No effects of transcranial DLPFC stimulation on implicit task sequence learning and consolidation

Savic, Branislav; Cazzoli, Dario; Müri, René; Meier, Beat (2017). No effects of transcranial DLPFC stimulation on implicit task sequence learning and consolidation. Scientific Reports, 7(9649), pp. 1-10. Nature Publishing Group 10.1038/s41598-017-10128-0

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Neurostimulation of the dorsolateral prefrontal cortex (DLPFC) can modulate performance in cognitive tasks. In a recent study, however, transcranial direct current stimulation (tDCS) of the DLPFC did not affect implicit task sequence learning and consolidation in a paradigm that involved bimanual responses. Because bimanual performance increases the coupling between homologous cortical areas of the hemispheres and left and right DLPFC were stimulated separately the null findings may have been due to the bimanual setup. The aim of the present study was to test the effect of neuro-stimulation on sequence learning in a uni-manual setup. For this purpose two experiments were conducted. In Experiment 1, the DLPFC was stimulated with tDCS. In Experiment 2 the DLPFC was stimulated with transcranial magnetic stimulation (TMS). In both experiments, consolidation was measured 24 hours later. The results showed that sequence learning was present in all conditions and sessions, but it was not influenced by stimulation. Likewise, consolidation of sequence learning was robust across sessions, but it was not influenced by stimulation. These results replicate and extend previous findings. They indicate that established tDCS and TMS protocols on the DLPFC do not influence implicit task sequence learning and consolidation.

Item Type:

Journal Article (Original Article)

Division/Institute:

07 Faculty of Human Sciences > Institute of Psychology > Experimental Psychology and Neuropsychology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Savic, Branislav; Cazzoli, Dario; Müri, René Martin and Meier, Beat

Subjects:

100 Philosophy > 150 Psychology

ISSN:

2045-2322

Publisher:

Nature Publishing Group

Language:

English

Submitter:

Branislav Savic

Date Deposited:

09 Nov 2017 13:08

Last Modified:

09 Nov 2017 13:15

Publisher DOI:

10.1038/s41598-017-10128-0

PubMed ID:

28852114

BORIS DOI:

10.7892/boris.105439

URI:

https://boris.unibe.ch/id/eprint/105439

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