The impact of pseudophakia on vision-related quality of life in the general population - The Gutenberg Health Study.

Schuster, Alexander K; Pfeiffer, Norbert; Schulz, Andreas; Nickels, Stefan; Höhn, René; Wild, Philipp S; Blettner, Maria; Münzel, Thomas; Beutel, Manfred E; Lackner, Karl J; Vossmerbaeumer, Urs (2017). The impact of pseudophakia on vision-related quality of life in the general population - The Gutenberg Health Study. Aging, 9(3), pp. 1030-1040. Impact Journals 10.18632/aging.101208

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Cataract surgery is the most frequently performed surgical procedure worldwide. We aim to determine the prevalence of having implanted an artificial lens (pseudophakia) and of no lens (aphakia) and to compare visual function.As part of the Gutenberg Health study, a population-based cross-sectional study was conducted in Germany. An ophthalmological examination including slit-lamp examination was conducted. Prevalence including 95% confidential intervals were calculated and analyses were conducted for systemic and ocular associated factors with pseudophakia using multivariable logistic regression models. Vision-related quality of life was assessed using a standardized questionnaire and Rasch transformation.14,696 people were included. Of these, 1.55% [1.36%-1.77%] had unilateral pseudophakia and 3.08% [2.81%-3.37%] had bilateral pseudophakia. Unilateral aphakia was present in 21 people and bilateral aphakia in 2 people. Pseudophakia was independently associated with age, higher body weight and lower body height, diabetes and smoking. Vision-related quality of life values were similar for those with bilateral phakia and pseudophakia but were lower for those with unilateral pseudophakia.The pseudophakia status is related to several cardiovascular risk factors, indicating a relationship to an aging effect that causes premature lens opacification. Bilateral pseudophakia can almost imitate the physiological condition of phakia except for the need to use glasses.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Höhn, René Gerhard Joachim


600 Technology > 610 Medicine & health




Impact Journals




René Gerhard Joachim Höhn

Date Deposited:

27 Feb 2018 15:06

Last Modified:

16 Jan 2021 15:36

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

aphakia cataract surgery epidemiology pseudophakia quality of life




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