New Macrolide-Lincosamide-Streptogramin B Resistance Gene erm(48) on the Novel Plasmid pJW2311 in Staphylococcus xylosus.

Wipf, Juliette Ramona Karin; Riley, Matthew C; Kania, Stephen A; Bemis, David A; Andreis, Sabrina Nathalie; Schwendener, Sybille; Perreten, Vincent (2017). New Macrolide-Lincosamide-Streptogramin B Resistance Gene erm(48) on the Novel Plasmid pJW2311 in Staphylococcus xylosus. Antimicrobial agents and chemotherapy, 61(7) American Society for Microbiology 10.1128/AAC.00066-17

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Whole-genome sequencing of Staphylococcus xylosus strain JW2311 from bovine mastitis milk identified the novel 49.3-kb macrolide-lincosamide-streptogramin B (MLSB) resistance plasmid pJW2311. It contained the macrolide resistance gene mph(C), the macrolide-streptogramin B resistance gene msr(A), and the new MLSB resistance gene erm(48) and could be transformed into Staphylococcus aureus by electroporation. Functionality of erm(48) was demonstrated by cloning and expression in S. aureus.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology > Molecular Bacterial Epidemiology and Infectiology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Wipf, Juliette Ramona Karin; Andreis, Sabrina Nathalie; Schwendener, Sybille and Perreten, Vincent

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 630 Agriculture

ISSN:

0066-4804

Publisher:

American Society for Microbiology

Language:

English

Submitter:

Vincent Perreten

Date Deposited:

10 Apr 2018 09:11

Last Modified:

10 Apr 2018 09:17

Publisher DOI:

10.1128/AAC.00066-17

PubMed ID:

28438941

Uncontrolled Keywords:

Staphylococcus animal antibiotic resistance bovine milk macrolide macrolide-lincosamide-streptogramin B plasmid-mediated resistance rRNA methylase

BORIS DOI:

10.7892/boris.107228

URI:

https://boris.unibe.ch/id/eprint/107228

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