REM sleep and memory.

Boyce, Richard; Williams, Sylvain; Adamantidis, Antoine Roger (2017). REM sleep and memory. Current opinion in neurobiology, 44, pp. 167-177. Elsevier 10.1016/j.conb.2017.05.001

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Memory consolidation, a process which stabilizes recently acquired information into long-term storage, is thought to be optimized during sleep. Although recent evidence indicates that non-rapid-eye movement sleep (NREMs) is directly involved in memory consolidation, the role of rapid-eye movement sleep (REMs) in this process has remained controversial due to the extreme difficulty in experimentally isolating neural activity during REMs. Using a combination of electrophysiological recording and optogenetic techniques, recent work demonstrated for the first time that neural activity occurring specifically during REMs is required for spatial and contextual memory consolidation. Identifying the underlying mechanisms behind these observations, precisely how they translate to humans, and clarifying the extent of REMs' role in other modalities of memory are important challenges of future research with implications for human health.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Adamantidis, Antoine Roger

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0959-4388

Publisher:

Elsevier

Language:

English

Submitter:

Stefanie Hetzenecker

Date Deposited:

16 Oct 2017 17:31

Last Modified:

16 Oct 2017 17:31

Publisher DOI:

10.1016/j.conb.2017.05.001

PubMed ID:

28544929

BORIS DOI:

10.7892/boris.102099

URI:

https://boris.unibe.ch/id/eprint/102099

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