New role of ventricular assist devices as bridge to transplantation: European perspective.

Reineke, David Christian; Mohacsi, Paul (2017). New role of ventricular assist devices as bridge to transplantation: European perspective. Current opinion in organ transplantation, 22(3), pp. 225-230. Lippincott Williams & Wilkins 10.1097/MOT.0000000000000412

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PURPOSE OF REVIEW Progress of ventricular assist devices (VAD) technology led to improved survival and apparently low morbidity. However, from the European perspective, updated analysis of EUROMACS reveals a somewhat less impressive picture with respect to mortality and morbidity. RECENT FINDINGS We describe the great demand of cardiac allografts versus the lack of donors, which is larger in Europe than in the United States. Technical progress of VADs made it possible to work out a modern algorithm of bridge-to-transplant, which is tailored to the need of the particular patient. We analyze the burden of patients undergoing bridge-to-transplant therapy. They are condemned to an intermediate step, coupled with additional major surgery and potential adverse events during heart transplantation. SUMMARY Based on current registry data, we do have to question the increasingly popular opinion, that the concept of heart transplantation is futureless, which seems to be for someone who treats and compares both patients (VAD and heart transplantation) in daily practice, questionable. Up to now, left ventricular assist device therapy remains a bridge to a better future, which means a bridge to technical innovations or to overcome the dramatic lack of donors in Europe.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Reineke, David Christian and Mohacsi, Paul

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1087-2418

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Daniela Huber

Date Deposited:

21 Sep 2017 17:31

Last Modified:

21 Sep 2017 17:31

Publisher DOI:

10.1097/MOT.0000000000000412

PubMed ID:

28362668

BORIS DOI:

10.7892/boris.101647

URI:

https://boris.unibe.ch/id/eprint/101647

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