Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells

Keller, M; Lerch, M; Britschgi, M; Tâche, V; Gerber, B O; Lüthi, M; Lochmatter, P; Kanny, G; Bircher, A J; Christiansen, C; Pichler, W J (2010). Processing-dependent and -independent pathways for recognition of iodinated contrast media by specific human T cells. Clinical and experimental allergy, 40(2), pp. 257-68. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2222.2009.03425.x

Full text not available from this repository. (Request a copy)

One to three percent of patients exposed to intravenously injected iodinated contrast media (CM) develop delayed hypersensitivity reactions. Positive patch test reactions, immunohistological findings, and CM-specific proliferation of T cells in vitro suggest a pathogenetic role for T cells. We have previously demonstrated that CM-specific T cell clones (TCCs) show a broad range of cross-reactivity to different CM. However, the mechanism of specific CM recognition by T cell receptors (TCRs) has not been analysed so far.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Groux, Monika; Gerber, Basil Oliver; Lüthi, Michael; Lochmatter, Priska and Pichler, Werner Joseph

ISSN:

0954-7894

Publisher:

Blackwell Scientific Publications

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1111/j.1365-2222.2009.03425.x

PubMed ID:

20030663

Web of Science ID:

000273547500011

URI:

https://boris.unibe.ch/id/eprint/106 (FactScience: 195935)

Actions (login required)

Edit item Edit item
Provide Feedback