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Number of items at this level: 91.

2017

Sendi, Parham; Hirzel, Cédric; Pfister, Stefan; Ackermann-Gäumann, Rahel; Grandgirard, Denis; Hewer, Ekkehard; Nirkko, Arto Christian (2017). Fatal Outcome of Tick-borne Encephalitis after Vaccine Failure. Frontiers in neurology, 8(119) Frontiers Media S.A. 10.3389/fneur.2017.00119

2016

Brugger, Silvio; Troxler, Lukas; Rüfenacht, Susanne; Frey, Pascal Marcel; Morand, Brigitte; Geyer, Rudolf; Mühlemann, Kathrin; Höck, Stefan; Thormann, Wolfgang; Furrer, Julien; Christen, Stephan; Hilty, Markus (2016). Polysaccharide capsule composition of pneumococcal serotype 19A subtypes: Unaltered among subtypes and independent of the nutritional environment. Infection and immunity, 84(11), pp. 3152-3160. American Society for Microbiology 10.1128/IAI.00474-16

Perny, Michael; Roccio, Marta; Grandgirard, Denis; Solyga, Magdalena; Senn, Pascal; Leib, Stephen (2016). The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. Journal of neuroscience, 36(29), pp. 7740-7749. Society for Neuroscience 10.1523/JNEUROSCI.0554-16.2016

Curiao, Tânia; Marchi, Emmanuela; Grandgirard, Denis; León-Sampedro, Ricardo; Viti, Carlo; Leib, Stephen; Baquero, Fernando; Oggioni, Marco R; Martinez, José Luis; Coque, Teresa M (2016). Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure. BMC Genomics, 17(491), p. 491. BioMed Central 10.1186/s12864-016-2778-z

Balmer, Maria Luisa; Ma, Eric H; Bantug, Glenn R; Grählert, Jasmin; Pfister, Simona; Glatter, Timo; Jauch, Annaïse; Dimeloe, Sarah; Slack, Emma; Dehio, Philippe; Krzyzaniak, Magdalena A; King, Carolyn G; Burgener, Anne-Valérie; Fischer, Marco; Develioglu, Leyla; Belle, Réka; Recher, Mike; Bonilla, Weldy V; Macpherson, Andrew; Hapfelmeier, Siegfried Hektor; ... (2016). Memory CD8(+) T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. Immunity, 44(6), pp. 1312-1324. Cell Press 10.1016/j.immuni.2016.03.016

Hauser, Christoph; Kronenberg, Andreas; Allemann, Aurélie; Mühlemann, Kathrin; Hilty, Markus (2016). Serotype/serogroup-specific antibiotic non-susceptibility of invasive and non-invasive Streptococcus pneumoniae, Switzerland, 2004 to 2014. Euro surveillance, 21(21) Institut de Veille Sanitaire 10.2807/1560-7917.ES.2016.21.21.30239

van de Beek, D; Cabellos, C; Dzupova, O; Esposito, S; Klein, M; Kloek, A T; Leib, Stephen; Mourvillier, B; Ostergaard, C; Pagliano, P; Pfister, H W; Read, R C; Sipahi, O Resat; Brouwer, M C (2016). ESCMID guideline: diagnosis and treatment of acute bacterial meningitis. Clinical microbiology and infection, 22(Suppl 3), S37-S62. Blackwell Publishing 10.1016/j.cmi.2016.01.007

Gomez de Agüero Tamargo, Maria de la Mercedes; Ganal-Vonarburg, Stephanie C; Fuhrer, Tobias; Rupp, Sandra Carina; Uchimura, Yasuhiro; Li, Hai; Steinert, Anna; Heikenwalder, Mathias; Hapfelmeier, Siegfried Hektor; Sauer, Uwe; McCoy, Kathleen; Macpherson, Andrew (2016). The maternal microbiota drives early postnatal innate immune development. Science, 351(6279), pp. 1296-1302. American Association for the Advancement of Science 10.1126/science.aad2571

Fernández-López, David; Faustino, Joel; Klibanov, Alexander L; Derugin, Nikita; Blanchard, Elodie; Simon, Franziska; Leib, Stephen; Vexler, Zinaida S (2016). Microglial Cells Prevent Hemorrhage in Neonatal Focal Arterial Stroke. Journal of neuroscience, 36(10), pp. 2881-2893. Society for Neuroscience 10.1523/JNEUROSCI.0140-15.2016

Bürki, Sarah Elisabeth; Grandgirard, Denis; Datta, Alexandre N; Hackenberg, Annette; Martin, Florence; Schmitt-Mechelke, Thomas; Leib, Stephen L; Steinlin, Maja (2016). Inflammatory markers in pediatric stroke: An attempt to better understanding the pathophysiology. European journal of paediatric neurology, 20(2), pp. 252-260. Elsevier 10.1016/j.ejpn.2015.12.006

Bally, Lia; Grandgirard, Denis; Leib, Stephen (2016). Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. Antimicrobial agents and chemotherapy, 60(3), pp. 1841-1846. American Society for Microbiology 10.1128/AAC.02429-15

Hathaway, Lucy Jane; Grandgirard, Denis; Valente, Luca Gabriele; Täuber, Martin G.; Leib, Stephen (2016). Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis. Open Biology, 6(3) The Royal Society Publishing 10.1098/rsob.150269

Zürcher, Patrick; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Grossholz, Marius; Jakob, Stephan; Takala, Jukka; Hänggi, Matthias (2016). A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model. BMC neurology, 16, p. 43. BioMed Central 10.1186/s12883-016-0565-8

Baumgartner, Denja; Aebi, Susanne; Grandgirard, Denis; Leib, Stephen; Draeger, Annette; Babiychuk, Eduard; Hathaway, Lucy Jane (2016). Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes. BMC microbiology, 16(1), p. 154. BioMed Central 10.1186/s12866-016-0777-5

Cuenca Vera, Miguelangel; Pfister, Simona; Buschor, Stefanie; Bayramova, Firuza; Hernandez, Sara B.; Cava, Felipe; Kuru, Erkin; Van Nieuwenhze, Michael S.; Brun, Yves V.; Matos Coelho, Fernanda; Hapfelmeier, Siegfried Hektor (2016). D-Alanine-Controlled Transient Intestinal Mono-Colonization with Non-Laboratory-Adapted Commensal E. coli Strain HS. PLoS ONE, 11(3), e0151872. Public Library of Science 10.1371/journal.pone.0151872

Moor, Kathrin; Wotzka, Sandra Y; Toska, Albulena; Diard, Médéric; Hapfelmeier, Siegfried Hektor; Slack, Emma (2016). Peracetic Acid Treatment Generates Potent Inactivated Oral Vaccines from a Broad Range of Culturable Bacterial Species. Frontiers in immunology, 7(34), p. 34. Frontiers Research Foundation 10.3389/fimmu.2016.00034

Studer, Nicolas; Desharnais, Lyne; Beutler, Markus; Brugiroux, Sandrine; Terrazos Miani, Miguel Angel; Menin, Laure; Schürch, Christian; McCoy, Kathy D.; Kuehne, Sarah A.; Minton, Nigel P.; Stecher, Bärbel; Bernier-Latmani, Rizlan; Hapfelmeier, Siegfried Hektor (2016). Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse Model. Frontiers in Cellular and Infection Microbiology, 6(191) Frontiers 10.3389/fcimb.2016.00191

2015

Chevalier, Claire; Stojanović, Ozren; Colin, Didier J; Suarez-Zamorano, Nicolas; Tarallo, Valentina; Veyrat-Durebex, Christelle; Rigo, Dorothée; Fabbiano, Salvatore; Stevanović, Ana; Hagemann, Stefanie Claudia; Montet, Xavier; Seimbille, Yann; Zamboni, Nicola; Hapfelmeier, Siegfried Hektor; Trajkovski, Mirko (2015). Gut Microbiota Orchestrates Energy Homeostasis during Cold. Cell, 163(6), pp. 1360-1374. Cell Press 10.1016/j.cell.2015.11.004

Suárez-Zamorano, Nicolas; Fabbiano, Salvatore; Chevalier, Claire; Stojanović, Ozren; Colin, Didier J; Stevanović, Ana; Veyrat-Durebex, Christelle; Tarallo, Valentina; Rigo, Dorothée; Germain, Stéphane; Ilievska, Miroslava; Montet, Xavier; Seimbille, Yann; Hapfelmeier, Siegfried Hektor; Trajkovski, Mirko (2015). Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nature medicine, 21(12), pp. 1497-1501. Nature Publishing Group 10.1038/nm.3994

Frick, Tamara; Springe, Dirk; Grandgirard, Denis; Leib, Stephen; Hänggi, Matthias (2015). An improved simple rat model for global cerebral ischaemia by induced cardiac arrest. Neurological research, 38(4), pp. 373-380. Maney 10.1179/1743132815Y.0000000090

Liechti, Fabian D; Grandgirard, Denis; Leib, Stephen (2015). Bacterial meningitis: insights into pathogenesis and evaluation of new treatment options: a perspective from experimental studies. Future microbiology, 10(7), pp. 1195-1213. Future Medicine 10.2217/fmb.15.43

Liechti, F D; Grandgirard, Denis; Leib, Stephen (2015). The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis. Neuroscience, 297, pp. 89-94. Elsevier 10.1016/j.neuroscience.2015.03.056

Grandgirard, Denis; Furi, Leonardo; Ciusa, Maria Laura; Baldassarri, Lucilla; Knight, Daniel R; Morrissey, Ian; Largiadèr, Carlo Rodolfo; Leib, Stephen; Oggioni, Marco R (2015). Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression. BMC Genomics, 16(345), p. 345. BioMed Central 10.1186/s12864-015-1544-y

Wang, Junhua; Vuitton, Dominique A; Müller, Norbert; Hemphill, Andrew; Spiliotis, Markus; Blagosklonov, Oleg; Grandgirard, Denis; Leib, Stephen; Shalev, Itay; Levy, Gary; Lu, Xiaomei; Lin, Renyong; Wen, Hao; Gottstein, Bruno (2015). Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4+ CD25+ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice. PLoS neglected tropical diseases, 9(5), e0003755. Public Library of Science 10.1371/journal.pntd.0003755

Spaniol, Violeta; Bernhard, Sara; Aebi, Christoph (2015). Moraxella catarrhalis AcrAB-OprM efflux pump contributes to antimicrobial resistance and is enhanced during cold shock response. Antimicrobial agents and chemotherapy, 59(4), pp. 1886-1894. American Society for Microbiology 10.1128/AAC.03727-14

Bendel, Stepani; Springe, Dirk; Pereira, Adriano José; Grandgirard, Denis; Leib, Stephen; Putzu, Alessandro; Schlickeiser, Jannis; Jakob, Stephan M.; Takala, Jukka; Hänggi, Matthias (2015). Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? BMC Anaesthesiology, 15(2), p. 2. Biomed Central 10.1186/1471-2253-15-2

Liechti, Fabian D; Bächtold, Fabian; Grandgirard, Denis; Leppert, David; Leib, Stephen (2015). The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis. Journal of neuroinflammation, 12(43), p. 43. BioMed Central 10.1186/s12974-015-0257-0

2014

Ricci, Susanna; Grandgirard, Denis; Wenzel, Michael; Braccini, Tiziana; Salvatore, Paola; Oggioni, Marco R; Leib, Stephen; Koedel, Uwe (2014). Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis. BMC infectious diseases, 14(726), p. 726. BioMed Central 10.1186/s12879-014-0726-6

Hilty, Markus; Wüthrich, Daniel; Salter, Susannah J; Engel, Hans Jürg; Campbell, Samuel; Sá-Leão, Raquel; de Lencastre, Hermínia; Hermans, Peter; Sadowy, Ewa; Turner, Paul; Chewapreecha, Claire; Diggle, Mathew; Pluschke, Gerd; McGee, Lesley; Eser, Ozgen Köseoğlu; Low, Donald E; Smith-Vaughan, Heidi; Endimiani, Andrea; Küffer, Marianne; Dupasquier, Mélanie; ... (2014). Global phylogenomic analysis of nonencapsulated Streptococcus pneumoniae reveals a deep-branching classic lineage that is distinct from multiple sporadic lineages. Genome biology and evolution, 6(12), pp. 3281-3294. Oxford University Press 10.1093/gbe/evu263

Maffioli, Carola; Grandgirard, Denis; Engler, Olivier; Leib, Stephen (2014). A tick-borne encephalitis model in infant rats infected with langat virus. Journal of neuropathology and experimental neurology, 73(12), pp. 1107-1115. Lippincott Williams & Wilkins 10.1097/NEN.0000000000000131

Balmer, Maria L; Schürch, Christian; Saito, Yasuyuki; Geuking, Markus; Li, Hai; Cuenca, Miguelangel; Kovtonyuk, Larisa V; McCoy, Kathleen; Hapfelmeier, Siegfried; Ochsenbein, Adrian; Manz, Markus G; Slack, Emma; Macpherson, Andrew (2014). Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling. Journal of immunology, 193(10), pp. 5273-5283. American Association of Immunologists 10.4049/jimmunol.1400762

Coutinho, Leonam G; Christen, Stephan; Bellac, Caroline L; Fontes, Fabrícia; de Souza, Fladjule; Grandgirard, Denis; Leib, Stephen; Agnez-Lima, Lucymara F (2014). The kynurenine pathway is involved in bacterial meningitis. Journal of neuroinflammation, 11(169), p. 169. BioMed Central 10.1186/s12974-014-0169-4

Schaffner, Thierry Oliver; Hinds, Jason; Gould, Katherine A; Wüthrich, Daniel; Bruggmann, Rémy; Küffer, Marianne; Mühlemann, Kathrin; Hilty, Markus; Hathaway, Lucy Jane (2014). A point mutation in cpsE renders Streptococcus pneumoniae nonencapsulated and enhances its growth, adherence and competence. BMC microbiology, 14(210), p. 210. BioMed Central 10.1186/s12866-014-0210-x

Meichtry, Jurka; Born, Rita; Küffer, Marianne; Zwahlen, Marcel; Albrich, Werner C.; Brugger, Silvio; Mühlemann, Kathrin; Hilty, Markus (2014). Serotype epidemiology of invasive pneumococcal disease in Swiss adults: A nationwide population-based study. Vaccine, 32(40), pp. 5185-5191. Elsevier 10.1016/j.vaccine.2014.07.060

Balmer, Maria Luisa; Slack, Emma; De Gottardi, Andrea; Lawson, Melissa; Hapfelmeier, Siegfried Hektor; Miele, Luca; Grieco, Antonio; Van Vlierberghe, Hans; Fahrner, René; Patuto, Nicola; Bernsmeier, Christine; Ronchi, Francesca; Wyss, Madeleine; Keogh-Stroka, Deborah M.; Dickgreber, Nina; Heim, Markus H; McCoy, Kathy D; Macpherson, Andrew (2014). The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota. Science translational medicine, 6(237), 237ra66. American Association for the Advancement of Science 10.1126/scitranslmed.3008618

Agyeman, Philipp; Grandgirard, Denis; Leib, Stephen (2014). Pathogenesis and Pathophysiology of Bacterial Infections. In: Scheld, Michael; Whitley, Richard J.; Marra, Christina M. (eds.) Infections of the Central Nervous System (pp. 341-364). Philadelphia, PA, USA: Lippincott Williams & Wilkins

Engel, Hans Jürg; Mika, Moana; Denapaite, Dalia; Hakenbeck, Regine; Mühlemann, Kathrin; Heller, Manfred; Hathaway, Lucy Jane; Hilty, Markus (2014). A low affinity penicillin-binding protein 2x is required for heteroresistance in Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 58(7), pp. 3934-3941. American Society for Microbiology 10.1128/AAC.02547-14

Liechti, Fabian D; Grandgirard, Denis; Leppert, David; Leib, Stephen (2014). Matrix metalloproteinase inhibition lowers mortality and brain injury in experimental pneumococcal meningitis. Infection and immunity, 82(4), pp. 1710-1718. American Society for Microbiology 10.1128/IAI.00073-14

Hirt-Minkowski, Patricia; Marti, Hans-Peter; Hönger, Gideon; Grandgirard, Denis; Leib, Stephen; Amico, Patrizia; Schaub, Stefan (2014). Correlation of serum and urinary matrix metalloproteases/tissue inhibitors of metalloproteases with subclinical allograft fibrosis in renal transplantation. Transplant immunology, 30(1), pp. 1-6. Elsevier 10.1016/j.trim.2013.11.004

Holler, Jon G.; Brandt, Christian T.; Leib, Stephen L.; Rowland, Ian J.; Ostergaard, Christian (2014). Increase in hippocampal water diffusion and volume during experimental pneumococcal meningitis is aggravated by bacteremia. BMC infectious diseases, 14(1), p. 240. BioMed Central 10.1186/1471-2334-14-240

Liechti, Fabian D; Stüdle, Nicolas; Theurillat, Regula; Grandgirard, Denis; Thormann, Wolfgang; Leib, Stephen (2014). The mood-stabilizer lithium prevents hippocampal apoptosis and improves spatial memory in experimental meningitis. PLoS ONE, 9(11), e113607. Public Library of Science 10.1371/journal.pone.0113607

Baranger, Kévin; Rivera, Santiago; Liechti, Fabian D; Grandgirard, Denis; Bigas, Judit; Seco, Jesús; Tarrago, Teresa; Leib, Stephen; Khrestchatisky, Michel (2014). Endogenous and synthetic MMP inhibitors in CNS physiopathology. In: Dityatev, Alexander; Wehrle-Haller, Bernhard; Pitkänen, Asla (eds.) Brain Extracellular Matrix in Health and Disease. Progress in Brain Research: Vol. 214 (pp. 313-351). Elsevier 10.1016/B978-0-444-63486-3.00014-1

2013

Coutinho, Leonam G; Grandgirard, Denis; Leib, Stephen L.; Agnez-Lima, Lucymara F (2013). Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. BMC infectious diseases, 13(1), p. 326. BioMed Central 10.1186/1471-2334-13-326

Spaniol, Violeta; Wyder, Stefan; Aebi, Christoph (2013). RNA-Seq-based analysis of the physiologic cold shock-induced changes in Moraxella catarrhalis gene expression. PLoS ONE, 8(7), e68298. Public Library of Science 10.1371/journal.pone.0068298

Monney, Thierry; Grandgirard, Denis; Leib, Stephen; Hemphill, Andrew (2013). Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model. Pathogens, 2(2), pp. 193-208. MDPI AG 10.3390/pathogens2020193

Grandgirard, Denis; Gäumann, Rahel; Coulibaly, Boubacar; Dangy, Jean-Pierre; Sie, Ali; Junghanss, Thomas; Schudel, Hans; Pluschke, Gerd; Leib, Stephen L. (2013). The causative pathogen determines the inflammatory profile in cerebrospinal fluid and outcome in patients with bacterial meningitis. Mediators of inflammation, 2013, p. 312476. Hindawi Publishing Corp. 10.1155/2013/312476

2012

Fritz, Jörg H; Rojas, Olga Lucia; Simard, Nathalie; McCarthy, Douglas D; Hapfelmeier, Siegfried; Rubino, Stephen; Robertson, Susan J; Larijani, Mani; Gosselin, Jean; Ivanov, Ivaylo I; Martin, Alberto; Casellas, Rafael; Philpott, Dana J; Girardin, Stephen E; McCoy, Kathy D; Macpherson, Andrew J; Paige, Christopher J; Gommerman, Jennifer L (2012). Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature, 481(7380), pp. 199-203. London: Macmillan Journals Ltd. 10.1038/nature10698

Slack, Emma; Balmer, Maria Luisa; Fritz, Jörg H; Hapfelmeier, Siegfried (2012). Functional flexibility of intestinal IgA - broadening the fine line. Frontiers in immunology, 3, p. 100. Lausanne: Frontiers Research Foundation 10.3389/fimmu.2012.00100

Macpherson, Andrew J; Geuking, Markus B; Slack, Emma; Hapfelmeier, Siegfried; McCoy, Kathy D (2012). The habitat, double life, citizenship, and forgetfulness of IgA. Immunological reviews, 245(1), pp. 132-146. Oxford: Wiley-Blackwell 10.1111/j.1600-065X.2011.01072.x

2011

Lüer, Sonja; Troller, Rolf; Jetter, Marion; Spaniol, Violeta; Aebi, Christoph (2011). Topical curcumin can inhibit deleterious effects of upper respiratory tract bacteria on human oropharyngeal cells in vitro: potential role for patients with cancer therapy induced mucositis? Supportive care in cancer, 19(6), pp. 799-806. Berlin: Springer 10.1007/s00520-010-0894-x

Sury, Matthias D.; Vorlet-Fawer, Lorianne; Agarinis, Claudia; Yousefi, Shida; Grandgirard, Denis; Leib, Stephen L.; Christen, Stephan (2011). Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 41(1), pp. 201-208. Amsterdam: Elsevier 10.1016/j.nbd.2010.09.007

Geuking, Markus B; Cahenzli, Julia; Lawson, Melissa A E; Ng, Derek C K; Slack, Emma; Hapfelmeier, Siegfried; McCoy, Kathy D; Macpherson, Andrew J (2011). Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity, 34(5), pp. 794-806. Cambridge, Mass.: Cell Press 10.1016/j.immuni.2011.03.021

Woehrl, Bianca; Klein, Matthias; Grandgirard, Denis; Koedel, Uwe; Leib, Stephen (2011). Bacterial meningitis: current therapy and possible future treatment options. Expert review of anti-infective therapy, 9(11), pp. 1053-1065. London: Expert Reviews 10.1586/ERI.11.129

Hofer, Sandra; Grandgirard, Denis; Burri, Denise; Fröhlich, Tanja K.; Leib, Stephen L. (2011). Bacterial meningitis impairs hippocampal neurogenesis. Journal of neuropathology and experimental neurology, 70(10), pp. 890-899. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/NEN.0b013e3182303f31

Monney, Thierry; Rütti, David; Schorer, Michelle; Debache, Karim; Grandgirard, Denis; Leib, Stephen L.; Hemphill, Andrew (2011). RecNcMIC3-1-R is a microneme- and rhoptry-based chimeric antigen that protects against acute neosporosis and limits cerebral parasite load in the mouse model for Neospora caninum infection. Vaccine, 29(40), pp. 6967-6975. Amsterdam: Elsevier 10.1016/j.vaccine.2011.07.038

Blaser, Cornelia; Wittwer, Matthias; Grandgirard, Denis; Leib, Stephen L. (2011). Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE, 6(3), e17840. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0017840

Margos, M.C.; Grandgirard, Denis; Leib, Stephen; Gottstein, Bruno (2011). In vitro induction of lymph node cell proliferation by mouse bone marrow dendritic cells following stimulation with different Echinococcus multilocularis antigens. Journal of helminthology, 85(2), pp. 128-137. Cambridge: Cambridge University Press 10.1017/S0022149X10000878

Spaniol, Violeta; Troller, Rolf; Schaller, André; Aebi, Christoph (2011). Physiologic cold shock of Moraxella catarrhalis affects the expression of genes involved in the iron acquisition, serum resistance and immune evasion. BMC microbiology, 11, p. 182. London: BioMed Central 10.1186/1471-2180-11-182

2010

Mégevand, C; Gervaix, A; Heininger, U; Berger, C; Aebi, C; Vaudaux, B; Kind, C; Gnehm, H-P; Hitzler, M; Renzi, G; Schrenzel, J; François, P (2010). Molecular epidemiology of the nasal colonization by methicillin-susceptible Staphylococcus aureus in Swiss children. Clinical microbiology and infection, 16(9), pp. 1414-20. Oxford: Blackwell Publishing 10.1111/j.1469-0691.2009.03090.x

Hapfelmeier, Siegfried; Macpherson, Andrew J. (2010). In remembrance of commensal intestinal microbes. Communicative & integrative biology, 3(6), pp. 569-571. Austin, Tex.: Landes Bioscience 10.4161/cib.3.6.13011

Jetter, Marion; Spaniol, Violeta; Troller, Rolf; Aebi, Christoph (2010). Down-regulation of porin M35 in Moraxella catarrhalis by aminopenicillins and environmental factors and its potential contribution to the mechanism of resistance to aminopenicillins. Journal of antimicrobial chemotherapy, 65(10), pp. 2089-96. Oxford: Oxford University Press 10.1093/jac/dkq312

Grandgirard, Denis; Leib, Stephen L. (2010). Meningitis in neonates: bench to bedside. Clinics in perinatology, 37(3), pp. 655-676. New York, N.Y.: Elsevier 10.1016/j.clp.2010.05.004

Wittwer, Matthias; Grandgirard, Denis; Rohrbach, Janine; Leib, Stephen L. (2010). Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis. BMC infectious diseases, 10(176), p. 176. London: BioMed Central 10.1186/1471-2334-10-176

Blaser, Cornelia; Klein, Matthias; Grandgirard, Denis; Wittwer, Matthias; Peltola, Heikki; Weigand, Michael; Koedel, Uwe; Leib, Stephen L. (2010). Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis. BMC infectious diseases, 10(84), p. 84. London: BioMed Central 10.1186/1471-2334-10-84

Grandgirard, Denis; Oberson, Kevin; Bühlmann, Angela; Gäumann, Rahel; Leib, Stephen L. (2010). Attenuation of cerebrospinal fluid inflammation by the nonbacteriolytic antibiotic daptomycin versus that by ceftriaxone in experimental pneumococcal meningitis. Antimicrobial agents and chemotherapy, 54(3), pp. 1323-1326. Washington, D.C.: American Society for Microbiology 10.1128/AAC.00812-09

2009

Slack, Emma; Hapfelmeier, Siegfried; Stecher, Bärbel; Velykoredko, Yuliya; Stoel, Maaike; Lawson, Melissa A E; Geuking, Markus B; Beutler, Bruce; Tedder, Thomas F; Hardt, Wolf-Dietrich; Bercik, Premysl; Verdu, Elena F; McCoy, Kathy D; Macpherson, Andrew J (2009). Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism. Science, 325(5940), pp. 617-620. Washington, D.C.: American Association for the Advancement of Science 10.1126/science.1172747

2008

Spaniol, Violeta; Heiniger, Nadja; Troller, Rolf; Aebi, Christoph (2008). Outer membrane protein UspA1 and lipooligosaccharide are involved in invasion of human epithelial cells by Moraxella catarrhalis. Microbes and infection, 10(1), pp. 3-11. Paris: Elsevier Masson SAS 10.1016/j.micinf.2007.09.014

Gehre, F.; Leib, Stephen L.; Grandgirard, Denis; Kummer, Jürg; Bühlmann, Angela; Simon, Franziska; Gäumann, R.; Kharat, A. S.; Täuber, Martin G.; Tomasz, A. (2008). Essential role of choline for pneumococcal virulence in an experimental model of meningitis. Internal medicine journal, 264(2), pp. 143-154. Sydney: Blackwell 10.1111/j.1365-2796.2008.01930.x

Sury, Matthias D.; Agarinis, Claudia; Widmer, Hans-Rudolf; Leib, Stephen L.; Christen, Stephan (2008). JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiology of disease, 32(1), pp. 142-150. Amsterdam: Elsevier 10.1016/J.nbd.2008.07.006

Sellner, Johann; Greeve, Isabell; Findling, Oliver; Kamm, Christian P.; Minten, Carsten; Engelhardt, Britta; Grandgirard, Denis; Leib, Stephen L.; Mattle, Heinrich P (2008). Effect of interferon-beta and atorvastatin on Th1/Th2 cytokines in multiple sclerosis. Neurochemistry international, 53(1-2), pp. 17-21. Amsterdam: Elsevier 10.1016/j.neuint.2008.04.004

Grandgirard, Denis; Loeffler, Jutta M.; Fischetti, Vincent A.; Leib, Stephen L. (2008). Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis. Journal of infectious diseases, 197(11), pp. 1519-1522. Cary, N.C.: Oxford University Press 10.1086/587942

Sellner, Johann; Greeve, I; Findling, O; Grandgirard, Denis; Leib, Stephen L.; Mattle, H P (2008). Atorvastatin does not alter serum levels of sCD95 and sCD95L in multiple sclerosis. Clinical and experimental immunology, 152(2), pp. 280-284. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2249.2008.03630.x

Hapfelmeier, Siegfried; Müller, Andreas J; Stecher, Bärbel; Kaiser, Patrick; Barthel, Manja; Endt, Kathrin; Eberhard, Matthias; Robbiani, Riccardo; Jacobi, Christoph A; Heikenwalder, Mathias; Kirschning, Carsten; Jung, Steffen; Stallmach, Thomas; Kremer, Marcus; Hardt, Wolf-Dietrich (2008). Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis. The Journal of experimental medicine, 205(2), pp. 437-450. Rockefeller Univ. Press 10.1084/jem.20070633

2007

Macpherson, Andrew J; Hapfelmeier, Siegfried; McCoy, Kathy D (2007). The armed truce between the intestinal microflora and host mucosal immunity. Seminars in immunology, 19(2), pp. 57-58. W.B. Saunders 10.1016/j.smim.2007.04.001

2006

Suar, Mrutyunjay; Jantsch, Jonathan; Hapfelmeier, Siegfried; Kremer, Marcus; Stallmach, Thomas; Barrow, Paul A; Hardt, Wolf-Dietrich (2006). Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Infection and immunity, 74(1), pp. 632-644. American Society for Microbiology 10.1128/IAI.74.1.632-644.2006

2005

Bifrare, Yoeng-Delphine; Kummer, Jürg; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2005). Brain-derived neurotrophic factor protects against multiple forms of brain injury in bacterial meningitis. Journal of infectious diseases, 191(1), pp. 40-45. Oxford University Press 10.1086/426399

Rhême, Céline; Ehrengruber, Markus U; Grandgirard, Denis (2005). Alphaviral cytotoxicity and its implication in vector development. Experimental physiology, 90(1), pp. 45-52. Blackwell 10.1113/expphysiol.2004.028142

Hapfelmeier, Siegfried; Hardt, Wolf-Dietrich (2005). A mouse model for S. typhimurium-induced enterocolitis. Trends in microbiology, 13(10), pp. 497-503. Elsevier Current Trends 10.1016/j.tim.2005.08.008

Stecher, Bärbel; Macpherson, Andrew J; Hapfelmeier, Siegfried; Kremer, Marcus; Stallmach, Thomas; Hardt, Wolf-Dietrich (2005). Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin. Infection and immunity, 73(6), pp. 3228-3241. American Society for Microbiology 10.1128/IAI.73.6.3228-3241.2005

Hapfelmeier, Siegfried; Stecher, Bärbel; Barthel, Manja; Kremer, Marcus; Müller, Andreas J; Heikenwalder, Mathias; Stallmach, Thomas; Hensel, Michael; Pfeffer, Klaus; Akira, Shizuo; Hardt, Wolf-Dietrich (2005). The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. Journal of immunology, 174(3), pp. 1675-1685. American Association of Immunologists

2004

Gianinazzi, Christian; Grandgirard, Denis; Simon, Franziska; Imboden, Hans; Joss, Philipp; Täuber, Martin G.; Leib, Stephen (2004). Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited. Journal of neuropathology and experimental neurology, 63(6), pp. 610-617. Lippincott Williams & Wilkins

Stecher, Bärbel; Hapfelmeier, Siegfried; Müller, Catherine; Kremer, Marcus; Stallmach, Thomas; Hardt, Wolf-Dietrich (2004). Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and immunity, 72(7), pp. 4138-4150. American Society for Microbiology 10.1128/IAI.72.7.4138-4150.2004

Ehrbar, Kristin; Hapfelmeier, Siegfried; Stecher, Bärbel; Hardt, Wolf-Dietrich (2004). InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium. Journal of bacteriology, 186(4), pp. 1215-1219. American Society for Microbiology 10.1128/JB.186.4.1215-1219.2004

Hapfelmeier, Siegfried; Ehrbar, Kristin; Stecher, Bärbel; Barthel, Manja; Kremer, Marcus; Hardt, Wolf-Dietrich (2004). Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice. Infection and immunity, 72(2), pp. 795-809. American Society for Microbiology 10.1128/IAI.72.2.795-809.2004

2003

Gianinazzi, Christian; Grandgirard, Denis; Imboden, Hans; Egger, Lotti; Meli, Damian N; Bifrare, Yoeng-Delphine; Joss, Philipp; Täuber, Martin G.; Borner, Christoph; Leib, Stephen (2003). Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica, 105(5), pp. 499-507. Springer 10.1007/s00401-003-0672-7

Barthel, Manja; Hapfelmeier, Siegfried; Quintanilla-Martínez, Leticia; Kremer, Marcus; Rohde, Manfred; Hogardt, Michael; Pfeffer, Klaus; Rüssmann, Holger; Hardt, Wolf-Dietrich (2003). Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infection and immunity, 71(5), pp. 2839-2858. American Society for Microbiology 10.1128/IAI.71.5.2839-2858.2003

2001

Baron, C; Domke, N; Beinhofer, M; Hapfelmeier, Siegfried (2001). Elevated temperature differentially affects virulence, VirB protein accumulation, and T-pilus formation in different Agrobacterium tumefaciens and Agrobacterium vitis strains. Journal of bacteriology, 183(23), pp. 6852-6861. American Society for Microbiology 10.1128/JB.183.23.6852-6861.2001

2000

Hapfelmeier, Siegfried; Domke, N; Zambryski, P C; Baron, C (2000). VirB6 is required for stabilization of VirB5 and VirB3 and formation of VirB7 homodimers in Agrobacterium tumefaciens. Journal of bacteriology, 182(16), pp. 4505-4511. American Society for Microbiology 10.1128/JB.182.16.4505-4511.2000

1998

Grandgirard, Denis; Studer, Erwin; Monney, Laurent; Belser, Tanja; Fellay, Isabelle; Borner, Christoph; Michel, Marcel R. (1998). Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2. EMBO journal, 17(5), pp. 1268-1278. Nature Publishing Group 10.1093/emboj/17.5.1268

1994

Leib, Stephen (1994). [A case from practice (305). Recurrent erysipelas--tinea pedis et unginum--chronic venous insufficiency]. Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis, 83(39), pp. 1089-1090.

1988

Schittny, Johannes C.; Timpl, Rupert; Engel, Jürgen (1988). High resolution immunoelectron microscopic localization of functional domains of laminin, nidogen, and heparan sulfate proteoglycan in epithelial basement membrane of mouse cornea reveals different topological orientations. Journal of cell biology, 107(4), pp. 1599-1610. Rockefeller Institute Press

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