Walter, Martin A; Hildebrandt, Isabel J; Hacke, Katrin; Kesner, Adam L; Kelly, Owen; Lawson, Gregory W; Phelps, Michael E; Czernin, Johannes; Weber, Wolfgang A; Schiestl, Robert H (2010). Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. Journal of nuclear medicine, 51(8), pp. 1285-92. New York, N.Y.: Society of Nuclear Medicine 10.2967/jnumed.109.073585
Full text not available from this repository. (Request a copy)Transgenic mouse models of human cancers represent one of the most promising approaches to elucidate clinically relevant mechanisms of action and provide insights into the treatment efficacy of new antitumor drugs. The use of Trp53 transgenic mice (Trp53 knockout [Trp53(-/-)] mice) for these kinds of studies is, so far, restricted by limitations in detecting developing tumors and the lack of noninvasive tools for monitoring tumor growth, progression, and treatment response.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Clinic of Nuclear Medicine |
UniBE Contributor: |
Walter, Martin Alexander |
ISSN: |
0161-5505 |
Publisher: |
Society of Nuclear Medicine |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:09 |
Last Modified: |
05 Dec 2022 14:00 |
Publisher DOI: |
10.2967/jnumed.109.073585 |
PubMed ID: |
20660381 |
Web of Science ID: |
000280645600027 |
URI: |
https://boris.unibe.ch/id/eprint/1029 (FactScience: 201709) |
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