society of Chemistry 10.1039/C3CC44912B

Ruddigkeit, Lars; Blum, Lorenz C.; Reymond, Jean-Louis (2013). Visualization and Virtual Screening of the Chemical Universe Database GDB-17. Journal of chemical information and modeling, 53(1), pp. 56-65. American Chemical Society 10.1021/ci300535x

Reymond, Jean-Louis; Bergmann, Myriam; Darbre, Tamis (2013). Glycopeptide dendrimers as Pseudomonas aeruginosa biofilm inhibitors. Chemical Society reviews, 42(11), pp. 4814-4822. Royal Society of Chemistry 10.1039/c3cs35504g

Gerber, S.; Lizak, C.; Michaud, Gaëlle; Bucher, M.; Darbre, Tamis; Aebi, M.; Reymond, Jean-Louis; Locher, K. P. (2013). Mechanism of bacterial oligosaccharyltransferase: in vitro quantification of sequon binding and catalysis. Journal of biological chemistry, 288(13), pp. 8849-8861. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M112.445940

Heinisch, Tillmann; Langowska, Karolina; Tanner, Pascal; Reymond, Jean-Louis; Meier, Wolfgang; Palivan, Cornelia; Ward, Thomas R. (2013). Fluorescence-Based Assay for the Optimization of the Activity of Artificial Transfer Hydrogenase within a Biocompatible Compartment. ChemCatChem, 5(3), pp. 720-723. WILEY-VCH 10.1002/cctc.201200834

Kwok, Albert; Eggimann, Gabriela; Reymond, Jean-Louis; Darbre, Tamis; Hollfelder, Florian (2013). Peptide Dendrimer/Lipid Hybrid Systems Are Efficient DNA Transfection Reagents: Structure–Activity Relationships Highlight the Role of Charge Distribution Across Dendrimer Generations. ACS nano, 7(5), pp. 4668-4682. American Chemical Society 10.1021/nn400343z

Schwartz, Julian; Awale, Mahendra; Reymond, Jean-Louis (2013). SMIfp (SMILES fingerprint) Chemical Space for Virtual Screening and Visualization of Large Databases of Organic Molecules. Journal of chemical information and modeling, 53(8), pp. 1979-1989. American Chemical Society 10.1021/ci400206h

Eggimann, Gabriela; Buschor, Stefanie; Darbre, Tamis; Reymond, Jean-Louis (2013). Convergent synthesis and cellular uptake of multivalent cell penetrating peptides derived from Tat, Antp, pVEC, TP10 and SAP. Organic & biomolecular chemistry, 11(39), pp. 6717-6733. Royal Society of Chemistry 10.1039/c3ob41023d

Lizak, Christian; Gerber, Sabina; Michaud, Gaëlle; Schubert, Mario; Fan, Yao-Yun; Bucher, Monika; Darbre, Tamis; Aebi, Markus; Reymond, Jean-Louis; Locher, Kaspar P. (2013). Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation. Nature communications, 4(2627), p. 2627. Nature Publishing Group 10.1038/ncomms3627

Reymond, Jean-Louis; Darbre, Tamis (2013). Expanding the Topological Space of Bioactive Peptides. CHIMIA, 67(12), pp. 864-867. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2013.864

2012

Bartoloni, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Synthesis and structure determination of bicyclic bridged peptides. Journal of Peptide Science, 18(S1), S170-S170. John Wiley & Sons

Blattes, E.; Bartoloni, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Biological applications of bicyclic peptides. Journal of Peptide Science, 18(Supplement), S93-S93. John Wiley & Sons 10.1002/psc.2449

Darbre, Tamis; Reymond, Jean-Louis (2012). Dendritic glycopeptides as Pseudomonas aeruginosa biofilm inhibitors. Journal of Peptide Science, 18, S55-S56. Chichester: John Wiley & Sons

Eggimann, G.; Buschor, S.; Darbre, Tamis; Reymond, Jean-Louis (2012). Branched and Dendritic Cell Penetrating Peptides. Journal of Peptide Science, 18, S152-S152. Chichester: John Wiley & Sons

Reymond, Jean-Louis; Darbre, Tamis (2012). Peptide and glycopeptide dendrimer apple trees as enzyme models and for biomedical applications. Organic & biomolecular chemistry, 10(8), pp. 1483-1492. Cambridge: Royal Society of Chemistry 10.1039/c2ob06938e

Stach, M.; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Journal of Peptide Science, 18, S63-S64. John Wiley & Sons

Stach, Michaela; Maillard, Noélie; Kadam, Rameshwar; Kalbermatter, David; Meury, M.; Page, Malcolm; Fotiadis, Dimitrios José; Darbre, Tamis; Reymond, Jean-Louis (2012). Membrane disrupting antimicrobial peptide dendrimers with multiple amino termini. Medicinal chemistry communications - MedChemComm, 3(1), pp. 86-89. Cambridge: Royal Society of Chemistry 10.1039/c1md00272d

Awale, Mahendra; Reymond, Jean-Louis (2012). Cluster analysis of the DrugBank chemical space using molecular quantum numbers. Bioorganic & medicinal chemistry, 20(18), pp. 5372-5378. Amsterdam: Elsevier 10.1016/j.bmc.2012.03.017

Bréthous, Lise; Garcia-Delgado, Noemi; Schwartz, Julian; Bertrand, Sonia; Bertrand, Daniel; Reymond, Jean-Louis (2012). Synthesis and Nicotinic Receptor Activity of Chemical Space Analogues of N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-Diazabicyclo[3.2.2]nonane-4-carboxylic Acid 4-Bromophenyl Ester (SSR180711). Journal of medicinal chemistry, 55(10), pp. 4605-4618. Easton, Pa.: American Chemical Society 10.1021/jm300030r

Reymond, Jean-Louis; Awale, Mahendra (2012). Exploring Chemical Space for Drug Discovery Using the Chemical Universe Database. ACS chemical neuroscience, 3(9), pp. 649-657. Washington, D.C.: American Chemical Society 10.1021/cn3000422

Reymond, Jean-Louis; Ruddigkeit, Lars; Blum, Lorenz; van Deursen, Ruud (2012). The enumeration of chemical space. Wiley interdisciplinary reviews WIREs - computational molecular science, 2(5), pp. 717-733. Hoboken, N.J.: Wiley-Blackwell 10.1002/wcms.1104

Ruddigkeit, Lars; van Deursen, Ruud; C.Blum, Lorenz; Reymond, Jean-Louis (2012). Enumeration of 166 Billion Organic Small Molecules in the Chemical Universe Database GDB-17. Journal of chemical information and modeling, 52(11), pp. 2864-2875. Washington, D.C.: American Chemical Society 10.1021/ci300415d

Reymond, Jean-Louis (2012). Screening Methods for Enzymes. In: Carreira, Eric M.; Yamamoto, Hisashi (eds.) Comprehensive Chirality. Volume 7: Synthetic Methods VI - Enzymatic and Semi-Enzymatic (pp. 6-20). Amsterdam: Elsevier 10.1016/B978-0-08-095167-6.00702-3

Jeanneret, C.; Reymond, Jean-Louis (2012). Discovery of NHA2 Inhibitors Using Ligand Based Virtual Screening. In: NCCR TransCure Site Visit. Bern. 15.-16.10.2012.

Jeanneret, C.; Reymond, J.-L. (2012). Ligand Based Discovery of TRPV6 Inhibitors. In: NCCR TransCure Site Visit. Bern. 15.-16.10.2012.

Jeanneret, C.; Reymond, Jean-Louis (2012). Development of New TRPV6 Inhibitors. In: Präsentation anlässlich des NCCR TransCure Annual Retreat. Gruyère. 30.05.-01.06.2012.

2011

Bartoloni, Marco; Kadam, Rameshwar U.; Schwartz, Julian; Furrer, Julien; Darbre, Tamis; Reymond, Jean-Louis (2011). Expanding the accessible chemical space by solid phase synthesis of bicyclic homodetic peptides. Chemical communications, 47(47), p. 12634. Cambridge: Royal Society of Chemistry 10.1039/c1cc15704c

Reymond, Jean-Louis; Darbre, Tamis (2011). Combinatorial Libraries of Dendritic Glycoclusters. In: Renaudet, O.; Spinelli, N. (eds.) Synthesis and Biological Applications of Glycoconjugates (pp. 116-128). Bentham Science Publishers

Kadam, Rameshwar U.; Bergmann, Myriam; Hurley, Matthew; Garg, Divita; Cacciarini, Martina; Swiderska, Magdalena A.; Nativi, Cristina; Sattler, Michael; Smyth, Alan R.; Williams, Paul; Camara, Miguel; Stocker, Achim; Darbre, Tamis; Reymond, Jean-Louis (2011). A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms. Angewandte Chemie (International ed.), 50(45), pp. 10631-10635. Weinheim: Wiley-VCH 10.1002/anie.201104342

Johansson, Emma M.V.; Kadam, Rameshwar U.; Rispoli, Gabriele; Crusz, Shanika A.; Bartels, Kai-Malte; Diggle, Stephen P.; Camara, Miguel; Williams, Paul; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2011). Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids. Medicinal chemistry communications - MedChemComm, 2(5), pp. 418-420. Cambridge: Royal Society of Chemistry 10.1039/c0md00270d

Blum, Lorenz C.; van Deursen, Ruud; Bertrand, Sonia; Mayer, Milena; Buergi, Justus J.; Bertrand, Daniel; Reymond, Jean-Louis (2011). Discovery of alpha 7-Nicotinic Receptor Ligands by Virtual Screening of the Chemical Universe Database GDB-13. Journal of chemical information and modeling, 51(12), pp. 3105-3112. Washington, D.C.: American Chemical Society 10.1021/ci200410u

Blum, Lorenz C.; van Deursen, Ruud; Reymond, Jean-Louis (2011). Visualisation and subsets of the chemical universe database GDB-13 for virtual screening. Journal of computer-aided molecular design, 25(7), pp. 637-647. Dordrecht: Springer 10.1007/s10822-011-9436-y

Botelho, Tiago O.; Guevara, Tibisay; Marrero, Aniebrys; Arede, Pedro; Fluxa, Viviana S.; Reymond, Jean-Louis; Oliveira, Duarte C.; Xavier Gomis-Rueth, F. (2011). Structural and Functional Analyses Reveal That Staphylococcus aureus Antibiotic Resistance Factor HmrA Is a Zinc-dependent Endopeptidase. Journal of biological chemistry, 286(29), pp. 25697-25709. Bethesda, Md.: American Society for Biochemistry and Molecular Biology 10.1074/jbc.M111.247437

Darbre, T.; Reymond, Jean-Louis (2011). Peptide Dendrimers as Artificial Proteins. In: Campagna, S.; Ceroni, P.; Puntoriero, F. (eds.) Designing Dendrimers (pp. 505-528). Chichester: John Wiley & Sons

Euzen, Ronan; Reymond, Jean-Louis (2011). Glycopeptide dendrimers: tuning carbohydrate-lectin interactions with amino acids. Molecular bioSystems, 7(2), pp. 411-421. Cambridge: Royal Society of Chemistry 10.1039/c0mb00177e

Euzen, Ronan; Reymond, Jean-Louis (2011). Synthesis of glycopeptide dendrimers, dimerization and affinity for Concanavalin A. Bioorganic & medicinal chemistry, 19(9), pp. 2879-2887. Amsterdam: Elsevier 10.1016/j.bmc.2011.03.047

Fluxa, Viviana S.; Maillard, Noelie; Page, Malcolm G.P.; Reymond, Jean-Louis (2011). Bead diffusion assay for discovering antimicrobial cyclic peptides. Chemical communications, 47(5), pp. 1434-1436. Cambridge: Royal Society of Chemistry 10.1039/c0cc04670a

Maillard, Noelie; Babiak, Peter; Syed, Salahuddin; Biswas, Rasomoy; Mandrich, Luigi; Manco, Giuseppe; Reymond, Jean-Louis (2011). Five-Substrate Cocktail as a Sensor Array for Measuring Enzyme Activity Fingerprints of Lipases and Esterases. Analytical chemistry, 83(4), pp. 1437-1442. Washington, D.C.: American Chemical Society 10.1021/ac102994n

Reymond, Jean-Louis; van Deursen, Ruud; Bertrand, D. (2011). What we have learned from crystal structures of proteins to receptor function. Biochemical pharmacology, 82(11), pp. 1521-1527. New York, N.Y.: Elsevier 10.1016/j.bcp.2011.07.061

Reymond, Jean-Louis; Blum, Lorenz C.; van Deursen, Ruud (2011). Exploring the Chemical Space of Known and Unknown Organic Small Molecules at www.gdb.unibe.ch. CHIMIA, 65(11), pp. 863-867. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2011.863

van Deursen, Ruud; Blum, Lorenz C.; Reymond, Jean-Louis (2011). Visualisation of the chemical space of fragments, lead-like and drug-like molecules in PubChem. Journal of computer-aided molecular design, 25(7), pp. 649-662. Dordrecht: Springer 10.1007/s10822-011-9437-x

Maillard, N.; Biswas, Rasomoy; Darbre, Tamis; Reymond, Jean-Louis (2011). Combinatorial Discovery of Peptide Dendrimer Enzyme Models Hydrolyzing Isobutyryl Fluorescein. ACS combinatorial science, 13(3), pp. 310-320. Washington, D.C.: American Chemical Society 10.1021/co200006z

Uhlich, N.A.; Darbre, Tamis; Reymond, Jean-Louis (2011). Peptide dendrimer enzyme models for ester hydrolysis and aldolizationprepared by convergent thioether ligation. Organic & biomolecular chemistry, 9(20), pp. 7071-7084. Cambridge: Royal Society of Chemistry 10.1039/c1ob05877k

2010

Luethi, Erika; Nguyen, Kong T; Bürzle, Marc; Blum, Lorenz C; Suzuki, Yoshiro; Hediger, Matthias; Reymond, Jean-Louis (2010). Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). Journal of medicinal chemistry, 53(19), pp. 7236-50. Easton, Pa.: American Chemical Society 10.1021/jm100959g

Johansson, Emma M.V.; Dubois, Joëlle; Darbre, Tamis; Reymond, Jean-Louis (2010). Glycopeptide dendrimer colchicine conjugates targeting cancer cells. Bioorganic & medicinal chemistry, 18(17), pp. 6589-6597. Amsterdam: Elsevier 10.1016/j.bmc.2010.04.026

Uhlich, Nicolas A.; Natalello, Antonino; Kadam, Rameshwar U.; Doglia, Silvia M.; Reymond, Jean-Louis; Darbre, Tamis (2010). Structure and Binding of Peptide-Dendrimer Ligands to Vitamin B12. ChemBioChem, 11(3), pp. 358-365. Weinheim: Wiley-VCH 10.1002/cbic.200900657

van Dursen, Ruud; Blum, Lorenz C.; Reymond, Jean-Louis (2010). A Searchable Map of Pubchem. Journal of chemical information and modeling, 50(11), pp. 1924-1934. Washington, D.C.: American Chemical Society 10.1021/ci100237q

Biswas, Rasomoy; Maillard, Noélie; Kofoed, Jacob; Reymond, Jean-Louis (2010). Comparing dendritic with linear esterase peptides by screening SPOT arrays for catalysis. Chemical communications, 46(46), p. 8746. Cambridge: Royal Society of Chemistry 10.1039/c0cc02700f

Garcia-Delgado, Noemi; Bertrand, Sonia; Nguyen, Kong T.; van Deursen, Ruud; Bertrand, Daniel; Reymond, Jean-Louis (2010). Exploring a7-Nicotinic Receptor Ligand Diversity by Scaffold Enumeration from the Chemical Universe Database GDB. ACS medicinal chemistry letters, 1(8), pp. 422-426. Washington, D.C.: American Chemical Society 10.1021/ml100125f

Reymond, Jean-Louis (2010). Selected papers from the Biotrans 2009 Conference. Journal of molecular catalysis. B - enzymatic, 65(1-4), pp. 1-2. Amsterdam: Elsevier 10.1016/j.molcatb.2010.05.006

Reymond, Jean-Louis; Sheldon, Roger A. (2010). Future turnovers in enzyme catalysis. Current opinion in chemical biology, 14(2), pp. 113-114. Amsterdam: Elsevier 10.1016/j.cbpa.2010.02.019

Reymond, Jean-Louis; van Deursen, Ruud; Blum, Lorenz C.; Ruddigkeit, Lars (2010). Chemical space as a source for new drugs. Medicinal chemistry communications - MedChemComm, 1(1), p. 30. Cambridge: Royal Society of Chemistry 10.1039/c0md00020e

2009

Uhlich, Nicolas A.; Sommer, Peter; Bühr, Claudia; Schürch, Stefan; Reymond, Jean-Louis; Darbre, Tamis (2009). Remote Control of Bipyridine-Metal Coordination within a Peptide Dendrimer. Chemical communications(41), p. 6237. Cambridge: Royal Society of Chemistry 10.1039/b912291e

Javor, Sacha; Reymond, Jean-Louis (2009). Structure Activity Relationship Studies in Single-Site-Esterase Peptide Dendrimers. Israel journal of chemistry, 49(1), pp. 129-136. Weinheim: Wiley-VCH 10.1560/IJC.49.1.129

Blum, Lorenz C.; Reymond, Jean-Louis (2009). 970 Million Drug-like Small Molecules for Virtual Screening in the Chemical Universe Database GDB-13 (Communication). Journal of the American Chemical Society, 131(25), pp. 8732-8733. Washington, D.C.: American Chemical Society 10.1021/ja902302h

Sommer, Peter; Fluxa, Viviana S.; Darbre, Tamis; Reymond, Jean-Louis (2009). Proteolysis of Peptide Dendrimers. ChemBioChem, 10(9), pp. 1527-1536. Weinheim: Wiley-VCH 10.1002/cbic.200900060

Dolphin, Gunnar T.; Renaudet, Olivier; Ouberai, Myriam; Dumy, Pascal; Garcia, Julian; Reymond, Jean-Louis (2009). Phenolic oxime oligomers inhibit Alzheimer's amyloid fibril formation and disaggregate fibrils in vitro. ChemBioChem, 10(8), pp. 1325-1329. Weinheim: Wiley-VCH 10.1002/cbic.200900044

Maillard, Noélie; Darbre, Tamis; Reymond, Jean-Louis (2009). Identification of Catalytic Peptide Dendrimers by "Off-Bead" in Silica High-Throughput Screening of Combinatorial Libraries. Journal of combinatorial chemistry, 11(4), pp. 667-675. Washington, D.C.: American Chemical Society 10.1021/cc9000289

Nguyen, Kong Thong; Luethi, Erika; Syed, Salahuddin; Urwyler, Stephan; Bertrand, Sonia; Berrand, Daniel; Reymond, Jean-Louis (2009). 3-(Aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB. Bioorganic and medicinal chemistry letters, 19(14), pp. 3832-3835. New York, N.Y.: Pergamon 10.1016/j.bmcl.2009.04.021

Javor, Sacha; Reymond, Jean-Louis (2009). Molecular dynamics and docking studies of single site esterase peptide dendrimers. Journal of organic chemistry, 74(10), pp. 3665-3674. Washington, D.C.: American Chemical Society 10.1021/jo802743c

Reymond, Jean-Louis; Nguyen, Kong Thong (2009). Exploration of Chemical Space for Drug Discovery by Database Generation. Chimica oggi / Chemistry today, 27(2), pp. 37-40. Milano: TeknoScienze

Kolomiets, Elena; Swiderska, Magdalena A.; Kadam, Rameshwar U.; Johansson, Emma M.V.; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2009). Glycopeptide dendrimers with high affinity for the fucose binding lectin PA-IIL from Pseudomonas aeruginosa. ChemMedChem, 4(4), pp. 562-569. Weinheim: Wiley-VCH 10.1002/cmdc.200800380

Maillard, Noélie; Clouet, Anthony; Darbre, Tamis; Reymond, Jean-Louis (2009). Combinatorial Libraries of Peptide Dendrimers: Design, Synthesis, On-Bead High-Throughput Screening, Bead Decoding and Characterization. Nature protocols, 4(2), pp. 132-142. London: Nature Publishing Group 10.1038/nprot.2008.241

Reymond, Jean-Louis; Fluxa, Viviana S.; Maillard, Noélie (2009). Enzyme Assays. Chemical communications(1), pp. 34-46. Cambridge: Royal Society of Chemistry 10.1039/b813732c

Fluxa, Viviana S.; Reymond, Jean-Louis (2009). On-bed cyclization in a combinatorial library of 15.625 octapeptides. Bioorganic & medicinal chemistry, 17(3), pp. 1018-1025. Amsterdam: Elsevier 10.1016/j.bmc.2008.01.045

Reymond, Jean-Louis (2009). Exploration of Chemical Space for Drug Discovery by Database Generation. ABC Technologies Meeting, Basel, January 22, 2009.

Reymond, Jean-Louis (2009). Chemical Space Dimensions. COST Angiokem WG Meeting, Prague, April 3, 2009.

Reymond, Jean-Louis (2009). Glycopeptide Dendrimers and RAFTs as Antibacterial Agents. COST D34 Meeting, Edinburgh, May 8, 2009.

Reymond, Jean-Louis (2009). What is contained in Chemical Space? Gordon Conference on CADD, Tilton School, NH, July 22, 2009.

Reymond, Jean-Louis (2009). Exploration of Chemical Space for Drug Discovery by Database Generation. Swiss-Japanese Biomolecular Chemistry Symposium, September 11-12, 2009.

Reymond, Jean-Louis (2009). The Cemical Universe Database GDB and its Use for Drug Discovery. Max Planck Institut, Dortmund, September 16, 2009.

Reymond, Jean-Louis (2009). Exploration of Chemical Space for Drug Discovery by Database Generation. Nature Chemical Biology Symposium, Boston, September 20, 2009.

Reymond, Jean-Louis (2009). Substrate Arrays for Fluorescence-Based Enzyme Fingerprinting and High-Throughput Screening. Biotecnet, Olten, November 18, 2009.

Reymond, Jean-Louis (2009). Sprachliche Generierung neuer Moleküle. Collegium Generale, Universität Bern, November 18, 2009.

Reymond, Jean-Louis (2009). Exploration of Chemical Space for Drug Discovery by Database Generation. Glaxo-Smithkline, London, December 3, 2009.

Reymond, Jean-Louis (2009). Exploring Chemical Space with DCB. European Bioinformatics Institute, Cambridge, U.K., December 4, 2009.

2008

Reymond, Jean-Louis (2008). Colorimetric and Fluorescence-Based Screening. In: Lutz, Stefan; Bornscheuner, Uwe Theo (eds.) Protein Engineering Handbook (pp. 669-711). Weinheim: Wiley-VCH

Reymond, Jean-Louis; Streit, W. (2008). The Search for New Enzymes. In: Gotor, Vincente; Alfonso, Ignacio; Garcia-Uridales, Eduardo (eds.) Asymmetric Organic Synthesis with Enzymes (pp. 65-86). Weinheim: Wiley-VCH

Reymond, Jean-Louis (2008). Fluorescence Assays for Biotransformations. In: Fessner, Wolf-Dieter; Anthonsen, Thorleif (eds.) Modern Biocatalysis (pp. 1-16). Weinheim: Wiley-VCH

Javor, Sacha; Natalello, Antonino; Doglia, Silvia Maria; Reymond, Jean-Louis (2008). a-Helix Stabilization within a Peptide Dendrimer [Communication]. Journal of the American Chemical Society, 130(51), pp. 17248-17249. Washington, D.C.: American Chemical Society 10.1021/ja8076236

Johansson, Emma M.V.; Crusz, Shanika A.; Kolomiets, Elena; Buts, Lieven; Kadam, Rameshwar U.; Cacciarini, Martina; Bartels, Kai-Malte; Diggle, Stephen P.; Cámara, Miguel; Williams, Paul; Loris, Remy; Nativi, Cristina; Rosenau, Frank; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2008). Inhibition and Dispersion of Pseudomonas aeruginosa Biofilms by Glycopeptide Dendrimers Targeting the Fucose-Specific Lectin LecB. Chemistry & biology, 15(12), pp. 1249-1257. San Francisco, Calif.: Current Biology Ltd. 10.1016/j.chembiol.2008.10.009

Duléry, Vincent; Uhlich, Nicolas A.; Maillard, Noélie; Fluxa, Viviana S.; Garcia, Julian; Dumy, Pascal; Renaudet, Olivier; Reymond, Jean-Louis; Darbre, Tamis (2008). A cyclodecapeptide ligand to vitamin B12. Organic & biomolecular chemistry, 6(22), pp. 4134-4141. Cambridge: Royal Society of Chemistry 10.1039/b811234g

Darbre, Tamis; Reymond, Jean-Louis (2008). Glycopeptide dendrimers for biomedical applications. Current topics in medicinal chemistry, 8(14), pp. 1286-1293. Hilversum: Bentham Science Publishers 10.2174/156802608785849058

Nguyen, Kong Thong; Syed, Salahuddin; Urwyler, Stephan; Bertrand, Sonia; Bertrand, Daniel; Reymond, Jean-Louis (2008). Discovery of NMDA Glycine Site Inhibitors from the Chemical Universe Database GDB. ChemMedChem, 3(10), pp. 1520-1524. Weinheim: Wiley-VCH 10.1002/cmdc.200800198

Fluxa, Viviana S.; Wahler, Denis; Reymond, Jean-Louis (2008). Enzyme assay and activity fingerprinting of hydrolases with red-chromogenic adrenaline test. Nature protocols, 3(8), pp. 1270-1277. London: Nature Publishing Group 10.1038/nprot.2008.106

Sommer, Peter; Uhlich, Nicolas; Reymond, Jean-Louis; Darbre, Tamis (2008). A Peptide Dendrimer Model for Vitamin B(12). ChemBioChem, 9(5), pp. 689-693. Weinheim: Wiley-VCH 10.1002/cbic.200700606

Reymond, Jean-Louis (2008). Substrate Arrays for Fluorescence-Based Enzyme Fingerpringing and High-Throughput Screening. Annals of the New York Academy of Sciences, 1130(1), pp. 12-20. Boston, Mass.: Blackwell 10.1196/annals.1430.000

Swiderska, Magdalena; Reymond, Jean-Louis (2008). A dendritic signal amplifier (commentary). Nature chemistry, 1(7), pp. 527-528. London: Nature Publishing Group 10.1038/nchem.385

Nguyen, Kong Thong; Blum, Lorenz C.; van Deursen, Ruud; Reymond, Jean-Louis (2008). Classification of Organic Molecules by Molecular Quantum Numbers (Communication). ChemMedChem, 4(11), pp. 1803-1805. Weinheim: Wiley-VCH 10.1002/cmdc.200900317

Reymond, Jean-Louis (2008). Substrate Arrays for Fluorescence-based Enzyme Fingerprinting and High-Throughput Screening, University of Bicocca, Milano, January 28, 2008.

Reymond, Jean-Louis (2008). Substrate Arrays for Fluorescence-based Enzyme Fingerprinting and High-Throughput Screening, Polytecnica Milano, January 29, 2008.

Reymond, Jean-Louis (2008). A Chemical Information Strategy to Define New Synthetic Targets. COST ACTION ANGIOKEM, CM0602. Workshop of working groups 3 and 4. Certosa di Pontignano, Siena, February 15-16, 2008.

Reymond, Jean-Louis (2008). Artifical Proteins and Glycoproteins with Peptide Dendrimers. Société Française de Chimie. Journée commune SFC-DCO/SCT/ANP. Ecole Nationale Supérieure de Chimie de Paris.March 11, 2008.

Reymond, Jean-Louis (2008). Methods for Enzyme High-Throughput Screening and Fingerprinting. Workshop on Directed Evolution. Jülich Forschungszentrum, Jülich. March 12, 2008.

Reymond, Jean-Louis (2008). Metal Coordinating Peptide Dendrimers. IBAAC final meeeting, Ecole de Chimie Paris. March 17-18, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. University of Southern Florida, Tampa, April 3, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. American Chemical Society Meeting Spring 2008, New Orleans, communication no 74 (Thomas Kuhn Paradigm Shift Award Competition). April 7, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. Pfizer Research Center, Groton, CT. April 8, 2008.

Reymond, Jean-Louis (2008). Practical Methods for Enzyme High-Throughput Screening and Fingerprinting. CBSO Bussang, France. June 3, 2008.

Reymond, Jean-Louis (2008). The Search for Artificial Enzymes: from Antibodies to Dendrimers. Trends in Enzymology, St.-Malo, France. July 3, 2008.

Reymond, Jean-Louis (2008). Two Stories of Inhibitors from Libraries: Biofilms and Neurochemicals. Columbia University, New York, July 14, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. EFMS-ISMC Meeting, Vienna. September 3, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. University of New Mexico. November 3, 2008.

Reymond, Jean-Louis (2008). Peptide Dendrimers as Protein Enzymes and Glycoproteins. University of Minnesota. November 11, 2008.

Reymond, Jean-Louis (2008). Exploration of Chemical Space for Drug Discovery by Database Generation. University of California, San Francisco. November 20, 2008.

Reymond, Jean-Louis (2008). Designing screens and screening designs: from catalytic antibodies to peptide dendimer enzyme models. University of Cambridge, UK. December 8, 2008.

2007

Kofoed, Jacob; Reymond, Jean-Louis (2007). Identification of protease substrates by combinatorial profiling on tentagel bead. Chemical communications, 43, pp. 4453-4455. Cambridge: Royal Society of Chemistry 10.1039/b713595e

Kofoed, Jacob; Reymond, Jean-Louis (2007). A General Method for Designing Combinatorial Peptide Libraries Decodable by Amino Acid Analysis. Journal of combinatorial chemistry, 9(6), pp. 1046-1052. Washington, D.C.: American Chemical Society 10.1021/cc7001155

Javor, Sacha; Delort, Estelle; Darbre, Tamis; Reymond, Jean-Louis (2007). A Peptide Dendrimer Enzyme Model with a Single Catalytic Site at the Core. Journal of the American Chemical Society, 129(43), pp. 13238-13246. Washington, D.C.: American Chemical Society 10.1021/ja074115f

Delort, Estelle; Szöcs, Edit; Widmer, Roland; Siegenthaler, Hans; Reymond, Jean-Louis (2007). STM-Visualization of Thiol-Containing Peptide Dendrimers on Au(111). Macromolecular bioscience, 7(8), pp. 1024-1031. Weinheim: Wiley-VCH 10.1002/mabi.200700036

Johansson, Emma; Kolomiets, Elena; Rosenau, Frank; Jaeger, Karl-Erich; Darbre, Tamis; Reymond, Jean-Louis (2007). Combinatorial Variation of Branching Length and Multivalency in a Large (390,625 Member) Glycopeptide Dendrimer Library: Ligands for Fucose-specific Lectins. New journal of chemistry, 31(7), pp. 1291-1299. London: Royal Society of Chemistry 10.1039/b616051b

Kolomiets, Elena; Johansson, Emma; Renaudet, Olivier; Darbre, Tamis; Reymond, Jean-Louis (2007). Neoglycopeptide Dendrimer Libraries as a Source of Lectin Binding Ligands. Organic letters, 9(8), pp. 1465-1468. Washington, D.C.: American Chemical Society 10.1021/ol070119d

van Deursen, Ruud; Reymond, Jean-Louis (2007). Chemical Space Travel. ChemMedChem, 2(5), pp. 636-640. Weinheim: Wiley-VCH 10.1002/cmdc.200700021

Fink, Tobias; Reymond, Jean-Louis (2007). Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physico-chemical properties, compound classes and drug discovery. Journal of chemical information and modeling, 47(2), pp. 342-353. Washington, D.C.: American Chemical Society 10.1021/ci600423u

Sicart, Renaud; Collin, Marie-Pierre; Reymond, Jean-Louis (2007). Fluorogenic Substrates for Lipases, Esterases and Acylases Using a TIM-Mechanism for Signal Release. Biotechnology journal, 2(2), pp. 221-231. Weinheim: Wiley 10.1002/biot.200600181

Reymond, Jean-Louis; Babiak, Peter (2007). Screening Systems. In: Ulber, Roland; Sell, Dieter (eds.) White Biotechnology. Advances in Biochemical Engineering/Biotechnology: Vol. 105 (pp. 31-58). Heidelberg: Springer Verlag 10.1007/10_2006_032

Darbre, Tamis; Reymond, Jean-Louis (2007). A Peptide Dendrimer Approach to Artificial Enzymes. Chimica oggi / Chemistry today, 25, pp. 25-27. Milano: TeknoScienze

Tallant, Cynthia; García-Castellanos, Raquel; Marrero, Aniebrys; Canals, Francesc; Yang, Yongzheng; Reymond, Jean-Louis; Solà, Maria; Baumann, Ulrich; Gomis-Rüth, F. Xavier (2007). Activity of ulilysin, an archaeal PAPP-A-related gelatinase and IGFBP proteas. Biological chemistry, 388(1), pp. 1243-1253. Berlin: De Gruyter 10.1515/BC.2007.143

2006

Darbre, Tamis; Reymond, Jean-Louis (2006). Peptide Dendrimers as Artificial Enzymes, Receptors, and Drug-Delivery Agents. Accounts of chemical research, 39(12), pp. 925-934. Easton, Pa.: American Chemical Society 10.1021/ar050203y

Kofoed, Jacob; Darbre, Tamis; Reymond, Jean-Louis (2006). Artificial aldolases from peptide dendrimer combinatorial libraries. Organic & biomolecular chemistry, 4(17), pp. 3268-3281. Cambridge: Royal Society of Chemistry 10.1039/b607342e

Grognux, Johann; Reymond, Jean-Louis (2006). A red-fluorescent substrate microarray for lipase fingerprinting. Molecular bioSystems, 2(10), pp. 492-498. Cambridge: Royal Society of Chemistry 10.1039/b609275f

Delort, Estelle; Nguyen-Trung, Nhat-Quang; Darbre, Tamis; Reymond, Jean-Louis (2006). Synthesis and Activity of Histidine Containing Catalytic Peptide Dendrimers. Journal of organic chemistry, 71(12), pp. 4468-4480. Washington, D.C.: American Chemical Society 10.1021/jo060273y

Elend, C; Schmeisser, C; Leggewie, C; Babiak, Peter; Carballeira, José Daniel; Steele, H; Reymond, Jean-Louis; Jaeger, Karl-Erich; Streit, Wolfgang (2006). Isolation and biochemical characterization of two novel metagenome-derived esterases. Applied and environmental microbiology, 72(5), pp. 3637-3645. Washington, D.C.: American Society for Microbiology 10.1128/AEM.72.5.3637-3645.2006

Yang, Yongzheng; Babiak, Peter; Reymond, Jean-Louis (2006). Low background FRET- substrates for lipases and esterases suitable for high-throughput screening under basic (pH 11) conditions. Organic & biomolecular chemistry, 4(9), pp. 1746-1754. Cambridge: Royal Society of Chemistry 10.1039/b601151a

Kofoed, Jacob; Darbre, Tamis; Reymond, Jean-Louis (2006). Dual Mechanism of Zinc-Proline Catalyzed Aldol Reactions in Water. Chemical communications, 14(14), p. 1482. Cambridge: Royal Society of Chemistry 10.1039/b600703a

Yang, Yongzheng; Babiak, Peter; Reymond, Jean-Louis (2006). New Monofunctionalized Fluorescein Derivatives for the Efficient High-Throughput Screening of Lipases and Esterases in Aqueous Media. Helvetica chimica acta, 89(3), pp. 404-415. Basel: Verlag Helvetica Chimica Acta 10.1002/hlca.200690041

Clouet, Anthony; Darbre, Tamis; Reymond, Jean-Louis (2006). Combinatorial Synthesis, Selection and Properties of Esterase Peptide Dendrimers. Biopolymers, 84(1), pp. 114-123. Hoboken, N.J.: John Wiley & Sons, Inc. 10.1002/bip.20394

Reymond, Jean-Louis (2006). Fingerprinting Methods for Hydrolases. In: Reymond, Jean-Louis (ed.) Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting (pp. 271-302). Weinheim: Wiley-VCH

Reymond, Jean-Louis (ed.) (2006). Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting 15. Weinheim: Wiley-VCH 10.1016/j.copbio.2004.06.008

Provide Feedback