Low incidence of subsequent bacteremia or fungemia after removal of a colonized intravascular catheter tip.

Buetti, Niccolò Ivo Marco-Aurelio; Lo Priore, Elia Francesco; Atkinson, Andrew; Kronenberg, Andreas Oskar; Marschall, Jonas (2018). Low incidence of subsequent bacteremia or fungemia after removal of a colonized intravascular catheter tip. Clinical microbiology and infection, 24(5), 548.e1-548.e3. Elsevier 10.1016/j.cmi.2017.09.009

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OBJECTIVES We determined the frequency of subsequent bloodstream infection >2 days after removal of a catheter with positive tip cultures. METHODS We conducted a nationwide, observational study on intravascular catheter (IVC) tip cultures in Switzerland from 2008 to 2015 using data from the Swiss Antibiotic Resistance Surveillance System (ANRESIS). An IVC tip culture was included in the analysis if ≥1 microorganism could be cultivated from it. We excluded all data from patients with concurrent bacteremia with the same microorganism identified 7 days before to 2 days after IVC removal. Subsequent bloodstream infection (sBSI) was defined as isolating (from blood cultures performed >2 days up to 7 days after catheter removal) the same microorganism as the one recovered from the IVC. Data on antibiotic therapy were not available in this surveillance study. RESULTS Over the 8-year period, 15'033 positive IVC tip cultures were identified. Our study population comprised 12'513 episodes of positive IVC tip cultures without concurrent bacteremia. The frequency of sBSI was 1.8% (n=219). Subsequent bloodstream infections were more frequently detected after the identification of C. albicans (10/113, 8.8%), S. marcescens (9/169, 5.3%) and S. aureus (30/623, 4.8%) on a catheter tip. CONCLUSIONS A very low incidence of subsequent BSI was observed if a microorganism was identified on a removed IVC tip without concurrent bacteremia. The risk of subsequent BSI increased if C. albicans, S. aureus or S. marcescens were identified in this context.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

UniBE Contributor:

Buetti, Niccolò Ivo Marco-Aurelio; Lo Priore, Elia Francesco; Atkinson, Andrew; Kronenberg, Andreas Oskar and Marschall, Jonas

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1198-743X

Publisher:

Elsevier

Language:

English

Submitter:

Annelies Luginbühl

Date Deposited:

06 Dec 2017 10:13

Last Modified:

10 Apr 2019 14:39

Publisher DOI:

10.1016/j.cmi.2017.09.009

PubMed ID:

28962996

Uncontrolled Keywords:

catheter tip subsequent bloodstream infection

BORIS DOI:

10.7892/boris.106097

URI:

https://boris.unibe.ch/id/eprint/106097

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