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Chalkou, Konstantina; Hamza, Tasnim; Benkert, Pascal; Kuhle, Jens; Zecca, Chiara; Simoneau, Gabrielle; Pellegrini, Fabio; Manca, Andrea; Egger, Matthias; Salanti, Georgia (2024). Combining randomized and non-randomized data to predict heterogeneous effects of competing treatments. (In Press). Research Synthesis Methods Wiley 10.1002/jrsm.1717
Oechtering, Johanna; Stein, Kerstin; Schaedelin, Sabine A; Maceski, Aleksandra M; Orleth, Annette; Meier, Stephanie; Willemse, Eline; Qureshi, Ferhan; Heijnen, Ingmar; Regeniter, Axel; Derfuss, Tobias; Benkert, Pascal; D'Souza, Marcus; Limberg, Marguerite; Fischer-Barnicol, Bettina; Achtnichts, Lutz; Mueller, Stefanie; Salmen, Anke; Lalive, Patrice H; Bridel, Claire; ... (2024). Complement Activation Is Associated With Disease Severity in Multiple Sclerosis. Neurology: Neuroimmunology and Neuroinflammation, 11(2), e200212. Wolters Kluwer Health 10.1212/NXI.0000000000200212
Galbusera, Riccardo; Bahn, Erik; Weigel, Matthias; Cagol, Alessandro; Lu, Po-Jui; Schaedelin, Sabine A; Franz, Jonas; Barakovic, Muhamed; Rahmanzadeh, Reza; Dechent, Peter; Nair, Govind; Brück, Wolfgang; Kuhle, Jens; Kappos, Ludwig; Stadelmann, Christine; Granziera, Cristina (2024). Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis. Neurology, 102(3), e207966. American Academy of Neurology 10.1212/WNL.0000000000207966
Cagol, Alessandro; Benkert, Pascal; Melie-Garcia, Lester; Schaedelin, Sabine A.; Leber, Selina; Tsagkas, Charidimos; Barakovic, Muhamed; Galbusera, Riccardo; Lu, Po-Jui; Weigel, Matthias; Ruberte, Esther; Radue, Ernst-Wilhelm; Yaldizli, Özgür; Oechtering, Johanna; Lorscheider, Johannes; D'Souza, Marcus; Fischer-Barnicol, Bettina; Müller, Stefanie; Achtnichts, Lutz; Vehoff, Jochen; ... (2024). Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS. Neurology, 102(1) Wolters Kluwer Health 10.1212/WNL.0000000000207768
Abdelhak, Ahmed; Benkert, Pascal; Schaedelin, Sabine; Boscardin, W John; Cordano, Christian; Oechtering, Johanna; Ananth, Kirtana; Granziera, Cristina; Melie-Garcia, Lester; Montes, Shivany Condor; Beaudry-Richard, Alexandra; Achtnichts, Lutz; Oertel, Frederike C; Lalive, Patrice H; Leppert, David; Müller, Stefanie; Henry, Roland G; Pot, Caroline; Matthias, Amandine; Salmen, Anke; ... (2023). Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis. JAMA neurology, 80(12), pp. 1317-1325. American Medical Association 10.1001/jamaneurol.2023.3997
Todea, Alexandra Ramona; Melie-Garcia, Lester; Barakovic, Muhamed; Cagol, Alessandro; Rahmanzadeh, Reza; Galbusera, Riccardo; Lu, Po-Jui; Weigel, Matthias; Ruberte, Esther; Radue, Ernst-Wilhelm; Schaedelin, Sabine; Benkert, Pascal; Oezguer, Yaldizli; Sinnecker, Tim; Müller, Stefanie; Achtnichts, Lutz; Vehoff, Jochen; Disanto, Giulio; Findling, Oliver; Chan, Andrew; ... (2023). A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients. Journal of magnetic resonance imaging, 58(3), pp. 864-876. Wiley Interscience 10.1002/jmri.28618
Telser, Julia; Grossmann, Kirsten; Weideli, Ornella C; Hillmann, Dorothea; Aeschbacher, Stefanie; Wohlwend, Niklas; Velez, Laura; Kuhle, Jens; Maleska, Aleksandra; Benkert, Pascal; Risch, Corina; Conen, David; Risch, Martin; Risch, Lorenz (2023). Concentrations of Serum Brain Injury Biomarkers Following SARS-CoV-2 Infection in Individuals with and without Long-COVID-Results from the Prospective Population-Based COVI-GAPP Study. Diagnostics, 13(13) MDPI 10.3390/diagnostics13132167
Meier, Stephanie; Willemse, Eline A J; Schaedelin, Sabine; Oechtering, Johanna; Lorscheider, Johannes; Melie-Garcia, Lester; Cagol, Alessandro; Barakovic, Muhamed; Galbusera, Riccardo; Subramaniam, Suvitha; Barro, Christian; Abdelhak, Ahmed; Thebault, Simon; Achtnichts, Lutz; Lalive, Patrice; Müller, Stefanie; Pot, Caroline; Salmen, Anke; Disanto, Giulio; Zecca, Chiara; ... (2023). Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis. JAMA neurology, 80(3), pp. 287-297. American Medical Association 10.1001/jamaneurol.2022.5250
Hamza, Tasnim; Chalkou, Konstantina; Pellegrini, Fabio; Kuhle, Jens; Benkert, Pascal; Lorscheider, Johannes; Zecca, Chiara; Iglesias-Urrutia, Cynthia P; Manca, Andrea; Furukawa, Toshi A; Cipriani, Andrea; Salanti, Georgia (2023). Synthesizing cross-design evidence and cross-format data using network meta-regression. Research Synthesis Methods, 14(2), pp. 283-300. Wiley 10.1002/jrsm.1619
Friedli, Christoph; Salmen, Anke; Hoepner, Robert; Achtnichts, Lutz; Bigi, Sandra; Derfuss, Tobias; Gobbi, Claudio; Kamber, Nicole; Kamm, Christian P; Kuhle, Jens; Lalive, Patrice; Müller, Stefanie; Papadopoulou, Athina; Pot, Caroline; Zecca, Chiara; Chan, Andrew (2023). Specific Aspects of Immunotherapy for Multiple Sclerosis in Switzerland—A Structured Commentary, Update 2022. Clinical and translational neuroscience, 7(1), p. 2. MDPI 10.3390/ctn7010002
Achtnichts, Lutz; Zecca, Chiara; Findling, Oliver; Kamm, Christian P; Mueller, Stefanie; Kuhle, Jens; Lutterotti, Andreas; Gobbi, Claudio; Viviani, Camille; Villiger-Borter, Emanuela; Nedeltchev, Krassen (2023). Correlation of disability with quality of life in patients with multiple sclerosis treated with natalizumab: primary results and post hoc analysis of the TYSabri ImPROvement study (PROTYS). BMJ neurology open, 5(1), e000304. British Medical Association 10.1136/bmjno-2022-000304
Nittas, Vasileios; Zecca, Chiara; Kamm, Christian P; Kuhle, Jens; Chan, Andrew; von Wyl, Viktor (2023). Digital health for chronic disease management: An exploratory method to investigating technology adoption potential. PLoS ONE, 18(4), e0284477. Public Library of Science 10.1371/journal.pone.0284477
Stanikić, Mina; Salmen, Anke; Chan, Andrew; Kuhle, Jens; Kaufmann, Marco; Ammann, Sabin; Schafroth, Sandra; Rodgers, Stephanie; Haag, Christina; Pot, Caroline; Kamm, Christian P; Zecca, Chiara; Gobbi, Claudio; Calabrese, Pasquale; Manjaly, Zina-Mary; von Wyl, Viktor (2022). Association of age and disease duration with comorbidities and disability: A study of the Swiss Multiple Sclerosis Registry. Multiple Sclerosis and Related Disorders, 67, p. 104084. Elsevier 10.1016/j.msard.2022.104084
Le, Ngoc Dung; Steinfort, Marel; Grandgirard, Denis; Maleska, Aleksandra; Leppert, David; Kuhle, Jens; Leib, Stephen L (2022). The CCR5 antagonist maraviroc exerts limited neuroprotection without improving neurofunctional outcome in experimental pneumococcal meningitis. Scientific reports, 12(1), p. 12945. Springer Nature 10.1038/s41598-022-17282-0
Cagol, Alessandro; Schaedelin, Sabine; Barakovic, Muhamed; Benkert, Pascal; Todea, Ramona-Alexandra; Rahmanzadeh, Reza; Galbusera, Riccardo; Lu, Po-Jui; Weigel, Matthias; Melie-Garcia, Lester; Ruberte, Esther; Siebenborn, Nina; Battaglini, Marco; Radue, Ernst-Wilhelm; Yaldizli, Özgür; Oechtering, Johanna; Sinnecker, Tim; Lorscheider, Johannes; Fischer-Barnicol, Bettina; Müller, Stefanie; ... (2022). Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis. JAMA neurology, 79(7), pp. 682-692. American Medical Association 10.1001/jamaneurol.2022.1025
Wai, Chi Ho; Jin, Jessica; Cyrklaff, Marek; Genoud, Christel; Funaya, Charlotta; Sattler, Julia; Maceski, Aleksandra; Meier, Stephanie; Heiland, Sabine; Lanzer, Michael; Frischknecht, Friedrich; Kuhle, Jens; Bendszus, Martin; Hoffmann, Angelika (2022). Neurofilament light chain plasma levels are associated with area of brain damage in experimental cerebral malaria. Scientific reports, 12(1), p. 10726. Springer Nature 10.1038/s41598-022-14291-x
Oechtering, Johanna; Lincke, Therese; Schaedelin, Sabine; Décard, Bernhard F; Maceski, Aleksandra; Orleth, Annette; Meier, Stephanie; Willemse, Eline; Buchmann, Arabella; Khalil, Michael; Derfuss, Tobias; Benkert, Pascal; Heijnen, Ingmar; Regeniter, Axel; Müller, Stefanie; Achtnichts, Lutz; Lalive, Patrice; Salmen, Anke; Pot, Caroline; Gobbi, Claudio; ... (2022). Intrathecal IgM synthesis is associated with spinal cord manifestation and neuronal injury in early MS. Annals of neurology, 91(6), pp. 814-820. Wiley 10.1002/ana.26348
Polymeris, Alexandros A.; Helfenstein, Fabrice; Benkert, Pascal; Aeschbacher, Stefanie; Leppert, David; Coslovsky, Michael; Willemse, Eline; Schaedelin, Sabine; Blum, Manuel R.; Rodondi, Nicolas; Reichlin, Tobias; Moschovitis, Giorgio; Wuerfel, Jens; De Marchis, Gian Marco; Engelter, Stefan T.; Lyrer, Philippe A.; Conen, David; Kühne, Michael; Osswald, Stefan; Bonati, Leo H.; ... (2022). Renal Function and Body Mass Index Contribute to Serum Neurofilament Light Chain Levels in Elderly Patients With Atrial Fibrillation. Frontiers in neuroscience, 16, p. 819010. Frontiers Research Foundation 10.3389/fnins.2022.819010
Benkert, Pascal; Meier, Stephanie; Schaedelin, Sabine; Manouchehrinia, Ali; Yaldizli, Özgür; Maceski, Aleksandra; Oechtering, Johanna; Achtnichts, Lutz; Conen, David; Derfuss, Tobias; Lalive, Patrice H; Mueller, Christian; Müller, Stefanie; Naegelin, Yvonne; Oksenberg, Jorge R; Pot, Caroline; Salmen, Anke; Willemse, Eline; Kockum, Ingrid; Blennow, Kaj; ... (2022). Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study. The lancet. Neurology, 21(3), pp. 246-257. Elsevier 10.1016/S1474-4422(22)00009-6
Hirzel, Cédric; Grandgirard, Denis; Surial, Bernard; Wider, Manon F.; Leppert, David; Kuhle, Jens; Walti, Laura N.; Schefold, Joerg C.; Spinetti, Thibaud; Suter-Riniker, Franziska; Dijkman, Ronald; Leib, Stephen L (2022). Neuro-axonal injury in COVID-19: the role of systemic inflammation and SARS-CoV-2 specific immune response. Therapeutic advances in neurological disorders, 15, p. 17562864221080528. Sage 10.1177/17562864221080528
Chalkou, Konstantina; Steyerberg, Ewout; Bossuyt, Patrick; Subramaniam, Suvitha; Benkert, Pascal; Kuhle, Jens; Disanto, Giulio; Kappos, Ludwig; Zecca, Chiara; Egger, Matthias; Salanti, Georgia (2021). Development, validation and clinical usefulness of a prognostic model for relapse in relapsing-remitting multiple sclerosis. Diagnostic and prognostic research, 5(1), p. 17. BioMed Central 10.1186/s41512-021-00106-6
Oechtering, Johanna; Schaedelin, Sabine; Benkert, Pascal; Müller, Stefanie; Achtnichts, Lutz; Vehoff, Jochen; Disanto, Giulio; Findling, Oliver; Fischer-Barnicol, Bettina; Orleth, Annette; Chan, Andrew; Pot, Caroline; Barakovic, Muhamed; Rahmanzadeh, Reza; Galbusera, Riccardo; Heijnen, Ingmar; Lalive, Patrice H; Wuerfel, Jens; Subramaniam, Suvitha; Aeschbacher, Stefanie; ... (2021). Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis. Annals of neurology, 90(3), pp. 477-489. Wiley-Blackwell 10.1002/ana.26137
Rodgers, Stephanie; Manjaly, Zina-Mary; Calabrese, Pasquale; Steinemann, Nina; Kaufmann, Marco; Salmen, Anke; Chan, Andrew; Kesselring, Jürg; Kamm, Christian P.; Kuhle, Jens; Zecca, Chiara; Gobbi, Claudio; von Wyl, Viktor; Ajdacic-Gross, Vladeta (2021). The Effect of Depression on Health-Related Quality of Life Is Mediated by Fatigue in Persons with Multiple Sclerosis. Brain Sciences, 11(6) MDPI 10.3390/brainsci11060751
Rodgers, Stephanie; Calabrese, Pasquale; Ajdacic-Gross, Vladeta; Steinemann, Nina; Kaufmann, Marco; Salmen, Anke; Manjaly, Zina-Mary; Kesselring, Jürg; Kamm, Christian P; Kuhle, Jens; Chan, Andrew; Gobbi, Claudio; Zecca, Chiara; Müller, Stefanie; von Wyl, Viktor (2021). Major depressive disorder subtypes and depression symptoms in multiple sclerosis: What is different compared to the general population? Journal of psychosomatic research, 144, p. 110402. Elsevier 10.1016/j.jpsychores.2021.110402
Polymeris, Alexandros A; Coslovksy, Michael; Aeschbacher, Stefanie; Sinnecker, Tim; Benkert, Pascal; Kobza, Richard; Beer, Jürg; Rodondi, Nicolas; Fischer, Urs; Moschovitis, Giorgio; Monsch, Andreas U; Springer, Anne; Schwenkglenks, Matthias; Wuerfel, Jens; De Marchis, Gian Marco; Lyrer, Philippe A; Kühne, Michael; Osswald, Stefan; Conen, David; Kuhle, Jens; ... (2020). Serum neurofilament light in atrial fibrillation: clinical, neuroimaging and cognitive correlates. Brain Communications, 2(2), fcaa166. Oxford University Press 10.1093/braincomms/fcaa166
Kaufmann, Marco; Salmen, Anke; Barin, Laura; Puhan, Milo Alan; Calabrese, Pasquale; Kamm, Philipp; Gobbi, Claudio; Kuhle, Jens; Manjaly, Zina-Mary; Ajdacic-Gross, Vladeta; Schafroth, Sandra; Bottignole, Britta; Ammann, Sabin; Zecca, Chiara; D'Souza, Marcus; Von Wyl, Viktor (2020). Development and validation of the self-reported disability status scale (SRDSS) to estimate EDSS-categories. Multiple Sclerosis and Related Disorders, 42(102148), p. 102148. Elsevier 10.1016/j.msard.2020.102148
Boligan, Kayluz F.; Oechtering, Johanna; Keller, Christian W; Peschke, Benjamin; Rieben, Robert; Bovin, Nicolai; Kappos, Ludwig; Cummings, Richard D; Kuhle, Jens; von Gunten, Stephan; Lünemann, Jan D (2020). Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS. Neurology: Neuroimmunology and Neuroinflammation, 7(2) Wolters Kluwer Health 10.1212/NXI.0000000000000676
Kaufmann, Marco; Puhan, Milo Alan; Salmen, Anke; Kamm, Christian P.; Manjaly, Zina-Mary; Calabrese, Pasquale; Schippling, Sven; Müller, Stefanie; Kuhle, Jens; Pot, Caroline; Gobbi, Claudio; Steinemann, Nina; von Wyl, Viktor (2020). 60/30: 60% of the Morbidity-Associated Multiple Sclerosis Disease Burden Comes From the 30% of Persons With Higher Impairments. Frontiers in neurology, 11(156), p. 156. Frontiers Media S.A. 10.3389/fneur.2020.00156
Le, Ngoc Dung; Muri, Lukas; Grandgirard, Denis; Kuhle, Jens; Leppert, David; Leib, Stephen L. (2020). Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis. Journal of neuroinflammation, 17(1), p. 293. BioMed Central 10.1186/s12974-020-01966-3
Achtnichts, Lutz; Chan, Andrew; Czaplinski, Adam; Derfuss, Tobias; Du Pasquier, Renaud; Findling, Oliver; Gobbi, Claudio; Hoepner, Robert; Kamber, Nicole; Kamm, Christian P.; Kuhle, Jens; Lalive, Patrice; Lutterotti, Andreas; Martin, Roland; Mller, Stefanie; Papadopoulou, Athina; Pot, Caroline; Salmen, Anke; Schippling, Sven and Zecca, Chiara (2019). Besonderheiten der Immuntherapie der Multiplen Sklerose in der Schweiz. Swiss Medical Forum, 19(41-42), pp. 676-685. EMH Swiss Medical Publishers 10.4414/smf.2019.08356
Kaufmann, Marco; Puhan, Milo Alan; Kuhle, Jens; Yaldizli, Özgür; Magnusson, Tomas; Kamm, Christian P.; Calabrese, Pasquale; von Wyl, Viktor (2019). A Framework for Estimating the Burden of Chronic Diseases: Design and Application in the Context of Multiple Sclerosis. Frontiers in neurology, 10, p. 953. Frontiers Media S.A. 10.3389/fneur.2019.00953
Steinemann, Nina; Kuhle, Jens; Calabrese, Pasquale; Kesselring, Jürg; Disanto, Giulio; Merkler, Doron; Pot, Caroline; Ajdacic-Gross, Vladeta; Rodgers, Stephanie; Puhan, Milo Alan; von Wyl, Viktor (2018). The Swiss Multiple Sclerosis Registry (SMSR): study protocol of a participatory, nationwide registry to promote epidemiological and patient-centered MS research. BMC neurology, 18(1), p. 111. BioMed Central 10.1186/s12883-018-1118-0
De Marchis, Gian Marco; Katan, Mira; Barro, Christian; Fladt, Joachim; Traenka, Christopher; Seiffge, David J; Hert, Lisa; Gensicke, Henrik; Disanto, Giulio; Sutter, Raoul; Peters, Nils; Sarikaya, Hakan; Goeggel Simonetti, Barbara; El-Koussy, Marwan; Engelter, Stephan; Lyrer, Philippe A; Christ-Crain, Mirjam; Arnold, Marcel; Kuhle, Jens and Bonati, Leo (2018). Serum Neurofilament Light Chain in Patients with Acute Cerebrovascular Events. European journal of neurology, 25(3), pp. 562-568. Wiley-Blackwell 10.1111/ene.13554
Barin, Laura; Salmen, Anke; Disanto, Giulio; Babačić, Haris; Calabrese, Pasquale; Chan, Andrew; Kamm, Christian P.; Kesselring, Jürg; Kuhle, Jens; Gobbi, Claudio; Pot, Caroline; Puhan, Milo A.; von Wyl, Viktor (2018). The disease burden of Multiple Sclerosis from the individual and population perspective: Which symptoms matter most? Multiple Sclerosis and Related Disorders, 25, pp. 112-121. Elsevier 10.1016/j.msard.2018.07.013
Disanto, Giulio; Barro, Christian; Benkert, Pascal; Naegelin, Yvonne; Schädelin, Sabine; Giardiello, Antonella; Zecca, Chiara; Blennow, Kaj; Zetterberg, Henrik; Leppert, David; Kappos, Ludwig; Gobbi, Claudio; Kuhle, Jens (2017). Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosis. Annals of neurology, 81(6), pp. 857-870. Wiley-Blackwell 10.1002/ana.24954
Disanto, Giulio; Benkert, Pascal; Lorscheider, Johannes; Mueller, Stefanie; Vehoff, Jochen; Zecca, Chiara; Ramseier, Simon; Achtnichts, Lutz; Findling, Oliver; Nedeltchev, Krassen; Radue, Ernst-Wilhelm; Sprenger, Till; Stippich, Christoph; Derfuss, Tobias; Louvion, Jean-François; Kamm, Christian Philipp; Mattle, Heinrich; Lotter, Christoph; Du Pasquier, Renaud; Schluep, Myriam; ... (2016). The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options. PLoS ONE, 11(3), e0152347. Public Library of Science 10.1371/journal.pone.0152347
