Gesture impairments in schizophrenia are linked to increased movement and prolonged motor planning and execution.

Dutschke, Lars Levi; Stegmayer, Katharina; Ramseyer, Fabian; Bohlhalter, Stephan; Vanbellingen, Tim; Strik, Werner; Walther, Sebastian (2018). Gesture impairments in schizophrenia are linked to increased movement and prolonged motor planning and execution. Schizophrenia Research, 200, pp. 42-49. Elsevier 10.1016/j.schres.2017.07.012

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Schizophrenia patients present with a variety of impaired nonverbal communication skills. Performance of hand gestures is frequently impaired and associated with ratings of motor abnormalities. However, the impact of motor abnormalities to gesture performance remains unclear. To test the association between quantitative measures of motor behavior and qualitative ratings of gesture performance, we quantified movement parameters semi-automatically in videotaped recordings of gesture assessment. Thirty-one patients with schizophrenia (77.4%), schizophreniform (19.4%) or schizoaffective disorder (3.2%) and 32 healthy controls matched for age, gender and education underwent clinical assessment. Performance of the test of upper limb apraxia (TULIA) was video-taped in all subjects. The videos were analyzed with motion energy analysis software (MEA) to determine motion and time parameters. Patients and controls differed significantly in quantitative gesture performance: patients required more movement and more time to complete the tasks. Differences increased in patients with qualitatively impaired gesture production ratings (p<0.01). Group differences were most pronounced in the pantomime domain, when gestures are performed following verbal instruction. In patients, ratings of motor abnormalities correlated with duration of movement, while behavioral disorganization correlated with the amount of movements during gesture performance. Disorder related motor symptoms, aberrant action observation, planning and monitoring as well as internal clock abnormalities may explain the poor performance of hand gestures in schizophrenia. Quantitative video analysis offers a unique possibility to analyze movement patterns as a direct functional output of the motor system. In the future, it may assist monitoring, staging and prognosis in schizophrenia.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center
07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy
07 Faculty of Human Sciences > Institute of Psychology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Dutschke, Lars Levi; Stegmayer, Katharina; Ramseyer, Fabian; Bohlhalter, Stephan; Vanbellingen, Tim; Strik, Werner and Walther, Sebastian

Subjects:

100 Philosophy > 150 Psychology
600 Technology > 610 Medicine & health

ISSN:

0920-9964

Publisher:

Elsevier

Language:

English

Submitter:

Stefanie Hetzenecker

Date Deposited:

24 Oct 2017 10:44

Last Modified:

27 Sep 2018 01:30

Publisher DOI:

10.1016/j.schres.2017.07.012

PubMed ID:

28709771

Uncontrolled Keywords:

Action monitoring Gesture performance Motion energy analysis Motor system Tulia Video analysis

BORIS DOI:

10.7892/boris.102450

URI:

https://boris.unibe.ch/id/eprint/102450

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