Introducing supramolecular polymers to DNA nanotechnology

Vyborna, Yuliia; Häner, Robert (6 November 2017). Introducing supramolecular polymers to DNA nanotechnology (Unpublished). In: Swiss Conference on Supramolecular Polymers 2017.

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Self‐assembly of DNA‐containing molecules into biocompatible functional materials has attracted
considerable attention over the last years. In this contribution, we present our recent findings in the field
of self‐assembled DNA conjugates and their potential applications as stimuli‐responsive materials, cargo
binding vehicles, and energy transfer platforms. The DNA conjugates consist of a short oligonucleotide
strand covalently bound to an array of phosphodiester‐linked pyrenes. Depending on the strand
composition and conditions, the self‐assembly governed by the stacking and hydrophobic interactions
between pyrenes leads to a variety of shapes: micelles, one‐dimensional ribbons and two‐dimensional
nanosheets. In the case of 1D structures (DNA‐grafted supramolecular polymers), the polymer core is
formed by the stacked pyrenes, whereas the oligonucleotides are arranged at the edges of the ribbons in
a comb‐like fashion. The abstract plus figure must not exceed one page. Page margins must not be
changed.

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Vyborna, Yuliia and Häner, Robert

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

Language:

English

Submitter:

Yuliia Vyborna

Date Deposited:

23 Nov 2017 08:47

Last Modified:

28 Nov 2019 20:08

BORIS DOI:

10.7892/boris.106825

URI:

https://boris.unibe.ch/id/eprint/106825

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