Aorta Related and All-cause Mortality in Patients with Aortic Intramural Haematoma.

Schönhoff, Florian; Zanchin, Christian; Czerny, M; Makaloski, Vladimir; Gahl, Brigitta; Carrel, Thierry; Schmidli, Jürg (2017). Aorta Related and All-cause Mortality in Patients with Aortic Intramural Haematoma. European journal of vascular and endovascular surgery EJVES, 54(4), pp. 447-453. Elsevier 10.1016/j.ejvs.2017.07.001

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OBJECTIVES The prognosis of patients with intramural haematoma (IMH) of the aorta beyond the first year after diagnosis remains largely unknown. In particular, patients that do not undergo interventions are lost to follow-up. The aim was to assess medium-term outcome in IMH patients. METHODS Post hoc analysis of 63 consecutive patients presenting with IMH between 1999 and 2013 was performed. Patients meeting imaging criteria at the first presentation were included even if follow-up imaging showed evidence of intimal disruption or false lumen flow. RESULTS Eighteen patients presented with type A and 45 with type B IMH (29% vs. 71%, p < .001). The mean age was 71 ± 9.2 years, range 42-88 years. Follow-up was completed in 97% of patients by May 2017 and represents a mean follow-up of 6.3 ± 3.6 years. Freedom from intervention in patients with type B IMH was 40%. TEVAR was performed in 47% because of development, unmasking of an entry tear (57%), progression to acute type B dissection (24%), or subsequent dilation of the affected aortic segments (19%). Open repair was performed in 13% of type B IMH patients because of dilation of the descending aorta. In type A IMH, 89% underwent open repair. Aorta related 30 day, 6 month, 1 year, and late mortality were 1.6%, 6.3%, 6.3%, and 9.5%, respectively, for all IMH patients. All-cause 30 day, 6 month, 1 year, and late mortality were 1.6%, 6.3%, 6.3%, and 47.6%, respectively, for all IMH patients. Late mortality in type B IMH did not differ whether patients underwent TEVAR, open repair, or received best medical treatment only (26% vs. 22%, p = 1.0). CONCLUSIONS Late aorta related mortality in IMH was low whereas all-cause mortality was substantial. Aorta related mortality in IMH patients only occurs during the first year after diagnosis. Interventions after the first year are rarely necessary.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Schönhoff, Florian; Zanchin, Christian; Makaloski, Vladimir; Gahl, Brigitta; Carrel, Thierry and Schmidli, Jürg

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1078-5884

Publisher:

Elsevier

Language:

English

Submitter:

Daniela Huber

Date Deposited:

20 Sep 2017 08:51

Last Modified:

26 Sep 2017 01:32

Publisher DOI:

10.1016/j.ejvs.2017.07.001

PubMed ID:

28802635

Uncontrolled Keywords:

Aortic dissection Aortic surgery Intramural haematoma TEVAR

BORIS DOI:

10.7892/boris.105416

URI:

https://boris.unibe.ch/id/eprint/105416

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