Ucurum Fotiadis, Zöhre

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2024

Harder, Daniel; Ritzmann, Noah; Ucurum Fotiadis, Zöhre; Müller, Daniel J; Fotiadis, Dimitrios (2024). Light Color-Controlled pH-Adjustment of Aqueous Solutions Using Engineered Proteoliposomes. (In Press). Advanced science(e2307524), e2307524. Wiley 10.1002/advs.202307524

2023

Ayoub, Nooraldeen; Roth, Patrick; Ucurum, Zöhre; Fotiadis, Dimitrios; Hirschi, Stephan (2023). Structural and biochemical insights into His-tag-induced higher-order oligomerization of membrane proteins by cryo-EM and size exclusion chromatography. Journal of structural biology, 215(1), p. 107924. Elsevier 10.1016/j.jsb.2022.107924

2022

Stauffer, Mirko; Jeckelmann, Jean-Marc; Ilgü, Hüseyin; Ucurum, Zöhre; Boggavarapu, Rajendra; Fotiadis, Dimitrios (2022). Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Communications chemistry, 5(1) Springer Nature 10.1038/s42004-022-00636-0

2021

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). High-resolution structure of the amino acid transporter AdiC reveals insights into the role of water molecules and networks in oligomerization and substrate binding. BMC biology, 19(1), p. 179. BioMed Central 10.1186/s12915-021-01102-4

Stauffer, Mirko; Ucurum, Zöhre; Harder, Daniel; Fotiadis, Dimitrios (2021). Engineering and functional characterization of a proton-driven β-lactam antibiotic translocation module for bionanotechnological applications. Scientific reports, 11(1), p. 17205. Springer Nature 10.1038/s41598-021-96298-4

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Lemmin, Thomas; Fotiadis, Dimitrios (2021). Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin. Nature communications, 12(1), p. 4107. Nature Publishing Group 10.1038/s41467-021-24429-6

2020

Kantipudi, Satish; Jeckelmann, Jean-Marc; Ucurum, Zöhre; Bosshart, Patrick D.; Fotiadis, Dimitrios (2020). The Heavy Chain 4F2hc Modulates the Substrate Affinity and Specificity of the Light Chains LAT1 and LAT2. International journal of molecular sciences, 21(20) MDPI 10.3390/ijms21207573

Stauffer, Mirko; Hirschi, Stephan; Ucurum, Zöhre; Harder, Daniel; Schlesinger, Ramona; Fotiadis, Dimitrios (2020). Engineering and Production of the Light-Driven Proton Pump Bacteriorhodopsin in 2D Crystals for Basic Research and Applied Technologies. Methods and protocols, 3(3) MDPI AG 10.3390/mps3030051

Hirschi, Stephan; Kalbermatter, David; Ucurum, Zöhre; Fotiadis, Dimitrios (2020). Cryo-electron microscopic and X-ray crystallographic analysis of the light-driven proton pump proteorhodopsin reveals a pentameric assembly. Journal of structural biology: X, 4(100024), p. 100024. Elsevier 10.1016/j.yjsbx.2020.100024

2019

Hirschi, Stephan; Fischer, Nathalie; Kalbermatter, David; Laskowski, P R; Ucurum, Zöhre; Müller, D J; Fotiadis, Dimitrios (2019). Design and assembly of a chemically switchable and fluorescently traceable light-driven proton pump system for bionanotechnological applications. Scientific reports, 9(1), p. 1046. Springer Nature 10.1038/s41598-018-37260-9

2018

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Colas, Claire; Ucurum Fotiadis, Zöhre; Schlessinger, Avner; Fotiadis, Dimitrios José (2018). Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters. International journal of molecular sciences, 19(3) Molecular Diversity Preservation International MDPI 10.3390/ijms19030918

2017

Laskowski, Pawel R; Pfreundschuh, Moritz; Stauffer, Mirko; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). High-Resolution Imaging and Multiparametric Characterization of Native Membranes by Combining Confocal Microscopy and an Atomic Force Microscopy-Based Toolbox. ACS nano, 11(8), pp. 8292-8301. American Chemical Society 10.1021/acsnano.7b03456

Kalbermatter, David; Chiu, Po-Lin; Jeckelmann, Jean-Marc; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2017). Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change. Journal of structural biology, 199(1), pp. 39-45. Elsevier 10.1016/j.jsb.2017.05.005

Pfreundschuh, Moritz; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José; Müller, Daniel J (2017). Detecting Ligand-Binding Events and Free Energy Landscape while Imaging Membrane Receptors at Subnanometer Resolution. Nano letters, 17(5), pp. 3261-3269. American Chemical Society 10.1021/acs.nanolett.7b00941

2016

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gapsys, Vytautas; Ucurum Fotiadis, Zöhre; de Groot, Bert L; Fotiadis, Dimitrios José (2016). Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 113(37), pp. 10358-10363. National Academy of Sciences NAS 10.1073/pnas.1605442113

Harder, Daniel; Hirschi, Stephan; Ucurum Fotiadis, Zöhre; Goers, Roland; Meier, Wolfgang; Müller, Daniel J; Fotiadis, Dimitrios José (2016). Engineering a Chemical Switch into the Light-driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification. Angewandte Chemie (International ed.), 55(31), pp. 8846-8849. Wiley-VCH 10.1002/anie.201601537

Boggavarapu, Venkata Ravi Naga Rajendr; Hirschi, Stephan; Harder, Daniel; Meury, Marcel; Ucurum Fotiadis, Zöhre; Bergeron, Marc; Fotiadis, Dimitrios José (2016). Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies. In: Mus-Veteau, Isabelle (ed.) Heterologous Expression of Membrane Proteins. Methods and Protocols. Methods in Molecular Biology: Vol. 1432 (pp. 223-242). New York: Springer 10.1007/978-1-4939-3637-3_14

2015

Kalbermatter, David; Jeckelmann, Jean-Marc; Chiu, Po-Lin; Ucurum Fotiadis, Zöhre; Walz, Thomas; Fotiadis, Dimitrios José (2015). 2D and 3D crystallization of the wild-type IIC domain of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 191(3), pp. 376-380. Elsevier 10.1016/j.jsb.2015.08.003

Boggavarapu, Venkata Ravi Naga Rajendr; Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2015). Role of electrostatic interactions for ligand recognition and specificity of peptide transporters. BMC biology, 13(58), p. 58. BioMed Central 10.1186/s12915-015-0167-8

2014

Jeckelmann, Jean-Marc; Harder, Daniel; Ucurum Fotiadis, Zöhre; Fotiadis, Dimitrios José (2014). 2D and 3D crystallization of a bacterial homologue of human vitamin C membrane transport proteins. Journal of structural biology, 188(1), pp. 87-91. Elsevier 10.1016/j.jsb.2014.08.004

Ilgü, Hüseyin; Jeckelmann, Jean-Marc; Gachet Otanez, Maria Salomé; Boggavarapu, Venkata Ravi Naga Rajendr; Ucurum Fotiadis, Zöhre; Gertsch, Jürg; Fotiadis, Dimitrios José (2014). Variation of the detergent-binding capacity and phospholipid content of membrane proteins when purified in different detergents. Biophysical journal, 106(8), pp. 1660-1670. Biophysical Society 10.1016/j.bpj.2014.02.024

2013

Bippes, Christian A.; Ge, Lin; Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Daniel, Hannelore; Fotiadis, Dimitrios; Müller, Daniel J. (2013). Peptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding. Proceedings of the National Academy of Sciences of the United States of America - PNAS, 110(42), E3978-E3986. National Academy of Sciences NAS 10.1073/pnas.1312959110

Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Harder, Daniel; Schneider, Philipp; Ucurum, Zöhre; Hediger, Matthias; Fotiadis, Dimitrios (2013). Expression, purification and low-resolution structure of human vitamin C transporter SVCT1 (SLC23A1). PLoS ONE, 8(10), e76427. Public Library of Science 10.1371/journal.pone.0076427

2012

Bruning, Marc; Barsukov, Igor; Franke, Barbara; Barbieri, Sonia; Volk, Martin; Leopoldseder, Sonja; Ucurum, Zöhre; Mayans, Olga (2012). The intracellular Ig fold: a robust protein scaffold for the engineering of molecular recognition. Protein engineering, design & selection, 25(5), pp. 205-12. Oxford: Oxford University Press 10.1093/protein/gzs007

2011

Jeckelmann, Jean-Marc; Harder, Daniel; Mari, Stefania A; Meury, Marcel; Ucurum, Zöhre; Müller, Daniel J; Erni, Bernhard; Fotiadis, Dimitrios (2011). Structure and function of the glucose PTS transporter from Escherichia coli. Journal of structural biology, 176(3), pp. 395-403. San Diego, Calif.: Elsevier 10.1016/j.jsb.2011.09.012

Bergeron, Marc J.; Boggavarapu, Rajendra; Meury, Marcel; Ucurum, Zöhre; Caron, Luc; Isenring, Paul; Hediger, Matthias A.; Fotiadis, Dimitrios (2011). Frog oocytes to unveil the structure and supramolecular organization of human transport proteins. PLoS ONE, 6(7), e21901. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0021901

Meury, Marcel; Harder, Daniel; Ucurum, Zöhre; Boggavarapu, Rajendra; Jeckelmann, Jean-Marc; Fotiadis, Dimitrios (2011). Structure determination of channel and transport proteins by high-resolution microscopy techniques. Biological chemistry, 392(1-2), pp. 143-50. Berlin: Walter de Gruyter 10.1515/BC.2011.004

2010

Bruning, M; Kreplak, L; Leopoldseder, S; Müller, SA; Tingler, P; Duchesne, L; Ferning, DG; Engel, A; Ucurum-Fotiadis, Z; Mayans, O (2010). Biparte Design of a Self-Fibrillating Protein Copolymer with Nanopatterned Peptide Display Capabilites. Nano letters, 10(11)(Nov 2010), pp. 4533-4537. Washington, D.C.: American Chemical Society 10.1021/nl1024886

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