Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study.

Pajic, Bojan; Aebersold, Daniel; Eggspuehler, Andreas; Theler, Frederik R; Studer, Harald P (2017). Biomechanical Modeling of Pterygium Radiation Surgery: A Retrospective Case Study. Sensors, 17(6) Molecular Diversity Preservation International MDPI 10.3390/s17061200

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Pterygium is a vascularized, invasive transformation on the anterior corneal surface that can be treated by Strontium-/Yttrium90 beta irradiation. Finite element modeling was used to analyze the biomechanical effects governing the treatment, and to help understand clinically observed changes in corneal astigmatism. Results suggested that irradiation-induced pulling forces on the anterior corneal surface can cause astigmatism, as well as central corneal flattening. Finite element modeling of corneal biomechanics closely predicted the postoperative corneal surface (astigmatism error -0.01D; central curvature error -0.16D), and can help in understanding beta irradiation treatment. Numerical simulations have the potential to preoperatively predict corneal shape and function changes, and help to improve corneal treatments.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Pajic, Bojan and Aebersold, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1424-8220

Publisher:

Molecular Diversity Preservation International MDPI

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

23 Feb 2018 13:53

Last Modified:

23 Feb 2018 14:01

Publisher DOI:

10.3390/s17061200

PubMed ID:

28538668

Uncontrolled Keywords:

biomechanics cornea surgery finite element modeling pterygium radiation simulation

BORIS DOI:

10.7892/boris.105267

URI:

https://boris.unibe.ch/id/eprint/105267

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