Changes in viral hepatitis B screening practices over time in West African HIV clinics.

Coffie, P A; Patassi, A; Doumbia, A; Bado, G; Messou, E; Minga, A; Allah-Kouadio, E; Zannou, D M; Seydi, M; Kakou, A R; Dabis, F; Wandeler, Gilles (2017). Changes in viral hepatitis B screening practices over time in West African HIV clinics. Médecine et maladies infectieuses, 47(6), pp. 394-400. Elsevier Masson 10.1016/j.medmal.2017.04.011

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BACKGROUND We aimed to describe changes in hepatitis B screening practices over a 3-year period among HIV-infected patients in West Africa. METHODS A medical chart review was conducted in urban HIV treatment centers in Ivory Coast (3 sites), Benin, Burkina Faso, Senegal, and Togo (1 site each). Among patients who started antiretroviral treatment between 2010 and 2012, 100 per year were randomly selected from each clinic. Demographic, clinical, and laboratory data was collected using a standardized questionnaire. We assessed changes in the proportion of patients screened over time and identified predictors of screening in a multivariable logistic regression. RESULTS A total of 2097 patients were included (median age: 37 years, 65.4% of women). Overall, 313 (14.9%) patients had been screened for hepatitis B, with an increase from 10.6% in 2010 to 18.9% in 2012 (P<0.001) and substantial differences across countries. In multivariable analysis, being aged over 45 years (adjusted odds ratio: 1.34 [1.01-1.77]) and having an income-generating activity (adjusted odds ratio: 1.82 [1.09-3.03]) were associated with screening for hepatitis B infection. Overall, 62 HIV-infected patients (19.8%, 95% confidence interval: 15.5-24.7) were HBsAg-positive and 82.3% of them received a tenofovir-containing drug regimen. CONCLUSION Hepatitis B screening among HIV-infected patients was low between 2010 and 2012. The increasing availability of HBsAg rapid tests and tenofovir in first-line antiretroviral regimen should improve the rates of hepatitis B screening.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Wandeler, Gilles

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0399-077X

Publisher:

Elsevier Masson

Language:

English

Submitter:

Annelies Luginbühl

Date Deposited:

04 Jul 2017 11:58

Last Modified:

23 May 2018 02:30

Publisher DOI:

10.1016/j.medmal.2017.04.011

PubMed ID:

28545675

Uncontrolled Keywords:

Afrique subsaharienne Dépistage HBV HIV-infected patients Patients infectés par le VIH Screening Sub-Saharan Africa VHB

BORIS DOI:

10.7892/boris.101014

URI:

https://boris.unibe.ch/id/eprint/101014

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