Grewal, Dilraj S; Merlau, Daniel J; Giri, Pushpanjali; Munk, Marion; Fawzi, Amani A; Jampol, Lee M; Tanna, Angelo P (2017). Peripapillary retinal splitting visualized on OCT in glaucoma and glaucoma suspect patients. PLoS ONE, 12(8), e0182816. Public Library of Science 10.1371/journal.pone.0182816
|
Text
pone.0182816(1).pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (9MB) | Preview |
PURPOSE
To identify the risk factors for development of peripapillary retinal splitting (schisis) in patients with glaucoma or suspicion of glaucoma.
SETTING
Glaucoma Clinic, Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL.
METHODS
In this institutional cross-sectional study, 495 patients (990 eyes) who had undergone spectral-domain optical coherence tomography (OCT Spectralis HRA-OCT, Heidelberg Engineering) optic nerve head (ONH) imaging and did not have identifiable optic nerve pits, pseudopits or coloboma were included. OCT scans were reviewed by two observers.
MAIN OUTCOME MEASURES
Presence of peripapillary retinal splitting identified on OCT raster scans.
RESULTS
Eleven of 990 glaucoma and glaucoma suspect eyes (1.1%) of 7 patients (2 females, 5 males, mean age 64.5 ± 9.2 years) had peripapillary retinal splitting. Two of these 11 eyes had extension of the splitting into the macula but none to the fovea. Of these 11 patients, 2 (28.6%) were glaucoma suspects, 3 (42.9%) had primary open-angle glaucoma, 1 (14.3%) had chronic angle-closure glaucoma and 1 (14.3%) had pigmentary glaucoma. 7/11 (63.6%) eyes had vitreous traction to the disc visualized on OCT and 6/11 eyes (54.5%) had beta-zone peripapillary atrophy.
CONCLUSIONS
We observed peripapillary retinal splitting in 1.1% of a series of 990 glaucoma and glaucoma-suspect eyes. Evidence of adherent vitreous with traction and peripapillary atrophy was found in a majority of the involved eyes. A comparison to an age and axial length matched cohort is required to determine if this is a condition that is associated with glaucoma.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Munk, Marion |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Marion Munk |
Date Deposited: |
14 Dec 2017 08:09 |
Last Modified: |
05 Dec 2022 15:08 |
Publisher DOI: |
10.1371/journal.pone.0182816 |
PubMed ID: |
28832670 |
BORIS DOI: |
10.7892/boris.107274 |
URI: |
https://boris.unibe.ch/id/eprint/107274 |
Actions (login required)
 |
Edit item |