General anaesthesia for patients with a history of a contrast medium-induced anaphylaxis: a useful prophylaxis?

Böhm, Ingrid; Nairz, Knud; Morelli, John; Silva Hasembank de Licini, Patricia; Heverhagen, Johannes (2017). General anaesthesia for patients with a history of a contrast medium-induced anaphylaxis: a useful prophylaxis? British journal of radiology, 90(1079), p. 20160647. British Institute of Radiology 10.1259/bjr.20160647

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Contrast-enhanced radiological examinations are important diagnostic tools in modern medicine. Currently, all approved and available iodinated and gadolinium-based contrast agents are safe and well-tolerated by most patients. However, approximately 2% of patients receiving iodinated contrast media exhibit hypersensitivity reactions. Patients with a history of such a reaction are at increased risk upon reexposure. Therefore, they are subjected to a prophylaxis such as injection of antiallergy drugs or general anaesthesia. The latter procedure is expensive, can burden the patients organism, and besides lacks objective verification. Therefore, the purpose of our review paper is to present and discuss the background and the previous practice, as well as to provide a proposal for a safe individual patient management.

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