Micro-filled resin infiltration of fissure caries lesions in vitro.

Lausch, J; Askar, H; Paris, S; Meyer-Lückel, Hendrik (2017). Micro-filled resin infiltration of fissure caries lesions in vitro. Journal of dentistry, 57, pp. 73-76. Elsevier Science 10.1016/j.jdent.2016.12.010

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OBJECTIVES The aim of this in vitro study was to evaluate three treatment modalities [infiltrant resin (IR), micro-filled infiltrant resin (MFIR), infiltrant-sealant-combination (ISC)] regarding both their abilities to penetrate lesions differing in ICDAS-codes and to fill fissures and cavities. MATERIALS AND METHODS Extracted human molars (n=90) showing fissure caries lesions with and without cavitations were etched with 15% hydrochloric acid (HCl) that was mixed with abrasives and a 15% HCl-solution (1:1). The etching gel was rubbed for 30s within the fissure and, if eligible, within the cavity using a brush. After this pretreatment an infiltrant (Icon; DMG; IR) or an infiltrant mixed with microfillers (MFIR) was applied. ISC included the application of an infiltrant followed by a fissure sealant (Helioseal; Ivoclar Vivadent) From each tooth slices showing a non-cavitated (based on ICDAS-2) or cavitated lesion part (based on ICDAS-3/5) were prepared. Lesion (LA) and penetration areas (PA) as well as the completeness of fissure and cavity filling were analyzed using dual staining and confocal laser scanning microscopy. RESULTS Percentage penetration (PP) was calculated as 100×PA/LA. PP [median (25th/75th)] did not differ significantly between IR [95 (86/100)%], MFIR [93 (62/100)%] or ISC [89 (67/97)%] (p>0.05; Kruskal-Wallis test). All three materials filled about 90% of the dimensions of fissures and cavities (p>0.05; Kruskal-Wallis test). CONCLUSION It can be concluded that MFIR seems to be suitable to fill fissures and cavities like a fissure sealant and that it penetrates fissure caries lesions similarly deep as the conventional infiltrant after an experimental etching regime. CLINICAL SIGNIFICANCE The MFIR seems to combine advantages of the fissure sealing and the caries infiltration procedure.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry

UniBE Contributor:

Meyer-Lückel, Hendrik


600 Technology > 610 Medicine & health




Elsevier Science




Hendrik Meyer-Lückel

Date Deposited:

10 Jan 2018 16:03

Last Modified:

24 Oct 2019 15:22

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Caries infiltration ICDAS Infiltrant Microfiller Occlusal lesions Sealing





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