Variation in recombination frequency and distribution across eukaryotes: patterns and processes

Stapley, Jessica; Feulner, Philine; Johnston, Susan E.; Santure, Anna W.; Smadja, Carole M. (2017). Variation in recombination frequency and distribution across eukaryotes: patterns and processes. Philosophical transactions of the Royal Society. Series B - biological sciences, 372(1736) Royal Society of London 10.1098/rstb.2016.0455

[img]
Preview
Text
Stapley Feulner et al. 2017 PhilTransB Variation in recombination frequency and distribution across eukaryotes.pdf - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (1MB) | Preview

Recombination, the exchange of DNA between maternal and paternal chromosomes during meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms. While the role of recombination in the evolution of sex has received theoretical and empirical attention, less is known about how recombination rate itself evolves and what influence this has on evolutionary processes within sexually reproducing organisms. Here, we explore the patterns of, and processes governing recombination in eukaryotes. We summarize patterns of variation, integrating current knowledge with an analysis of linkage map data in 353 organisms. We then discuss proximate and ultimate processes governing recombination rate variation and consider how these influence evolutionary processes. Genome-wide recombination rates (cM/Mb) can vary more than tenfold across eukaryotes, and there is large variation in the distribution of recombination events across closely related taxa, populations and individuals. We discuss how variation in rate and distribution relates to genome architecture, genetic and epigenetic mechanisms, sex, environmental perturbations and variable selective pressures. There has been great progress in determining the molecular mechanisms governing recombination, and with the continued development of new modelling and empirical approaches, there is now also great opportunity to further our understanding of how and why recombination rate varies. This article is part of the themed issue ‘Evolutionary causes and consequences of recombination rate variation in sexual organisms’.

Item Type:

Journal Article (Review Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Aquatic Ecology

UniBE Contributor:

Feulner, Philine

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0962-8436

Publisher:

Royal Society of London

Language:

English

Submitter:

Marcel Häsler

Date Deposited:

12 Dec 2017 17:22

Last Modified:

25 Oct 2019 11:25

Publisher DOI:

10.1098/rstb.2016.0455

PubMed ID:

29109219

BORIS DOI:

10.7892/boris.107137

URI:

https://boris.unibe.ch/id/eprint/107137

Actions (login required)

Edit item Edit item
Provide Feedback